DE69738803D1 - Apoptosis induzierendes protein und dieses kodierendes gen - Google Patents

Apoptosis induzierendes protein und dieses kodierendes gen

Info

Publication number
DE69738803D1
DE69738803D1 DE69738803T DE69738803T DE69738803D1 DE 69738803 D1 DE69738803 D1 DE 69738803D1 DE 69738803 T DE69738803 T DE 69738803T DE 69738803 T DE69738803 T DE 69738803T DE 69738803 D1 DE69738803 D1 DE 69738803D1
Authority
DE
Germany
Prior art keywords
apoptosis inducing
inducing protein
encoding gene
kinase activity
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738803T
Other languages
English (en)
Inventor
Kohei Miyazono
Hidenori Ichijo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japanese Foundation for Cancer Research
Original Assignee
Japanese Foundation for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26459470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69738803(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japanese Foundation for Cancer Research filed Critical Japanese Foundation for Cancer Research
Application granted granted Critical
Publication of DE69738803D1 publication Critical patent/DE69738803D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69738803T 1996-04-19 1997-04-18 Apoptosis induzierendes protein und dieses kodierendes gen Expired - Lifetime DE69738803D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12232096 1996-04-19
JP24106396A JP3839103B2 (ja) 1996-04-19 1996-08-23 アポトーシス誘導タンパク質およびそれをコードする遺伝子
PCT/JP1997/001348 WO1997040143A1 (fr) 1996-04-19 1997-04-18 Proteine inductrice de l'apoptose et gene codant pour elle

Publications (1)

Publication Number Publication Date
DE69738803D1 true DE69738803D1 (de) 2008-08-14

Family

ID=26459470

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738803T Expired - Lifetime DE69738803D1 (de) 1996-04-19 1997-04-18 Apoptosis induzierendes protein und dieses kodierendes gen

Country Status (7)

Country Link
US (1) US6194187B1 (de)
EP (1) EP0896055B1 (de)
JP (1) JP3839103B2 (de)
AT (1) ATE399866T1 (de)
AU (1) AU2576397A (de)
DE (1) DE69738803D1 (de)
WO (1) WO1997040143A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999040912A1 (en) * 1998-02-11 1999-08-19 The Brigham And Women's Hospital, Inc. Method of stimulating apoptosis using trichothecene mycotoxins
US6080546A (en) * 1999-07-23 2000-06-27 Isis Pharmaceuticals Inc. Antisense modulation of MEKK5 expression
US20030224378A1 (en) * 2001-04-10 2003-12-04 Plowman Gregory D. Novel human protein kinases and protein kinase-like enzymes
AU2002224022A1 (en) * 2000-11-10 2002-05-21 Kissei Pharmaceutical Co. Ltd. Preventives or remedies for endoplasmic reticulum stress-associated diseases
WO2003063905A1 (fr) * 2002-01-31 2003-08-07 Center For Advanced Science And Technology Incubation, Ltd. Medicaments preventifs ou remedes pour maladies immunologiques
WO2004026407A1 (en) * 2002-09-06 2004-04-01 Institut Curie Use of inhibitors of compounds involved in the jun kinase (jnk) biochemical cellular pathway for the treatment or diagnosis of liposarcomas
EP1582586A4 (de) * 2002-11-22 2007-03-14 Takeda Pharmaceutical Mit apoptose assoziiertes protein und dessen verwendung
JP4488720B2 (ja) * 2002-11-22 2010-06-23 武田薬品工業株式会社 アポトーシス関連蛋白質およびその用途
US20070167386A1 (en) * 2003-07-28 2007-07-19 Osaka Industrial Promotion Organization Remedy for cardiac failure containing ask1 inhibitor as active ingredient and method for screening the same
EP1743945A4 (de) * 2004-04-27 2009-06-10 Takeda Pharmaceutical Screening-verfahren
WO2005114199A1 (en) * 2004-05-13 2005-12-01 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with mitogen-activated protein kinase kinase kinase 5 (map3k5)
WO2009030094A1 (fr) * 2007-09-06 2009-03-12 Zhejiang University Fonction et utilisation d'une nouvelle protéine induisant une apoptose associée aux lysosomes contenant les domaines ph et fyve (lapf)
WO2011041293A1 (en) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
PT2531501E (pt) 2010-02-03 2014-02-17 Takeda Pharmaceutical Inibidores da cinase de regulação do sinal de apoptose 1
WO2020006429A1 (en) 2018-06-28 2020-01-02 Hepatikos Therapeutics, Llc Ask1 isoindolin-1-one inhibitors and methods of use thereof

Also Published As

Publication number Publication date
EP0896055A2 (de) 1999-02-10
JPH1093A (ja) 1998-01-06
AU2576397A (en) 1997-11-12
WO1997040143A1 (fr) 1997-10-30
ATE399866T1 (de) 2008-07-15
EP0896055B1 (de) 2008-07-02
US6194187B1 (en) 2001-02-27
JP3839103B2 (ja) 2006-11-01
EP0896055A4 (de) 2004-05-12

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