DE69800486T2 - Immunoassay für Glucuronid-Metabolite von LSD - Google Patents

Immunoassay für Glucuronid-Metabolite von LSD

Info

Publication number
DE69800486T2
DE69800486T2 DE69800486T DE69800486T DE69800486T2 DE 69800486 T2 DE69800486 T2 DE 69800486T2 DE 69800486 T DE69800486 T DE 69800486T DE 69800486 T DE69800486 T DE 69800486T DE 69800486 T2 DE69800486 T2 DE 69800486T2
Authority
DE
Germany
Prior art keywords
lsd
immunoassay
glucuronide metabolites
glucuronide
metabolites
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69800486T
Other languages
English (en)
Other versions
DE69800486D1 (de
Inventor
William A Coty
Jeffrey E Shindelman
Paul R Morrill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microgenics Corp
Original Assignee
Microgenics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microgenics Corp filed Critical Microgenics Corp
Publication of DE69800486D1 publication Critical patent/DE69800486D1/de
Application granted granted Critical
Publication of DE69800486T2 publication Critical patent/DE69800486T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G01N33/942—Serotonin, i.e. 5-hydroxy-tryptamine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
DE69800486T 1997-05-21 1998-05-20 Immunoassay für Glucuronid-Metabolite von LSD Expired - Lifetime DE69800486T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4725697P 1997-05-21 1997-05-21
US09/026,780 US6207396B1 (en) 1995-11-20 1998-02-20 Immunoassay reagents and methods for determination of LSD and LSD metabolites

Publications (2)

Publication Number Publication Date
DE69800486D1 DE69800486D1 (de) 2001-02-22
DE69800486T2 true DE69800486T2 (de) 2001-05-03

Family

ID=26701649

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69800486T Expired - Lifetime DE69800486T2 (de) 1997-05-21 1998-05-20 Immunoassay für Glucuronid-Metabolite von LSD

Country Status (3)

Country Link
US (1) US6207396B1 (de)
EP (1) EP0880029B1 (de)
DE (1) DE69800486T2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2775299A (en) * 1998-02-20 1999-09-06 Microgenics Corporation Immunoassays for determination of lsd and lsd metabolites
US6548645B1 (en) * 1999-06-18 2003-04-15 Microgenetics Corporation Immunoassay for 2-oxo-3-hydroxy LSD
US6794496B2 (en) 2000-04-07 2004-09-21 Roche Diagnostics Corporation Immunoassay for LSD and 2-oxo-3-hydroxy-LSD
ES2361907T3 (es) 2001-12-20 2011-06-24 Randox Laboratories Ltd. Haptenos, inmunógenos, anticuerpos y conjugados para lsd 2-oxo-3-hidroxi.
EP1321772B1 (de) * 2001-12-20 2008-09-17 Randox Laboratories Ltd. Verfahren und Kit zum Nachweis oder zur Bestimmung von 3,4-Methylendioxymethamphetamin
US20060223998A1 (en) * 2005-03-30 2006-10-05 Fang-Jie Zhang Synthetic LSD metabolite for preparing haptens used in an LSD metabolite immunoassay
US10643167B2 (en) 2016-07-28 2020-05-05 Honeywell International Inc. MPC with unconstrained dependent variables for KPI performance analysis
EP4153564A4 (de) 2020-05-19 2024-06-19 Cybin IRL Limited Deuterierte tryptaminderivate und verfahren zur verwendung
CN116391128A (zh) * 2020-10-24 2023-07-04 巴塞尔大学医院 人血浆中麦角酸二乙基酰胺（lsd）和2,3-二氢-3-羟基-2-氧代麦角二乙胺（o-h-lsd）的定量方法
CN114317449B (zh) * 2021-12-28 2023-08-15 无锡迪腾敏生物科技有限公司 麦角乙二胺抗原、麦角乙二胺单克隆抗体、杂交瘤细胞株及应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3249617A (en) 1966-05-03 Alkylated d-lyserglc acid
CH344731A (de) 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
CH396024A (de) 1960-08-22 1965-07-31 Sandoz Ag Verfahren zur Herstellung von neuen Hydrierungsprodukten der Lysergsäure-Reihe
US3249619A (en) 1964-07-24 1966-05-03 Dow Chemical Co Carbamate esters of trichloro and tetrachloro pyridine
US4375414A (en) 1971-05-20 1983-03-01 Meir Strahilevitz Immunological methods for removing species from the blood circulatory system and devices therefor
US4208479A (en) 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
US4233401A (en) 1977-07-14 1980-11-11 Syva Company Antienzyme homogeneous competitive binding assay
US4236893A (en) 1979-04-09 1980-12-02 Minnesota Mining And Manufacturing Company Method for the assay of classes of antigen-specific antibodies
US4708929A (en) 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
DE3919915A1 (de) 1989-06-19 1990-12-20 Boehringer Mannheim Gmbh Aminoalkylmaleimide und davon abgeleitete hapten- und antigenderivate sowie konjugate mit peptiden oder proteinen
IT1232350B (it) 1989-08-04 1992-01-28 Poli Ind Chimica Spa Nuovi ergolinici derivati dalla prolina e strutture correlate con attivita' dopaminergica.
BR9405664A (pt) 1993-01-21 1996-04-30 Univ Georgia Composto imunogenio processos para evitar a toxicose por festuca em um herbivoro para tratar a toxicose por festuca em um herbivoro anticorpo purificado lingagem de célula de hidridoma e anticorpo
FR2725023B1 (fr) 1994-09-28 1997-01-31 Gks Technologies Diagnostic direct d'haptenes
US5843682A (en) * 1995-11-20 1998-12-01 Boehringer Mannheim Corporation N-1-carboxyalkyl derivatives of LSD
US6063908A (en) 1996-07-02 2000-05-16 Roche Diagnostics Corporation Reagents for lysergic acid diethylamide immunoassay

Also Published As

Publication number Publication date
DE69800486D1 (de) 2001-02-22
EP0880029B1 (de) 2001-01-17
EP0880029A1 (de) 1998-11-25
US6207396B1 (en) 2001-03-27

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