DE69833866D1 - Pharmazeutische zusammensetzungen mit neurotrophischen biologischen aktivität - Google Patents

Pharmazeutische zusammensetzungen mit neurotrophischen biologischen aktivität

Info

Publication number
DE69833866D1
DE69833866D1 DE69833866T DE69833866T DE69833866D1 DE 69833866 D1 DE69833866 D1 DE 69833866D1 DE 69833866 T DE69833866 T DE 69833866T DE 69833866 T DE69833866 T DE 69833866T DE 69833866 D1 DE69833866 D1 DE 69833866D1
Authority
DE
Germany
Prior art keywords
biological activity
neurotrophic
pharmaceutical compositions
binds
activates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69833866T
Other languages
English (en)
Inventor
Uri Saragovi
Sergei Maliartchouk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
McGill University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McGill University filed Critical McGill University
Application granted granted Critical
Publication of DE69833866D1 publication Critical patent/DE69833866D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DE69833866T 1997-08-05 1998-08-05 Pharmazeutische zusammensetzungen mit neurotrophischen biologischen aktivität Expired - Lifetime DE69833866D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002212315A CA2212315A1 (en) 1997-08-05 1997-08-05 Pharmaceutical composition with neurotrophic-like biological activity
PCT/CA1998/000749 WO1999007410A1 (en) 1997-08-05 1998-08-05 Pharmaceutical composition with neurotrophic-like biological activity

Publications (1)

Publication Number Publication Date
DE69833866D1 true DE69833866D1 (de) 2006-05-11

Family

ID=4161196

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69833866T Expired - Lifetime DE69833866D1 (de) 1997-08-05 1998-08-05 Pharmazeutische zusammensetzungen mit neurotrophischen biologischen aktivität

Country Status (8)

Country Link
EP (1) EP1001810B1 (de)
JP (1) JP2001513515A (de)
AT (1) ATE320268T1 (de)
AU (1) AU8724098A (de)
BR (1) BR9810977A (de)
CA (1) CA2212315A1 (de)
DE (1) DE69833866D1 (de)
WO (1) WO1999007410A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070694A2 (en) * 2001-03-01 2002-09-12 Mount Sinai Hospital Methods and compositions for modifying a receptor tyrosine kinase/protein tyrosine kinase signal to an apoptotic signal in a cell
BRPI0417270A (pt) * 2003-12-23 2007-03-27 Rinat Neuroscience Corp anticorpos agonistas antitrkc e métodos para utilização dos mesmos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5488099A (en) * 1992-03-06 1996-01-30 Persson, Deceased; Hakan B. Multifunctional chimeric neurotrophic factors
US5753225A (en) * 1993-12-03 1998-05-19 The Regents Of The University Of California Antibodies that mimic actions of neurotrophins
GB9525180D0 (en) * 1995-12-08 1996-02-07 Univ Mcgill Design of hormone-like antibodies with agonistic and antagonistic fuctions

Also Published As

Publication number Publication date
AU8724098A (en) 1999-03-01
ATE320268T1 (de) 2006-04-15
EP1001810A1 (de) 2000-05-24
CA2212315A1 (en) 1999-02-05
WO1999007410A1 (en) 1999-02-18
JP2001513515A (ja) 2001-09-04
EP1001810B1 (de) 2006-03-15
BR9810977A (pt) 2000-08-08

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Legal Events

Date Code Title Description
8332 No legal effect for de