DE69807687T2 - Transgenfisch mit gewebespezifischer expression - Google Patents

Transgenfisch mit gewebespezifischer expression

Info

Publication number
DE69807687T2
DE69807687T2 DE69807687T DE69807687T DE69807687T2 DE 69807687 T2 DE69807687 T2 DE 69807687T2 DE 69807687 T DE69807687 T DE 69807687T DE 69807687 T DE69807687 T DE 69807687T DE 69807687 T2 DE69807687 T2 DE 69807687T2
Authority
DE
Germany
Prior art keywords
transgenic fish
fish
tissue
specific
specific expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69807687T
Other languages
English (en)
Other versions
DE69807687D1 (de
Inventor
Shuo Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Augusta University Research Institute Inc
Original Assignee
Medical College of Georgia Research Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25358056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69807687(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medical College of Georgia Research Institute Inc filed Critical Medical College of Georgia Research Institute Inc
Application granted granted Critical
Publication of DE69807687D1 publication Critical patent/DE69807687D1/de
Publication of DE69807687T2 publication Critical patent/DE69807687T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/40—Fish
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Multicomponent Fibers (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DE69807687T 1997-06-09 1998-06-09 Transgenfisch mit gewebespezifischer expression Expired - Fee Related DE69807687T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/871,755 US6380458B1 (en) 1997-06-09 1997-06-09 Cell-lineage specific expression in transgenic zebrafish
PCT/US1998/011808 WO1998056902A2 (en) 1997-06-09 1998-06-09 Transgenic fish with tissue-specific expression

Publications (2)

Publication Number Publication Date
DE69807687D1 DE69807687D1 (de) 2002-10-10
DE69807687T2 true DE69807687T2 (de) 2003-01-02

Family

ID=25358056

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69807687T Expired - Fee Related DE69807687T2 (de) 1997-06-09 1998-06-09 Transgenfisch mit gewebespezifischer expression

Country Status (11)

Country Link
US (3) US6380458B1 (de)
EP (2) EP1240824A1 (de)
JP (1) JP2002504821A (de)
AT (1) ATE223483T1 (de)
AU (1) AU754993B2 (de)
CA (1) CA2293722A1 (de)
DE (1) DE69807687T2 (de)
DK (1) DK0986640T3 (de)
ES (1) ES2179512T3 (de)
PT (1) PT986640E (de)
WO (1) WO1998056902A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6380458B1 (en) * 1997-06-09 2002-04-30 Medical College Of Georgia Research Institute, Inc. Cell-lineage specific expression in transgenic zebrafish
AU749688B2 (en) * 1998-02-23 2002-07-04 Phylonix Pharmaceuticals, Inc. Methods of screening agents for activity using teleosts
US6656449B1 (en) * 1998-02-23 2003-12-02 Phylonix Pharmaceuticals, Inc. Methods of screening agents for activity using teleosts
US7951989B2 (en) * 1998-02-23 2011-05-31 Phylonix Pharmaceuticals, Inc. Methods of screening agents for activity using teleosts
WO2000049150A1 (en) * 1999-02-18 2000-08-24 National University Of Singapore Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
SG82624A1 (en) * 1999-02-18 2001-08-21 Univ Singapore Chimeric gene constructs for generation of fluorescent transgenic ornamental fish
DE60137501D1 (de) * 2000-03-17 2009-03-12 Anticancer Inc Optisches abbildungssystem zur darstellung der genexpression des gesamten körpers und anwendungen
JP3354918B2 (ja) * 2000-06-08 2002-12-09 佑子 若松 透明メダカ
AU2002221731A1 (en) * 2000-10-23 2002-05-06 Mermaid Pharmaceuticals Gmbh Method for generating transgenic fish embryos using an episomal vector system
WO2002081680A1 (en) * 2001-04-05 2002-10-17 Institute Of Molecular Agrobiology Method for producing transgenic teleost fish
WO2003007800A2 (en) * 2001-07-17 2003-01-30 The General Hospital Corporation Methods for diagnosing and treating diseases and conditions of the digestive system and cancer
US7491810B2 (en) * 2001-11-30 2009-02-17 U.S. Department Of Veterans Affairs Transgenic screen and method for screening modulators of brain-derived neurotrophic factor (BDNF) production
US7615676B2 (en) * 2001-11-30 2009-11-10 U.S. Department Of Veterans Affairs Transgenic screen and method for screening modulators of brain-derived neurotrophic factor (BDNF) production
GB2382579B (en) * 2001-11-30 2003-11-12 Daniolabs Ltd Disease models, assays, methods and means
CA2477624A1 (en) * 2002-02-28 2003-09-04 Zygogen, Llc Transgenic zebrafish models for thrombosis
US7332647B2 (en) * 2002-06-11 2008-02-19 The Regents Of The University Of California Fish produced by nuclear transfer from cultured cells
US7465848B2 (en) * 2002-11-20 2008-12-16 The General Hospital Corporation Zebrafish assay
US20040133114A1 (en) * 2002-11-20 2004-07-08 Macrae Calum A. Zebrafish Assay
GB0228093D0 (en) * 2002-12-02 2003-01-08 Daniolabs Ltd Disease models and uses thereof
US20040194156A1 (en) * 2002-12-27 2004-09-30 Califa Llc Transgenic aquatic invertebrates as a bioreactor for production of recombinant polypeptides
US20050034677A1 (en) * 2003-07-25 2005-02-17 Alan Blake Aquarium for transgenic fluorescent fish
US6929095B2 (en) * 2003-10-02 2005-08-16 Carl H. Brygger Roll-up stablizer
GB0325284D0 (en) * 2003-10-29 2003-12-03 Forinnova As Methods of identifying active genes
WO2005098428A2 (en) * 2004-04-07 2005-10-20 Marinus Pharmaceuticals, Inc. Method and system for screening compounds for muscular and/or neurological activity in animals
WO2006081539A2 (en) * 2005-01-27 2006-08-03 Zygogen, Llc Zebrafish models for alzheimer's disease
WO2007071062A1 (en) * 2005-12-22 2007-06-28 Krause Henry M Methods and compositions for the detection and isolation of ligands
US7663019B2 (en) * 2006-05-24 2010-02-16 North Carolina State University Transgenic snakes and methods of making
US8727554B2 (en) 2007-06-25 2014-05-20 Yorktown Technologies, L.P. Aquarium with adjustable lighting
US20090006219A1 (en) * 2007-06-29 2009-01-01 Alan Blake Method for distribution of an aquarium kit
US9968077B2 (en) 2014-11-07 2018-05-15 Glofish Llc Blue transgenic fluorescent ornamental fish
US20200113159A1 (en) * 2017-03-30 2020-04-16 GloFish, LLC Transgenic rainbow shark
WO2019165128A1 (en) * 2018-02-21 2019-08-29 Nemametrix Inc. Transgenic animal phenotyping platform and uses thereof
EP3782465B1 (de) 2019-08-23 2023-08-30 Universität Potsdam Transgenes zebrafischmodell für schlaganfall
CN114568343B (zh) * 2022-03-11 2023-04-07 成都合拓创展生物科技有限公司 制备眼病模型的头具及其应用
CN114931128A (zh) * 2022-06-30 2022-08-23 上海海洋大学 hoxaa基因簇缺失斑马鱼突变体的制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69231947T2 (de) 1991-03-15 2002-05-29 Hsc Res Dev Lp Genherstellung zur produktion von transgenfisch
CA2126138C (en) 1994-06-17 2001-08-21 Robert H. Devlin Transgenic fish and vectors therefor
WO1996003034A1 (en) 1994-07-27 1996-02-08 Massachusetts Institute Of Technology Method for retroviral vector insertion in fish
EP0769021A2 (de) 1995-04-06 1997-04-23 Dalhousie University Transgene fische zur behandlung von diabetes
US6380458B1 (en) * 1997-06-09 2002-04-30 Medical College Of Georgia Research Institute, Inc. Cell-lineage specific expression in transgenic zebrafish

Also Published As

Publication number Publication date
ATE223483T1 (de) 2002-09-15
DK0986640T3 (da) 2003-01-06
US6380458B1 (en) 2002-04-30
AU7955898A (en) 1998-12-30
ES2179512T3 (es) 2003-01-16
PT986640E (pt) 2002-12-31
EP0986640B1 (de) 2002-09-04
JP2002504821A (ja) 2002-02-12
AU754993B2 (en) 2002-11-28
WO1998056902A2 (en) 1998-12-17
US20020178461A1 (en) 2002-11-28
EP1240824A1 (de) 2002-09-18
EP0986640A2 (de) 2000-03-22
DE69807687D1 (de) 2002-10-10
CA2293722A1 (en) 1998-12-17
US20100212038A1 (en) 2010-08-19
WO1998056902A3 (en) 1999-03-04

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee