DE69802858T2 - Kondensierte Piperin-Derivate als Stickstoffmonoxid-Synthese-Hemmer - Google Patents

Kondensierte Piperin-Derivate als Stickstoffmonoxid-Synthese-Hemmer

Info

Publication number
DE69802858T2
DE69802858T2 DE69802858T DE69802858T DE69802858T2 DE 69802858 T2 DE69802858 T2 DE 69802858T2 DE 69802858 T DE69802858 T DE 69802858T DE 69802858 T DE69802858 T DE 69802858T DE 69802858 T2 DE69802858 T2 DE 69802858T2
Authority
DE
Germany
Prior art keywords
condensed
nitric oxide
synthesis inhibitors
oxide synthesis
piperine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69802858T
Other languages
English (en)
Other versions
DE69802858D1 (de
Inventor
Naoyuki Taniguchi
Kaoru Kobayashi
Masao Naka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of DE69802858D1 publication Critical patent/DE69802858D1/de
Application granted granted Critical
Publication of DE69802858T2 publication Critical patent/DE69802858T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69802858T 1997-04-10 1998-04-09 Kondensierte Piperin-Derivate als Stickstoffmonoxid-Synthese-Hemmer Expired - Fee Related DE69802858T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9183097 1997-04-10
JP27319697 1997-10-07

Publications (2)

Publication Number Publication Date
DE69802858D1 DE69802858D1 (de) 2002-01-24
DE69802858T2 true DE69802858T2 (de) 2002-08-08

Family

ID=26433266

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802858T Expired - Fee Related DE69802858T2 (de) 1997-04-10 1998-04-09 Kondensierte Piperin-Derivate als Stickstoffmonoxid-Synthese-Hemmer

Country Status (14)

Country Link
US (2) US6110930A (de)
EP (1) EP0870763B1 (de)
KR (1) KR19980081287A (de)
CN (1) CN1202486A (de)
AT (1) ATE210647T1 (de)
AU (1) AU746048B2 (de)
CA (1) CA2234571A1 (de)
DE (1) DE69802858T2 (de)
DK (1) DK0870763T3 (de)
ES (1) ES2169886T3 (de)
HU (1) HUP9800865A3 (de)
NO (1) NO310618B1 (de)
PT (1) PT870763E (de)
TW (1) TW427979B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2793248B1 (fr) * 1999-05-03 2001-06-29 Adir Nouveaux derives de 2,3-methano-aminoacides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU5246000A (en) * 1999-06-09 2000-12-28 Ono Pharmaceutical Co. Ltd. Analgesics
FR2794647A1 (fr) * 1999-06-11 2000-12-15 Centre Nat Rech Scient Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules
BR0011780A (pt) * 1999-06-22 2002-05-21 Ono Pharmaceutical Co Processo para a preparação de compostos intermediários de drogas
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2001232259A1 (en) * 2000-02-10 2001-08-20 Ono Pharmaceutical Co., Ltd. Remedies for sjoegren's syndrome
AU2001296028A1 (en) * 2000-10-30 2002-05-15 Ono Pharmaceutical Co. Ltd. Remedies for extraocular inflammatory diseases
US20040235890A1 (en) * 2001-09-10 2004-11-25 Masaharu Komeno Remedies for allergic diseases
JP2006096665A (ja) * 2002-10-29 2006-04-13 Ono Pharmaceut Co Ltd 脊柱管狭窄症治療剤
WO2004101523A1 (en) * 2003-05-17 2004-11-25 Korea Research Institute Of Bioscience And Biotechnology Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
US20090186929A1 (en) * 2003-11-10 2009-07-23 U.S. Department Of Veterans Affairs Method and agent for inducing apoptosis/cell death in leukemia cells
US20050234026A1 (en) * 2003-11-10 2005-10-20 Weinberg Joe B Method and agent for inducing apoptosis/cell death in leukemia cells
US7364437B2 (en) * 2005-08-04 2008-04-29 Seagate Technology Llc Electronic device housing
WO2008101602A2 (en) 2007-02-19 2008-08-28 Dsm Ip Assets B.V. Catalysts containing platinum group metal nanoparticles and process for production of dispersions of nanoparticles of platinum group metal
WO2018035046A1 (en) 2016-08-15 2018-02-22 President And Fellows Of Harvard College Treating infections using idsd from proteus mirabilis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504028A (ja) * 1993-10-21 1997-04-22 ジー．ディー．サール アンド カンパニー 酸化窒素シンターゼ抑制剤として有用なアミジノ誘導体
WO1996014842A1 (en) * 1994-11-15 1996-05-23 Merck & Co., Inc. Substituted heterocycles as inhibitors of nitric oxide synthase
US5629322A (en) * 1994-11-15 1997-05-13 Merck & Co., Inc. Cyclic amidine analogs as inhibitors of nitric oxide synthase
CN1190390A (zh) * 1995-05-10 1998-08-12 G.D.瑟尔公司 由环状脒衍生的氧化氮合成酶抑制剂

Also Published As

Publication number Publication date
NO981658L (no) 1998-10-12
ATE210647T1 (de) 2001-12-15
CN1202486A (zh) 1998-12-23
TW427979B (en) 2001-04-01
DE69802858D1 (de) 2002-01-24
HUP9800865A2 (hu) 1999-01-28
ES2169886T3 (es) 2002-07-16
CA2234571A1 (en) 1998-10-10
NO981658D0 (no) 1998-04-08
EP0870763B1 (de) 2001-12-12
HUP9800865A3 (en) 1999-03-01
AU6077798A (en) 1998-10-15
PT870763E (pt) 2002-06-28
KR19980081287A (ko) 1998-11-25
NO310618B1 (no) 2001-07-30
US6110930A (en) 2000-08-29
EP0870763A1 (de) 1998-10-14
HU9800865D0 (en) 1998-05-28
US6228866B1 (en) 2001-05-08
AU746048B2 (en) 2002-04-11
DK0870763T3 (da) 2002-03-11

Similar Documents

Publication Publication Date Title
DE69802858D1 (de) Kondensierte Piperin-Derivate als Stickstoffmonoxid-Synthese-Hemmer
NO961403D0 (no) Amidinoderivater for anvendelse som nitrogenmonoksyd-syntaseinhibitor
WO2002100860A3 (fr) Composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
IL148313A0 (en) N-heterocyclic derivatives as nos inhibitors
NO993996D0 (no) N-heterosykliske derivater som NOS-inhibitorer
ES2182234T3 (es) Inhibidores de metaloproteasa.
TR200302268T4 (tr) NOS inhibitörleri olarak yararlı N-heterosiklik türevler.
NO20004531L (no) Halogenerte amidinoaminosyre-derivater anvendbare som nitrogenoksid syntase inhibitorer
ATE353216T1 (de) 1-substituierten imidazol derivaten als nos inhibitoren
WO2000005214A3 (en) Isoquinolines as urokinase inhibitors
MXPA04009421A (es) Compuestos de tiazol-2-ilimina como inhibidores de la pde-7.
DK1054869T3 (da) 3,4-Dihydroquinolin-derivater som inhibitorer for nitrogenmonoxid-synthase (NOS)
DE50311388D1 (de) Nicht-peptidische brs-3-agonisten
EP1118615A4 (de) Salze von pyridopyrazinderivaten und kristalle davon
MXPA04003478A (es) Sintesis de (4-bromofenil)(4-piperidil)metanona-(z)-o-etiloxima y sales.
ES2184633A1 (es) Procedimiento para la preparacion de derivados de 4-(imidazol-1-il) bencenosulfonamida.
DK1098901T3 (da) Nye 6-deoxyerythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler
MXPA05011840A (es) Procedimiento para cristalizar sales de guanidinio.
TH64772A (th) อนุพันธ์ของกรดฮาโลจีเนต 2-อะมิโน-4,5 เฮพทีในอิกที่ใช้เป็นตัวยับยั้งไนตริกออกไซด์ซินเทส
EP1795192A3 (de) 1-(pyridazin-3-yl)-Imidazol Derivaten als NO-Synthase (NOS) Hemmer

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee