PT973785E - Composto de trans-platina e estojo de diagnostico - Google Patents

Composto de trans-platina e estojo de diagnostico

Info

Publication number
PT973785E
PT973785E PT98912826T PT98912826T PT973785E PT 973785 E PT973785 E PT 973785E PT 98912826 T PT98912826 T PT 98912826T PT 98912826 T PT98912826 T PT 98912826T PT 973785 E PT973785 E PT 973785E
Authority
PT
Portugal
Prior art keywords
trans
platinum composite
diagnostic case
bio
attachment
Prior art date
Application number
PT98912826T
Other languages
English (en)
Inventor
Hendrik Jan Houthoff
Jan Reedijk
Herman H Volkers
Robert Jochem Heetebrij
Original Assignee
Kreatech Biotech Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotech Bv filed Critical Kreatech Biotech Bv
Priority claimed from PCT/NL1998/000206 external-priority patent/WO1998045304A1/en
Publication of PT973785E publication Critical patent/PT973785E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Interface Circuits In Exchanges (AREA)
PT98912826T 1997-04-10 1998-04-09 Composto de trans-platina e estojo de diagnostico PT973785E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201066A EP0870770A1 (en) 1997-04-10 1997-04-10 A trans-platinum based compound, a diagnostic kit comprising said compound and a method for labeling a bio-organic molecule wherein use is made of said compound
PCT/NL1998/000206 WO1998045304A1 (en) 1997-04-10 1998-04-09 Trans-platinum compound, and diagnostic kit

Publications (1)

Publication Number Publication Date
PT973785E true PT973785E (pt) 2004-04-30

Family

ID=8228196

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98912826T PT973785E (pt) 1997-04-10 1998-04-09 Composto de trans-platina e estojo de diagnostico

Country Status (11)

Country Link
US (1) US6248531B1 (pt)
EP (1) EP0870770A1 (pt)
JP (1) JP4212652B2 (pt)
AT (1) ATE255587T1 (pt)
AU (1) AU737441B2 (pt)
CA (1) CA2286668C (pt)
DE (1) DE69820244T2 (pt)
DK (1) DK0973785T3 (pt)
ES (1) ES2212279T3 (pt)
NZ (1) NZ500184A (pt)
PT (1) PT973785E (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1312502A (en) * 2000-10-11 2002-04-22 Pe Corp Ny Fluorescent nucleobase conjugates having anionic linkers
US20050208495A1 (en) * 2002-09-17 2005-09-22 Joseph Richard A Real-time detection of nucleic acid reactions
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
CA2531123A1 (en) * 2003-07-02 2005-01-13 Perkinelmer Las, Inc. Assay and process for labeling and detection of micro rna and small interfering rna sequences
EP1669760A1 (en) 2004-12-08 2006-06-14 Kreatech Biotechnology B.V. Labeled transition metal complexes
EP1745802A1 (en) * 2005-07-20 2007-01-24 Kreatech Biotechnology B.V. Method of conjugating therapeutic compounds to cell targeting moieties via metal complexes
US10668162B2 (en) 2012-01-06 2020-06-02 Linxis B.V. Method for preparing cell targeting conjugates, and the complexes obtained

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5107007A (en) * 1989-09-01 1992-04-21 The University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
US5624919A (en) * 1993-09-14 1997-04-29 The University Of Vermont And State Agricultural College Trans platinum (IV) complexes
US5521289A (en) * 1994-07-29 1996-05-28 Nanoprobes, Inc. Small organometallic probes
WO1996035696A1 (en) * 1995-05-09 1996-11-14 Kreatech Biotechnology B.V. Methods for the production of platinum-based linkers between labels and bio-organic molecules, for labelling bio-organic molecules, for detecting biological substances of interest and diagnostic test kits

Also Published As

Publication number Publication date
DE69820244T2 (de) 2004-09-09
DE69820244D1 (de) 2004-01-15
NZ500184A (en) 2001-08-31
ES2212279T3 (es) 2004-07-16
EP0870770A1 (en) 1998-10-14
CA2286668C (en) 2008-05-06
CA2286668A1 (en) 1998-10-15
DK0973785T3 (da) 2004-04-05
AU6751798A (en) 1998-10-30
ATE255587T1 (de) 2003-12-15
JP4212652B2 (ja) 2009-01-21
AU737441B2 (en) 2001-08-16
US6248531B1 (en) 2001-06-19
JP2001521511A (ja) 2001-11-06

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