SI2471513T1 - Postopek za pripravo zdravilne učinkone (API) v obliki pelet - Google Patents

Postopek za pripravo zdravilne učinkone (API) v obliki pelet

Info

Publication number
SI2471513T1
SI2471513T1 SI201031017T SI201031017T SI2471513T1 SI 2471513 T1 SI2471513 T1 SI 2471513T1 SI 201031017 T SI201031017 T SI 201031017T SI 201031017 T SI201031017 T SI 201031017T SI 2471513 T1 SI2471513 T1 SI 2471513T1
Authority
SI
Slovenia
Prior art keywords
api
beads
producing
preparation
active pharmaceutical
Prior art date
Application number
SI201031017T
Other languages
English (en)
Inventor
Miha Homar
Matej Horvat
Mateja Cegnar
Janez Kerc
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of SI2471513T1 publication Critical patent/SI2471513T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
SI201031017T 2010-12-28 2010-12-28 Postopek za pripravo zdravilne učinkone (API) v obliki pelet SI2471513T1 (sl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10016118.1A EP2471513B1 (en) 2010-12-28 2010-12-28 Process for producing an active pharmaceutical ingredient (API) preparation in the form of beads

Publications (1)

Publication Number Publication Date
SI2471513T1 true SI2471513T1 (sl) 2015-10-30

Family

ID=44063846

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201031017T SI2471513T1 (sl) 2010-12-28 2010-12-28 Postopek za pripravo zdravilne učinkone (API) v obliki pelet

Country Status (2)

Country Link
EP (1) EP2471513B1 (sl)
SI (1) SI2471513T1 (sl)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726543D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel compositions
GB0112497D0 (en) * 2001-05-22 2001-07-11 Smithkline Beecham Plc Formulation
EP1498116A1 (en) * 2002-03-20 2005-01-19 Hosokawa Micron Corporation Method of manufacturing chemical-containing composite particles

Also Published As

Publication number Publication date
EP2471513B1 (en) 2015-06-10
EP2471513A1 (en) 2012-07-04

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SI2471513T1 (sl) Postopek za pripravo zdravilne učinkone (API) v obliki pelet