DE69815311D1 - Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii - Google Patents

Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii

Info

Publication number
DE69815311D1
DE69815311D1 DE69815311T DE69815311T DE69815311D1 DE 69815311 D1 DE69815311 D1 DE 69815311D1 DE 69815311 T DE69815311 T DE 69815311T DE 69815311 T DE69815311 T DE 69815311T DE 69815311 D1 DE69815311 D1 DE 69815311D1
Authority
DE
Germany
Prior art keywords
benzosulphonamides
inhibitors
substituted derivatives
enzyme cyclooxygenase
cyclooxygenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69815311T
Other languages
English (en)
Inventor
Michael Hartmann
Peter Kremminger
Heinz Blaschke
Dagmar Stimmeder
Harald Fellier
Franz Rovenszky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Austria GmbH
Original Assignee
Nycomed Austria GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Austria GmbH filed Critical Nycomed Austria GmbH
Application granted granted Critical
Publication of DE69815311D1 publication Critical patent/DE69815311D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69815311T 1997-02-03 1998-02-03 Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii Expired - Lifetime DE69815311D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0016597A ATA16597A (de) 1997-02-03 1997-02-03 Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide
PCT/GB1998/000342 WO1998033769A1 (en) 1997-02-03 1998-02-03 Substituted derivatives of benzosulphonamides as inhibitors of the enzyme cyclooxygenase ii

Publications (1)

Publication Number Publication Date
DE69815311D1 true DE69815311D1 (de) 2003-07-10

Family

ID=3483303

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69815311T Expired - Lifetime DE69815311D1 (de) 1997-02-03 1998-02-03 Substituierte derivate von benzosulphonamiden als hemmer des enzym cyclooxygenase ii

Country Status (7)

Country Link
US (1) US6297282B1 (de)
EP (1) EP0968180B1 (de)
JP (1) JP2001509800A (de)
AT (2) ATA16597A (de)
AU (1) AU5875498A (de)
DE (1) DE69815311D1 (de)
WO (1) WO1998033769A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
US6649645B1 (en) * 1998-12-23 2003-11-18 Pharmacia Corporation Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
US7067539B2 (en) 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
US7507767B2 (en) 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
US20060167074A1 (en) * 2001-06-19 2006-07-27 Norbert Muller Methods and compositions for the treatment of psychiatric disorders
DE10129320A1 (de) * 2001-06-19 2003-04-10 Norbert Mueller Verwendung von COX-2 Inhibitoren zur Behandlung von Schizophrenie, wahnhaften Störungen, affektiven Störungen oder Ticstörungen
HUP0401924A3 (en) 2001-11-14 2009-07-28 Schering Corp Cannabinoid receptor ligands, their use and pharmaceutical compositions containing them
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
CN1662496A (zh) 2002-06-19 2005-08-31 先灵公司 大麻素受体激动剂
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
ES2341240T3 (es) 2002-12-13 2010-06-17 Warner-Lambert Company Llc Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior.
AR043633A1 (es) 2003-03-20 2005-08-03 Schering Corp Ligandos de receptores de canabinoides
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
JP4354984B2 (ja) 2003-05-07 2009-10-28 オステオロジックス エイ／エス 水溶性ストロンチウム塩を用いる軟骨／骨症状の治療
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
WO2005023189A2 (en) * 2003-09-03 2005-03-17 Pharmacia Corporation Method of cox-2 selective inhibitor and nitric oxide-donating agent
EP1708718A1 (de) 2004-01-22 2006-10-11 Pfizer Limited Triazol-derivate zur hemmung der vasopressing-antagonistischen aktivität
WO2005105779A1 (en) * 2004-04-28 2005-11-10 Pfizer Limited 3-heterocyclyl-4-phenyl-triazole derivatives as inhibitors of the vasopressin v1a receptor
AU2006244393B2 (en) * 2005-05-05 2012-06-21 Cook Biotech Incorporated Implantable materials and methods for inhibiting tissue adhesion formation
CN101600458A (zh) 2006-12-22 2009-12-09 瑞蔻达蒂爱尔兰有限公司 采用α2δ配体和NSAID的下泌尿道疾病的联合治疗
US8815828B2 (en) * 2008-07-02 2014-08-26 University Of Florida Research Foundation, Inc. Therapeutic combinations for use in neoplasia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604260A (en) * 1992-12-11 1997-02-18 Merck Frosst Canada Inc. 5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
JPH11510485A (ja) * 1995-07-21 1999-09-14 ニィコメド・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 酵素のシクロオキシゲナーゼｉｉの阻害剤としてのベンゼンスルホンアミドの誘導体
DE19533644A1 (de) * 1995-09-12 1997-03-13 Nycomed Arzneimittel Gmbh Neue Benzolsulfonamide
US6146615A (en) * 1999-01-11 2000-11-14 The University Of Toledo Contrast agents for image enhancement in magnetic resonance imaging

Also Published As

Publication number Publication date
EP0968180B1 (de) 2003-06-04
ATE242206T1 (de) 2003-06-15
AU5875498A (en) 1998-08-25
WO1998033769A1 (en) 1998-08-06
US6297282B1 (en) 2001-10-02
JP2001509800A (ja) 2001-07-24
EP0968180A1 (de) 2000-01-05
ATA16597A (de) 1998-04-15

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Legal Events

Date Code Title Description
8332 No legal effect for de