DE69805860D1 - Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel - Google Patents

Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel

Info

Publication number
DE69805860D1
DE69805860D1 DE69805860T DE69805860T DE69805860D1 DE 69805860 D1 DE69805860 D1 DE 69805860D1 DE 69805860 T DE69805860 T DE 69805860T DE 69805860 T DE69805860 T DE 69805860T DE 69805860 D1 DE69805860 D1 DE 69805860D1
Authority
DE
Germany
Prior art keywords
paclitaxel
water
similar compounds
soluble
preliminary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69805860T
Other languages
English (en)
Other versions
DE69805860T2 (de
Inventor
Hermanus Wiegerinck
Duncan Sperling
Lesly Braamer
Wilhelmus Damen
Wilhelm Scheeren
Vos Dick De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmachemie BV
Original Assignee
Pharmachemie BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachemie BV filed Critical Pharmachemie BV
Application granted granted Critical
Publication of DE69805860D1 publication Critical patent/DE69805860D1/de
Publication of DE69805860T2 publication Critical patent/DE69805860T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DE69805860T 1998-08-21 1998-08-21 Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel Expired - Fee Related DE69805860T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL1998/000473 WO2000010988A1 (en) 1998-08-21 1998-08-21 Water soluble analogs and prodrugs of paclitaxel

Publications (2)

Publication Number Publication Date
DE69805860D1 true DE69805860D1 (de) 2002-07-11
DE69805860T2 DE69805860T2 (de) 2003-01-02

Family

ID=19866454

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69805860T Expired - Fee Related DE69805860T2 (de) 1998-08-21 1998-08-21 Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel

Country Status (11)

Country Link
US (1) US6344571B2 (de)
EP (1) EP1105379B1 (de)
JP (1) JP2002523407A (de)
AT (1) ATE218560T1 (de)
AU (1) AU8889998A (de)
CA (1) CA2341234A1 (de)
DE (1) DE69805860T2 (de)
DK (1) DK1105379T3 (de)
ES (1) ES2179526T3 (de)
PT (1) PT1105379E (de)
WO (1) WO2000010988A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6414015B1 (en) 2000-01-28 2002-07-02 Utah State University Laulimalide microtubule stabilizing agents
AU7007001A (en) 2000-06-22 2002-01-02 Nitromed Inc Nitrosated and nitrosylated taxanes, compositions and methods of use
US7239636B2 (en) 2001-07-23 2007-07-03 Broadcom Corporation Multiple virtual channels for use in network devices
ITPD20020271A1 (it) 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
US20050148534A1 (en) * 2003-09-22 2005-07-07 Castellino Angelo J. Small molecule compositions and methods for increasing drug efficiency using compositions thereof
BRPI0608173A2 (pt) * 2005-02-24 2010-11-09 Elan Pharma Int Ltd composição, uso da mesma, e, método de produzir uma composição de docetaxel nanoparticulada ou análogo do mesmo
TW200731991A (en) * 2005-12-20 2007-09-01 Sonus Pharma Inc Lipophilic di(anticancer drug) compounds, compositions and related methods
CN101029034B (zh) * 2007-03-30 2010-05-26 浙江大学 多烯紫杉醇水溶性衍生物及制备方法和用途
CN106800542A (zh) * 2016-12-31 2017-06-06 辰欣药业股份有限公司 一种亲水性紫杉醇类化合物及其制备方法
CN108424405A (zh) * 2018-03-06 2018-08-21 华东师范大学 伏立诺他和紫杉醇的共前药及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
WO1994005282A1 (en) * 1992-09-04 1994-03-17 The Scripps Research Institute Water soluble taxol derivatives

Also Published As

Publication number Publication date
WO2000010988A8 (en) 2000-06-15
DE69805860T2 (de) 2003-01-02
EP1105379B1 (de) 2002-06-05
JP2002523407A (ja) 2002-07-30
AU8889998A (en) 2000-03-14
US20010018531A1 (en) 2001-08-30
ATE218560T1 (de) 2002-06-15
DK1105379T3 (da) 2002-08-19
CA2341234A1 (en) 2000-03-02
ES2179526T3 (es) 2003-01-16
EP1105379A1 (de) 2001-06-13
PT1105379E (pt) 2002-10-31
WO2000010988A1 (en) 2000-03-02
US6344571B2 (en) 2002-02-05

Similar Documents

Publication Publication Date Title
EA199900937A1 (ru) Фармацевтические композиции, содержащие вориконазол
DZ3312A1 (de) Azetidinderivate enthaltende pharmazeutische zusammensetzungen, die azetidinderivate und deren herstellung
CY1106522T1 (el) Ετepοκυκλικη ενωση και αντικαρκινικο μεσο που πepιεχει την ιδια ως δραστικο συστατικο
GB2363985B (en) Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
BR0207640A (pt) Composição farmacêutica oral de cefpodoxima proxetil
NO954072D0 (no) Vannopplöselige camptotecinderivater, fremgangsmåte for deres fremstilling og deres anvendelse som antitumormidler
PA8495101A1 (es) Derivados de 13-metileritromicina
ES2243579T3 (es) Derivados de pirazolopirideno.
PL1682528T3 (pl) Pochodne benzo[b][1,4]dioksepiny
HUP0003571A2 (hu) 6,9-Hídkötésű eritromicin-származékok
DE69805860D1 (de) Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel
MD1560F2 (en) Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
EA200000431A2 (ru) Новые замещенные димерные соединения, способ их получения и фармацевтические композиции, содержащие их
EP1326596A4 (de) Pharmazeutische zusammensetzungen die ein dibenzocyclooctanlignanderivat enthalten zur vorbeugung und behandlung neurodegenerativer erkrankungen
EA200201024A1 (ru) Фармацевтические композиции, содержащие олигосахариды, и их получение
SE9403137D0 (sv) Derivatives of carbohydrates and compositions containing them
HUP0302880A2 (hu) Egy ciklusos depszipeptid javított aktivitással rendelkező kristályos formáját tartalmazó gyógyászati készítmények
EP1411956B8 (de) Verwendung von übersulfatierten polysacchariden als hiv-hemmer
EA200000261A3 (ru) Новые замещенные димерные соединения, способ их получения и содержащияся их фармацевтическая композиция
BR0213463A (pt) Composições farmacêuticas contendo macrólidos
ATE301997T1 (de) Antivirale therapie
WO2002083641A3 (en) Amino-aza-cyclohexanes for the treatment of malaria
DE69632352D1 (de) Inositolderivate und diese enthaltende pharmazeutische zusammensetzungen
BR9915898A (pt) Compostos, composição farmacêutica, e, utilização de um composto
DE60104288D1 (de) Antivirale therapie

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee