DE69820244D1 - Trans-platinverbindung und diagnostischer testsatz - Google Patents

Trans-platinverbindung und diagnostischer testsatz

Info

Publication number
DE69820244D1
DE69820244D1 DE69820244T DE69820244T DE69820244D1 DE 69820244 D1 DE69820244 D1 DE 69820244D1 DE 69820244 T DE69820244 T DE 69820244T DE 69820244 T DE69820244 T DE 69820244T DE 69820244 D1 DE69820244 D1 DE 69820244D1
Authority
DE
Germany
Prior art keywords
trans
test set
diagnostic test
platinum connection
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69820244T
Other languages
English (en)
Other versions
DE69820244T2 (de
Inventor
Jan Houthoff
Jan Reedijk
H Volkers
Jochem Heetebrij
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kreatech Biotechnology BV
Original Assignee
Kreatech Biotechnology BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotechnology BV filed Critical Kreatech Biotechnology BV
Priority claimed from PCT/NL1998/000206 external-priority patent/WO1998045304A1/en
Application granted granted Critical
Publication of DE69820244D1 publication Critical patent/DE69820244D1/de
Publication of DE69820244T2 publication Critical patent/DE69820244T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Interface Circuits In Exchanges (AREA)
DE69820244T 1997-04-10 1998-04-09 Trans-platinverbindung und diagnostischer testsatz Expired - Lifetime DE69820244T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97201066A EP0870770A1 (de) 1997-04-10 1997-04-10 Trans-Platinverbindung, ein diese enthaltender, diagnostischer Kit, und ein Verfahren zur Markierung von bioorganischen Molekülen
EP97201066 1997-04-10
PCT/NL1998/000206 WO1998045304A1 (en) 1997-04-10 1998-04-09 Trans-platinum compound, and diagnostic kit

Publications (2)

Publication Number Publication Date
DE69820244D1 true DE69820244D1 (de) 2004-01-15
DE69820244T2 DE69820244T2 (de) 2004-09-09

Family

ID=8228196

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69820244T Expired - Lifetime DE69820244T2 (de) 1997-04-10 1998-04-09 Trans-platinverbindung und diagnostischer testsatz

Country Status (11)

Country Link
US (1) US6248531B1 (de)
EP (1) EP0870770A1 (de)
JP (1) JP4212652B2 (de)
AT (1) ATE255587T1 (de)
AU (1) AU737441B2 (de)
CA (1) CA2286668C (de)
DE (1) DE69820244T2 (de)
DK (1) DK0973785T3 (de)
ES (1) ES2212279T3 (de)
NZ (1) NZ500184A (de)
PT (1) PT973785E (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002213125B2 (en) * 2000-10-11 2007-11-22 Applied Biosystems, Llc. Fluorescent nucleobase conjugates having anionic linkers
WO2004027384A2 (en) * 2002-09-17 2004-04-01 Perkinelmer Life Sciences, Inc. Real-time detection of nucleic acid reactions
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
CA2531123A1 (en) * 2003-07-02 2005-01-13 Perkinelmer Las, Inc. Assay and process for labeling and detection of micro rna and small interfering rna sequences
EP1669760A1 (de) * 2004-12-08 2006-06-14 Kreatech Biotechnology B.V. Markierte Übergangsmetall-Komplexe
EP1745802A1 (de) * 2005-07-20 2007-01-24 Kreatech Biotechnology B.V. Verfahren zur Konjugierung therapeutischer Verbindungen an zellgezielten Gruppen über Metallkomplexen
JP6120416B2 (ja) 2012-01-06 2017-04-26 リンクシス ビー．ヴイ． 細胞標的コンジュゲートを調製するための方法、及び得られる錯体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5107007A (en) * 1989-09-01 1992-04-21 The University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
US5624919A (en) * 1993-09-14 1997-04-29 The University Of Vermont And State Agricultural College Trans platinum (IV) complexes
US5521289A (en) * 1994-07-29 1996-05-28 Nanoprobes, Inc. Small organometallic probes
ATE246696T1 (de) * 1995-05-09 2003-08-15 Kreatech Biotech Bv Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzen

Also Published As

Publication number Publication date
CA2286668C (en) 2008-05-06
DE69820244T2 (de) 2004-09-09
CA2286668A1 (en) 1998-10-15
US6248531B1 (en) 2001-06-19
NZ500184A (en) 2001-08-31
DK0973785T3 (da) 2004-04-05
ATE255587T1 (de) 2003-12-15
JP2001521511A (ja) 2001-11-06
JP4212652B2 (ja) 2009-01-21
AU737441B2 (en) 2001-08-16
EP0870770A1 (de) 1998-10-14
PT973785E (pt) 2004-04-30
AU6751798A (en) 1998-10-30
ES2212279T3 (es) 2004-07-16

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Legal Events

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8364 No opposition during term of opposition