DE69903717T2 - Mangan (ii) chelate mit hoher in-serum relaxivität - Google Patents

Mangan (ii) chelate mit hoher in-serum relaxivität

Info

Publication number
DE69903717T2
DE69903717T2 DE69903717T DE69903717T DE69903717T2 DE 69903717 T2 DE69903717 T2 DE 69903717T2 DE 69903717 T DE69903717 T DE 69903717T DE 69903717 T DE69903717 T DE 69903717T DE 69903717 T2 DE69903717 T2 DE 69903717T2
Authority
DE
Germany
Prior art keywords
relaxivity
manganic
chelates
serum
serum relaxivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69903717T
Other languages
English (en)
Other versions
DE69903717D1 (de
Inventor
Marino Brocchetta
Luisella Calabi
Franco Fedeli
Giuseppe Manfredi
Lino Paleari
Fulvio Uggeri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco SpA
Bracco Imaging SpA
Original Assignee
Bracco SpA
Bracco Imaging SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco SpA, Bracco Imaging SpA filed Critical Bracco SpA
Publication of DE69903717D1 publication Critical patent/DE69903717D1/de
Application granted granted Critical
Publication of DE69903717T2 publication Critical patent/DE69903717T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69903717T 1998-03-10 1999-03-09 Mangan (ii) chelate mit hoher in-serum relaxivität Expired - Lifetime DE69903717T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI980477 IT1298614B1 (it) 1998-03-10 1998-03-10 Chelati complessi di manganese ad alta relassivita' in siero
PCT/EP1999/001500 WO1999045968A1 (en) 1998-03-10 1999-03-09 Manganese chelates with high relaxivity in serum

Publications (2)

Publication Number Publication Date
DE69903717D1 DE69903717D1 (de) 2002-12-05
DE69903717T2 true DE69903717T2 (de) 2003-03-20

Family

ID=11379243

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69903717T Expired - Lifetime DE69903717T2 (de) 1998-03-10 1999-03-09 Mangan (ii) chelate mit hoher in-serum relaxivität

Country Status (5)

Country Link
EP (1) EP1061957B1 (de)
JP (1) JP2002506050A (de)
DE (1) DE69903717T2 (de)
IT (1) IT1298614B1 (de)
WO (1) WO1999045968A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980148A (en) * 1985-02-06 1990-12-25 Mallinckrodt, Inc. Methods for enhancing magnetic resonance imaging
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
IT1290417B1 (it) * 1996-08-02 1998-12-03 Bracco Spa Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed
IT1283650B1 (it) * 1996-08-02 1998-04-23 Bracco Spa Chelati paramagnetici ad alta relassivita' in siero

Also Published As

Publication number Publication date
EP1061957B1 (de) 2002-10-30
DE69903717D1 (de) 2002-12-05
EP1061957A1 (de) 2000-12-27
IT1298614B1 (it) 2000-01-12
JP2002506050A (ja) 2002-02-26
ITMI980477A1 (it) 1999-09-10
WO1999045968A1 (en) 1999-09-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition