DE69821978D1 - Mikronisierte bicyclische arzneistoffe enthaltende pharmazeutische zusammensetzungen - Google Patents
Mikronisierte bicyclische arzneistoffe enthaltende pharmazeutische zusammensetzungenInfo
- Publication number
- DE69821978D1 DE69821978D1 DE69821978T DE69821978T DE69821978D1 DE 69821978 D1 DE69821978 D1 DE 69821978D1 DE 69821978 T DE69821978 T DE 69821978T DE 69821978 T DE69821978 T DE 69821978T DE 69821978 D1 DE69821978 D1 DE 69821978D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical compositions
- containing pharmaceutical
- medicaments containing
- micronized
- bicyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C17/00—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
- B02C17/04—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls with unperforated container
- B02C17/06—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls with unperforated container with several compartments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C17/00—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
- B02C17/18—Details
- B02C17/20—Disintegrating members
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C17/00—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
- B02C17/18—Details
- B02C17/22—Lining for containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9726543 | 1997-12-16 | ||
GBGB9726543.3A GB9726543D0 (en) | 1997-12-16 | 1997-12-16 | Novel compositions |
PCT/EP1998/008156 WO1999030687A1 (en) | 1997-12-16 | 1998-12-14 | Pharmaceutical compositions containing micronized bicyclic drugs |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69821978D1 true DE69821978D1 (de) | 2004-04-01 |
DE69821978T2 DE69821978T2 (de) | 2004-12-23 |
Family
ID=10823680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69821978T Expired - Fee Related DE69821978T2 (de) | 1997-12-16 | 1998-12-14 | Mikronisierte bicyclische arzneistoffe enthaltende pharmazeutische zusammensetzungen |
Country Status (32)
Country | Link |
---|---|
EP (2) | EP1037612B1 (de) |
JP (1) | JP2002508310A (de) |
KR (1) | KR20010033149A (de) |
CN (2) | CN1475206A (de) |
AP (1) | AP2000001837A0 (de) |
AR (1) | AR017212A1 (de) |
AT (1) | ATE260094T1 (de) |
AU (1) | AU743155B2 (de) |
BG (1) | BG104596A (de) |
BR (1) | BR9813602A (de) |
CA (1) | CA2314968A1 (de) |
DE (1) | DE69821978T2 (de) |
DZ (1) | DZ2677A1 (de) |
EA (1) | EA003732B1 (de) |
ES (1) | ES2216350T3 (de) |
GB (1) | GB9726543D0 (de) |
HU (1) | HUP0100384A3 (de) |
ID (1) | ID24930A (de) |
IL (1) | IL136664A0 (de) |
MA (1) | MA24721A1 (de) |
MY (1) | MY132978A (de) |
NO (1) | NO20003073L (de) |
NZ (1) | NZ504991A (de) |
OA (1) | OA11429A (de) |
PE (1) | PE20000114A1 (de) |
PL (1) | PL341339A1 (de) |
SK (1) | SK9132000A3 (de) |
TR (1) | TR200001792T2 (de) |
TW (1) | TW200305442A (de) |
UY (1) | UY25307A1 (de) |
WO (1) | WO1999030687A1 (de) |
ZA (1) | ZA9811502B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2213638C (en) | 1995-02-24 | 2004-05-04 | Nanosystems L.L.C. | Aerosols containing nanoparticle dispersions |
US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
JP4188078B2 (ja) * | 2000-06-28 | 2008-11-26 | スミスクライン ビーチャム ピー エル シー | 湿式粉砕法 |
GB0112497D0 (en) * | 2001-05-22 | 2001-07-11 | Smithkline Beecham Plc | Formulation |
GB0127805D0 (en) | 2001-11-20 | 2002-01-09 | Smithkline Beecham Plc | Pharmaceutical composition |
EP1963018A2 (de) | 2005-11-10 | 2008-09-03 | The Lubrizol Corporation | Verfahren zur herstellung von dispersionen |
US20130281524A1 (en) * | 2008-06-05 | 2013-10-24 | Peter Blower | Novel treatments |
CA2726874A1 (en) * | 2008-06-05 | 2009-12-10 | Minster Research Limited | Novel treatments |
RU2012124838A (ru) * | 2009-12-03 | 2014-01-10 | Проксимэджен ЛТД | Лечение инфекционных заболеваний |
CA2782625A1 (en) * | 2009-12-03 | 2011-06-09 | Proximagen Ltd | Treatment of allodynia and hyperalgesia |
SI2471513T1 (sl) * | 2010-12-28 | 2015-10-30 | Lek Pharmaceuticals D.D. | Postopek za pripravo zdravilne učinkone (API) v obliki pelet |
WO2016157061A1 (en) * | 2015-03-31 | 2016-10-06 | Wockhardt Limited | Aseptic wet milling process for paliperidone palmitate |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5065946A (en) * | 1988-07-21 | 1991-11-19 | Matsushita Electric Industrial Co., Ltd. | Media agitating mill and method for milling ceramic powder |
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
AU660852B2 (en) * | 1992-11-25 | 1995-07-06 | Elan Pharma International Limited | Method of grinding pharmaceutical substances |
ES2143541T3 (es) * | 1992-12-11 | 2000-05-16 | Smithkline Beecham Plc | Composicion farmaceutica que contiene compuestos de tipo biciclico. |
CN1234702C (zh) * | 1994-06-10 | 2006-01-04 | 史密丝克莱恩比彻姆有限公司 | 苯并吡喃类化合物和包含它们的药物组合物 |
US5518738A (en) * | 1995-02-09 | 1996-05-21 | Nanosystem L.L.C. | Nanoparticulate nsaid compositions |
US5534270A (en) * | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
DE19614295A1 (de) * | 1995-04-21 | 1996-10-24 | Friedrich Dr Ing Vock | Verfahren und Vorrichtung zum Nassmahlen und Dispergieren von Feststoffpartikeln in Flüssigkeiten |
-
1997
- 1997-12-16 GB GBGB9726543.3A patent/GB9726543D0/en not_active Ceased
-
1998
- 1998-11-22 TW TW092109280A patent/TW200305442A/zh unknown
- 1998-12-14 BR BR9813602-0A patent/BR9813602A/pt not_active IP Right Cessation
- 1998-12-14 TR TR2000/01792T patent/TR200001792T2/xx unknown
- 1998-12-14 AT AT98966322T patent/ATE260094T1/de not_active IP Right Cessation
- 1998-12-14 EP EP98966322A patent/EP1037612B1/de not_active Expired - Lifetime
- 1998-12-14 SK SK913-2000A patent/SK9132000A3/sk unknown
- 1998-12-14 AU AU22724/99A patent/AU743155B2/en not_active Ceased
- 1998-12-14 PL PL98341339A patent/PL341339A1/xx unknown
- 1998-12-14 DE DE69821978T patent/DE69821978T2/de not_active Expired - Fee Related
- 1998-12-14 JP JP2000538670A patent/JP2002508310A/ja active Pending
- 1998-12-14 AP APAP/P/2000/001837A patent/AP2000001837A0/en unknown
- 1998-12-14 ID IDW20001124A patent/ID24930A/id unknown
- 1998-12-14 MA MA25390A patent/MA24721A1/fr unknown
- 1998-12-14 CA CA002314968A patent/CA2314968A1/en not_active Abandoned
- 1998-12-14 EP EP03076016A patent/EP1338274A1/de not_active Withdrawn
- 1998-12-14 ES ES98966322T patent/ES2216350T3/es not_active Expired - Lifetime
- 1998-12-14 KR KR1020007006525A patent/KR20010033149A/ko not_active Application Discontinuation
- 1998-12-14 EA EA200000664A patent/EA003732B1/ru not_active IP Right Cessation
- 1998-12-14 CN CNA031787088A patent/CN1475206A/zh active Pending
- 1998-12-14 NZ NZ504991A patent/NZ504991A/xx unknown
- 1998-12-14 IL IL13666498A patent/IL136664A0/xx unknown
- 1998-12-14 WO PCT/EP1998/008156 patent/WO1999030687A1/en not_active Application Discontinuation
- 1998-12-14 HU HU0100384A patent/HUP0100384A3/hu unknown
- 1998-12-14 CN CN98813568A patent/CN1284865A/zh active Pending
- 1998-12-15 MY MYPI98005667A patent/MY132978A/en unknown
- 1998-12-15 AR ARP980106367A patent/AR017212A1/es not_active Application Discontinuation
- 1998-12-15 DZ DZ980287A patent/DZ2677A1/xx active
- 1998-12-15 UY UY25307A patent/UY25307A1/es not_active Application Discontinuation
- 1998-12-15 ZA ZA9811502A patent/ZA9811502B/xx unknown
- 1998-12-16 PE PE1998001230A patent/PE20000114A1/es not_active Application Discontinuation
-
2000
- 2000-06-15 NO NO20003073A patent/NO20003073L/no not_active Application Discontinuation
- 2000-06-16 OA OA1200000176A patent/OA11429A/en unknown
- 2000-07-11 BG BG104596A patent/BG104596A/xx unknown
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