DE69839393D1 - Stimulierung, züchtung und erhalt pankreatischer und anderer zellen - Google Patents
Stimulierung, züchtung und erhalt pankreatischer und anderer zellenInfo
- Publication number
- DE69839393D1 DE69839393D1 DE69839393T DE69839393T DE69839393D1 DE 69839393 D1 DE69839393 D1 DE 69839393D1 DE 69839393 T DE69839393 T DE 69839393T DE 69839393 T DE69839393 T DE 69839393T DE 69839393 D1 DE69839393 D1 DE 69839393D1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- stimulation
- cellulose derivative
- pancreatic beta
- pancreatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000638 stimulation Effects 0.000 title abstract 3
- 229920002678 cellulose Polymers 0.000 abstract 6
- 239000001913 cellulose Substances 0.000 abstract 6
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 6
- 210000002237 B-cell of pancreatic islet Anatomy 0.000 abstract 3
- 102000004877 Insulin Human genes 0.000 abstract 3
- 108090001061 Insulin Proteins 0.000 abstract 3
- 229940125396 insulin Drugs 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9700983A SE9700983D0 (sv) | 1997-03-18 | 1997-03-18 | Stimulering, odling och preservation av pankreas- och andra celler |
| SE9700983 | 1997-03-18 | ||
| PCT/SE1998/000475 WO1998041617A1 (en) | 1997-03-18 | 1998-03-16 | Stimulation, culture and preservation of pancreatic and other cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69839393D1 true DE69839393D1 (de) | 2008-06-05 |
| DE69839393T2 DE69839393T2 (de) | 2009-06-04 |
Family
ID=20406207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69839393T Expired - Lifetime DE69839393T2 (de) | 1997-03-18 | 1998-03-16 | Stimulierung, züchtung und erhalt pankreatischer und anderer zellen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6479283B1 (de) |
| EP (1) | EP0975739B1 (de) |
| JP (1) | JP4237265B2 (de) |
| AT (1) | ATE393214T1 (de) |
| AU (1) | AU6431398A (de) |
| CA (1) | CA2283676C (de) |
| DE (1) | DE69839393T2 (de) |
| SE (1) | SE9700983D0 (de) |
| WO (1) | WO1998041617A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8033401A (en) * | 2000-06-28 | 2002-01-08 | Ascendia Ab | Dna/rna-embedding medium and method of use |
| US20040186180A1 (en) | 2003-03-21 | 2004-09-23 | Gelotte Cathy K. | Non-steroidal anti-inflammatory drug dosing regimen |
| US20110071107A1 (en) * | 2006-10-20 | 2011-03-24 | Stephanie K Lynch | Uses of water-soluble cellulose derivatives for preventing or treating metabolic syndrome |
| WO2008136733A1 (en) | 2007-05-04 | 2008-11-13 | Ascendia Ab | Method and means for culturing osteoblastic cells |
| WO2009111022A1 (en) * | 2008-03-07 | 2009-09-11 | Corning Incorporated | Hydrophobically modified cellulose ether derivatives for cell culture and release |
| KR20120100962A (ko) | 2009-10-02 | 2012-09-12 | 박스터 헬쓰케어 에스.에이. | 신장 손상을 치료하는데 사용하기 위한 조혈 줄기 세포 |
| WO2012178215A1 (en) * | 2011-06-23 | 2012-12-27 | The Children's Hospital Of Philadelphia | Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof |
| WO2013126590A2 (en) | 2012-02-21 | 2013-08-29 | Baxter International Inc. | Pharmaceutical composition comprising cd34+ cells |
| EP3167911A1 (de) * | 2015-11-10 | 2017-05-17 | Oniris | In si-hpmc-eingekapselte insulinerzeugende zellen zur behandlung von typ-1-diabetes |
| WO2025117683A1 (en) * | 2023-11-29 | 2025-06-05 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Compositions and methods for chemical pancreatectomy for pancreas transplantation |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4038139A (en) * | 1976-07-16 | 1977-07-26 | G. D. Searle & Co., Limited | Cell culture medium |
| US4104124A (en) * | 1976-08-30 | 1978-08-01 | Louisiana State University Foundation | Process for the production of single cell protein and amino acids |
| DE2726313C3 (de) * | 1977-06-10 | 1980-02-07 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin |
| US4330622A (en) * | 1979-09-12 | 1982-05-18 | Becton Dickinson & Co. | Elimination of non-microbial turbidity in culture media |
| JPS56167624A (en) * | 1980-05-29 | 1981-12-23 | Toray Ind Inc | Method of interferon production |
| US5013714A (en) * | 1988-12-15 | 1991-05-07 | Lindstrom Richard L | Viscoelastic solution |
| DD282471A5 (de) * | 1989-04-21 | 1990-09-12 | Staatliches Inst Fuer Immunpra | Verfahren zur kultivation von mikroorganismen |
| JPH03175973A (ja) * | 1989-09-26 | 1991-07-31 | Kirin Brewery Co Ltd | 動物細胞培養用担体およびその製造法 |
| DE4115722A1 (de) * | 1991-05-14 | 1992-11-19 | Boehringer Mannheim Gmbh | Serumfreies medium zur kultivierung von saeugerzellen |
| IL102929A (en) * | 1992-08-24 | 1996-11-14 | Interpharm Lab Ltd | Serum-free medium for mammalian cells |
| US5834308A (en) * | 1994-04-28 | 1998-11-10 | University Of Florida Research Foundation, Inc. | In vitro growth of functional islets of Langerhans |
| US5587309A (en) * | 1994-04-29 | 1996-12-24 | The United States Of America As Represented By The Department Of Health And Human Services | Method of stimulating proliferation and differentiation of human fetal pancreatic cells ex vivo |
-
1997
- 1997-03-18 SE SE9700983A patent/SE9700983D0/xx unknown
-
1998
- 1998-03-16 WO PCT/SE1998/000475 patent/WO1998041617A1/en not_active Ceased
- 1998-03-16 DE DE69839393T patent/DE69839393T2/de not_active Expired - Lifetime
- 1998-03-16 JP JP54043798A patent/JP4237265B2/ja not_active Expired - Fee Related
- 1998-03-16 AT AT98909956T patent/ATE393214T1/de not_active IP Right Cessation
- 1998-03-16 EP EP98909956A patent/EP0975739B1/de not_active Expired - Lifetime
- 1998-03-16 CA CA002283676A patent/CA2283676C/en not_active Expired - Fee Related
- 1998-03-16 AU AU64313/98A patent/AU6431398A/en not_active Abandoned
- 1998-03-16 US US09/381,650 patent/US6479283B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2283676A1 (en) | 1998-09-24 |
| US6479283B1 (en) | 2002-11-12 |
| ATE393214T1 (de) | 2008-05-15 |
| CA2283676C (en) | 2004-11-02 |
| DE69839393T2 (de) | 2009-06-04 |
| JP2001521377A (ja) | 2001-11-06 |
| JP4237265B2 (ja) | 2009-03-11 |
| AU6431398A (en) | 1998-10-12 |
| EP0975739A1 (de) | 2000-02-02 |
| SE9700983D0 (sv) | 1997-03-18 |
| WO1998041617A1 (en) | 1998-09-24 |
| EP0975739B1 (de) | 2008-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| R079 | Amendment of ipc main class |
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