DE69813553D1 - Anwendung von akustooptischen und sonolumineszenten kontrastmitteln in diagnostischen verfahren - Google Patents
Anwendung von akustooptischen und sonolumineszenten kontrastmitteln in diagnostischen verfahrenInfo
- Publication number
- DE69813553D1 DE69813553D1 DE69813553T DE69813553T DE69813553D1 DE 69813553 D1 DE69813553 D1 DE 69813553D1 DE 69813553 T DE69813553 T DE 69813553T DE 69813553 T DE69813553 T DE 69813553T DE 69813553 D1 DE69813553 D1 DE 69813553D1
- Authority
- DE
- Germany
- Prior art keywords
- acustooptic
- sonoluminescent
- application
- contrast agents
- diagnostic procedures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002872 contrast media Substances 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 238000002604 ultrasonography Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
- A61K49/0043—Fluorescein, used in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
- A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
- A61K49/0078—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion microemulsion, nanoemulsion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
- A61K49/0084—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0089—Particulate, powder, adsorbate, bead, sphere
- A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
- A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
- A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Nanotechnology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Semiconductor Lasers (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9712525.6A GB9712525D0 (en) | 1997-06-16 | 1997-06-16 | Method |
GB9712525 | 1997-06-16 | ||
PCT/GB1998/001438 WO1998057666A1 (en) | 1997-06-16 | 1998-05-19 | Use of acousto-optical and sonoluminescence contrast agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69813553D1 true DE69813553D1 (de) | 2003-05-22 |
DE69813553T2 DE69813553T2 (de) | 2004-03-04 |
Family
ID=10814250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69813553T Expired - Lifetime DE69813553T2 (de) | 1997-06-16 | 1998-05-19 | Anwendung von akustooptischen und sonolumineszenten kontrastmitteln in diagnostischen verfahren |
Country Status (10)
Country | Link |
---|---|
US (1) | US6424857B1 (de) |
EP (1) | EP0991429B1 (de) |
JP (1) | JP2002504924A (de) |
AT (1) | ATE237363T1 (de) |
AU (1) | AU7443398A (de) |
DE (1) | DE69813553T2 (de) |
ES (1) | ES2196558T3 (de) |
GB (1) | GB9712525D0 (de) |
PT (1) | PT991429E (de) |
WO (1) | WO1998057666A1 (de) |
Families Citing this family (70)
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GB9710049D0 (en) * | 1997-05-19 | 1997-07-09 | Nycomed Imaging As | Method |
US8668737B2 (en) | 1997-10-10 | 2014-03-11 | Senorx, Inc. | Tissue marking implant |
US7637948B2 (en) | 1997-10-10 | 2009-12-29 | Senorx, Inc. | Tissue marking implant |
US6725083B1 (en) | 1999-02-02 | 2004-04-20 | Senorx, Inc. | Tissue site markers for in VIVO imaging |
US7983734B2 (en) | 2003-05-23 | 2011-07-19 | Senorx, Inc. | Fibrous marker and intracorporeal delivery thereof |
US6862470B2 (en) | 1999-02-02 | 2005-03-01 | Senorx, Inc. | Cavity-filling biopsy site markers |
US9820824B2 (en) | 1999-02-02 | 2017-11-21 | Senorx, Inc. | Deployment of polysaccharide markers for treating a site within a patent |
US8361082B2 (en) | 1999-02-02 | 2013-01-29 | Senorx, Inc. | Marker delivery device with releasable plug |
US20090030309A1 (en) | 2007-07-26 | 2009-01-29 | Senorx, Inc. | Deployment of polysaccharide markers |
US7651505B2 (en) | 2002-06-17 | 2010-01-26 | Senorx, Inc. | Plugged tip delivery for marker placement |
US8498693B2 (en) | 1999-02-02 | 2013-07-30 | Senorx, Inc. | Intracorporeal marker and marker delivery device |
US6575991B1 (en) | 1999-06-17 | 2003-06-10 | Inrad, Inc. | Apparatus for the percutaneous marking of a lesion |
ES2409758T3 (es) | 2000-11-20 | 2013-06-27 | Senorx, Inc. | Marcadores de sitios tisulares para formación de imagen in vivo |
US6984373B2 (en) | 2000-12-23 | 2006-01-10 | Dyax Corp. | Fibrin binding moieties useful as imaging agents |
US20030200932A1 (en) | 2001-02-16 | 2003-10-30 | Toelken L. Taizo | Ultrasound quality inspection of avian eggs |
US6512839B1 (en) * | 2001-02-21 | 2003-01-28 | Ultra-Hatch, Inc. | Ultrasound sex determination of avian hatchlings |
US7474906B2 (en) * | 2001-05-22 | 2009-01-06 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Method for dye injection for the transcutaneous measurement of cardiac output |
US6757554B2 (en) * | 2001-05-22 | 2004-06-29 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution |
US20080027298A1 (en) * | 2001-05-22 | 2008-01-31 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern Californ | System for Repetitive Measurements of Cardiac Output in Freely Moving Individuals |
US8337444B2 (en) * | 2001-05-22 | 2012-12-25 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution for hemodialysis |
US7354401B1 (en) | 2002-06-19 | 2008-04-08 | Toelken L Taizo | Ultrasound sex determination for sorting of avian hatchlings |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
WO2004065621A1 (en) | 2002-03-01 | 2004-08-05 | Dyax Corp. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
AU2003213730A1 (en) | 2002-03-01 | 2003-09-16 | Bracco International B.V. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
US20030178616A1 (en) * | 2002-03-25 | 2003-09-25 | Prevenslik Thomas V. | Cavity QED devices |
US20060036158A1 (en) | 2003-11-17 | 2006-02-16 | Inrad, Inc. | Self-contained, self-piercing, side-expelling marking apparatus |
US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
WO2004064751A2 (en) * | 2003-01-16 | 2004-08-05 | St. Johns University New York | Nanoparticle based stabilization of ir fluorescent dyes |
US7378081B2 (en) | 2003-01-29 | 2008-05-27 | Vincon Research Enterprises, Llc | Composition and method for direct visualization of the human appendix |
EP2284180B1 (de) | 2003-03-03 | 2015-09-09 | Dyax Corp. | Verwendungen von Spezifisch an HGF-Rezeptor (cMET) bindenden Peptiden |
US7877133B2 (en) | 2003-05-23 | 2011-01-25 | Senorx, Inc. | Marker or filler forming fluid |
US20050107694A1 (en) * | 2003-11-17 | 2005-05-19 | Jansen Floribertus H. | Method and system for ultrasonic tagging of fluorescence |
US20050273002A1 (en) | 2004-06-04 | 2005-12-08 | Goosen Ryan L | Multi-mode imaging marker |
JP4578817B2 (ja) * | 2004-02-06 | 2010-11-10 | オリンパス株式会社 | 外科手術用病変部同定システム |
CN101019028B (zh) * | 2004-09-10 | 2013-05-01 | 皇家飞利浦电子股份有限公司 | 用于组合的光学-超声成像的化合物和方法 |
US20210299056A9 (en) | 2004-10-25 | 2021-09-30 | Varian Medical Systems, Inc. | Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods |
JP5080989B2 (ja) | 2005-02-23 | 2012-11-21 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 関心物体の撮像 |
US10357328B2 (en) | 2005-04-20 | 2019-07-23 | Bard Peripheral Vascular, Inc. and Bard Shannon Limited | Marking device with retractable cannula |
CA2562580C (en) | 2005-10-07 | 2014-04-29 | Inrad, Inc. | Drug-eluting tissue marker |
WO2007067978A1 (en) * | 2005-12-09 | 2007-06-14 | Invitrogen Corporation | Optical in vivo imaging contrast agents and methods of use |
EP1981401A4 (de) | 2006-01-20 | 2010-07-21 | Alfred E Mann Inst Biomed Eng | Messung von herzminutenvolumen und blutvolumen durch nichtinvasive erfassung von indikatorverdünnung |
FR2900043B1 (fr) * | 2006-04-24 | 2008-07-04 | Commissariat Energie Atomique | Procede d'imagerie optique par fluorescence de tissus biologiques, notamment pour delimiter des regions d'interet des tissus a analyser par tomographie |
US20070297988A1 (en) * | 2006-06-21 | 2007-12-27 | Bin Wu | Optical probes for in vivo imaging |
US20080294039A1 (en) * | 2006-08-04 | 2008-11-27 | Senorx, Inc. | Assembly with hemostatic and radiographically detectable pellets |
EP2079385B1 (de) | 2006-10-23 | 2013-11-20 | C.R.Bard, Inc. | Brustkennzeichner |
US9579077B2 (en) | 2006-12-12 | 2017-02-28 | C.R. Bard, Inc. | Multiple imaging mode tissue marker |
ES2432572T3 (es) | 2006-12-18 | 2013-12-04 | C.R. Bard, Inc. | Marcador de biopsia con propiedades de obtención de imágenes generadas in situ |
KR101506557B1 (ko) * | 2007-07-25 | 2015-03-30 | 셀로노바 바이오사이언시즈, 인코포레이티드 | 치료 및/또는 진단 응용을 위한 컬러-코드화되고 크기별로 나뉜 적재가능한 중합체 입자 및 그의 제조방법 및 사용방법 |
EP2036577A1 (de) * | 2007-09-14 | 2009-03-18 | mivenion GmbH | Diagnostische Stoffe für die optische bildgebende Untersuchung auf der Basis von nanopartikulären Formulierungen |
EP2476703A1 (de) | 2011-01-14 | 2012-07-18 | Bracco Imaging S.p.A | Mit einem Bakterium kreuzreagierende menschliche Antikörper und ein Autoantigen aus atherosklerotischen Plaques |
WO2009061769A1 (en) * | 2007-11-06 | 2009-05-14 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern Califorina | Measurement of hematocrit and cardiac output from optical transmission and reflection changes |
WO2009099767A2 (en) | 2008-01-31 | 2009-08-13 | C.R. Bard, Inc. | Biopsy tissue marker |
EP2147684A1 (de) | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Selektiv gegen Metallproteasen wirkende Diagnosemittel |
FR2934954B1 (fr) | 2008-08-14 | 2011-07-22 | Commissariat Energie Atomique | Emulsion fluorescente de vert d'indocyanine |
FR2934953B1 (fr) | 2008-08-14 | 2011-01-21 | Commissariat Energie Atomique | Nanoemulsions de nanocristaux |
FR2934955B1 (fr) | 2008-08-14 | 2011-07-08 | Commissariat Energie Atomique | Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions |
US9327061B2 (en) | 2008-09-23 | 2016-05-03 | Senorx, Inc. | Porous bioabsorbable implant |
WO2010077244A1 (en) | 2008-12-30 | 2010-07-08 | C.R. Bard Inc. | Marker delivery device for tissue marker placement |
WO2012095516A1 (en) | 2011-01-14 | 2012-07-19 | Bracco Imaging Spa | Human antibodies cross-reacting with a bacterial and a self antigen from atherosclerotic plaques |
US9138492B2 (en) | 2012-02-23 | 2015-09-22 | Canon Kabushiki Kaisha | Particle containing hydrophobic dye having cyanine structure, and contrast agent containing the particle |
US8917442B2 (en) | 2012-09-20 | 2014-12-23 | Elwha Llc | Focusing electromagnetic radiation within a turbid medium using ultrasonic modulation |
US9232896B2 (en) | 2012-09-20 | 2016-01-12 | Elwha Llc | Focusing electromagnetic radiation within a turbid medium using ultrasonic modulation |
US10471163B2 (en) | 2013-09-13 | 2019-11-12 | The General Hospital Corporation | Activatable fibrin-binding probes |
USD715442S1 (en) | 2013-09-24 | 2014-10-14 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
USD716451S1 (en) | 2013-09-24 | 2014-10-28 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
USD716450S1 (en) | 2013-09-24 | 2014-10-28 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
USD715942S1 (en) | 2013-09-24 | 2014-10-21 | C. R. Bard, Inc. | Tissue marker for intracorporeal site identification |
IT202100005123A1 (it) | 2021-03-04 | 2022-09-04 | Torino Politecnico | Metodo ed apparato per immagine di contrasto in sonoluminescenza assistita da nanoparticelle in ambito medico diagnostico, in particolare oncologico |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4948975A (en) * | 1988-09-08 | 1990-08-14 | The United States Of America As Represented By The Secretary Of The Air Force | Quantitative luminescence imaging system |
CA2087412A1 (en) * | 1992-01-17 | 1993-07-18 | Joseph R. Lakowicz | Ph and pco2 sensing by luminescent lifetimes and energy transfer |
US5491344A (en) * | 1993-12-01 | 1996-02-13 | Tufts University | Method and system for examining the composition of a fluid or solid sample using fluorescence and/or absorption spectroscopy |
US5659173A (en) * | 1994-02-23 | 1997-08-19 | The Regents Of The University Of California | Converting acoustic energy into useful other energy forms |
GB9502065D0 (en) * | 1995-02-02 | 1995-03-22 | Nycomed Imaging As | Contrast media |
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1997
- 1997-06-16 GB GBGB9712525.6A patent/GB9712525D0/en active Pending
-
1998
- 1998-05-19 AT AT98921652T patent/ATE237363T1/de not_active IP Right Cessation
- 1998-05-19 EP EP98921652A patent/EP0991429B1/de not_active Expired - Lifetime
- 1998-05-19 AU AU74433/98A patent/AU7443398A/en not_active Abandoned
- 1998-05-19 ES ES98921652T patent/ES2196558T3/es not_active Expired - Lifetime
- 1998-05-19 WO PCT/GB1998/001438 patent/WO1998057666A1/en active IP Right Grant
- 1998-05-19 DE DE69813553T patent/DE69813553T2/de not_active Expired - Lifetime
- 1998-06-15 PT PT98921652T patent/PT991429E/pt unknown
- 1998-06-15 JP JP50392299A patent/JP2002504924A/ja active Pending
-
1999
- 1999-12-10 US US09/458,007 patent/US6424857B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7443398A (en) | 1999-01-04 |
ES2196558T3 (es) | 2003-12-16 |
DE69813553T2 (de) | 2004-03-04 |
ATE237363T1 (de) | 2003-05-15 |
EP0991429A1 (de) | 2000-04-12 |
EP0991429B1 (de) | 2003-04-16 |
JP2002504924A (ja) | 2002-02-12 |
GB9712525D0 (en) | 1997-08-20 |
US6424857B1 (en) | 2002-07-23 |
WO1998057666A1 (en) | 1998-12-23 |
WO1998057666A8 (en) | 2000-01-20 |
PT991429E (pt) | 2003-09-30 |
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