DE69737724D1 - Genidentifikationsverfahren - Google Patents

Genidentifikationsverfahren

Info

Publication number
DE69737724D1
DE69737724D1 DE69737724T DE69737724T DE69737724D1 DE 69737724 D1 DE69737724 D1 DE 69737724D1 DE 69737724 T DE69737724 T DE 69737724T DE 69737724 T DE69737724 T DE 69737724T DE 69737724 D1 DE69737724 D1 DE 69737724D1
Authority
DE
Germany
Prior art keywords
gene
interest
cells
pct
phenotype
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69737724T
Other languages
English (en)
Other versions
DE69737724T2 (de
Inventor
Louis Paul Deiss
Fruma Yehiely
Elena Efimova
Nora Cecilia Vasquez-Iaslop
Paz Einat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
QBI Enterprises Ltd
Original Assignee
QBI Enterprises Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by QBI Enterprises Ltd filed Critical QBI Enterprises Ltd
Application granted granted Critical
Publication of DE69737724D1 publication Critical patent/DE69737724D1/de
Publication of DE69737724T2 publication Critical patent/DE69737724T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69737724T 1996-11-13 1997-11-12 Genidentifikationsverfahren Expired - Fee Related DE69737724T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3054996P 1996-11-13 1996-11-13
US30549P 1996-11-13
PCT/US1997/020989 WO1998021366A1 (en) 1996-11-13 1997-11-12 Gene identification method

Publications (2)

Publication Number Publication Date
DE69737724D1 true DE69737724D1 (de) 2007-06-21
DE69737724T2 DE69737724T2 (de) 2008-06-12

Family

ID=21854744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737724T Expired - Fee Related DE69737724T2 (de) 1996-11-13 1997-11-12 Genidentifikationsverfahren

Country Status (9)

Country Link
US (1) US6057111A (de)
EP (1) EP0960212B1 (de)
JP (1) JP2001504694A (de)
AT (1) ATE361990T1 (de)
AU (1) AU5442198A (de)
CA (1) CA2269658A1 (de)
DE (1) DE69737724T2 (de)
IL (2) IL129507A0 (de)
WO (1) WO1998021366A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1034308A4 (de) * 1997-12-04 2002-04-03 Smithkline Beecham Corp Verfahren zur herstellung conditionell exprimierten mutanten zellen mit hilfe von expriemirten antisense sequenzen
US7816403B2 (en) * 1998-09-08 2010-10-19 University Of Utah Research Foundation Method of inhibiting ATF/CREB and cancer cell growth and pharmaceutical compositions for same
WO2000017335A1 (fr) * 1998-09-17 2000-03-30 Helix Research Institute BANQUES D'ADNc IMMOBILISES
EP1178052A3 (de) * 1999-01-27 2003-04-02 Elitra Pharmaceuticals, Inc. Gene identifiziert als notwendig für proliferation in Escherichia coli
US6720139B1 (en) 1999-01-27 2004-04-13 Elitra Pharmaceuticals, Inc. Genes identified as required for proliferation in Escherichia coli
JP2002535007A (ja) * 1999-01-27 2002-10-22 エリトラ ファーマシューティカルズ，インコーポレイテッド Ｅｓｃｈｅｒｉｃｈｉａｃｏｌｉの増殖に必要であると同定された遺伝子
JP2002537835A (ja) * 1999-03-12 2002-11-12 ジーピーシー バイオテク インコーポレイテッド 合成遺伝子エレメントを同定する方法及び試薬
AUPQ005299A0 (en) * 1999-04-29 1999-05-27 Commonwealth Scientific And Industrial Research Organisation Novel genes encoding wheat starch synthases and uses therefor
US6861220B2 (en) * 1999-09-08 2005-03-01 Ramot University Authority For Applied Research & Industrial Development Ltd Genetic screening methods
US6569623B1 (en) * 1999-09-08 2003-05-27 Ramot University Authority For Applied Research & Industrial Development Ltd. Genetic screening methods
US20040018529A1 (en) * 1999-10-20 2004-01-29 Yonghong Li Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage
WO2001034810A2 (en) * 1999-11-09 2001-05-17 Elitra Pharmaceuticals, Inc. Genes essential for microbial proliferation
KR20030003221A (ko) * 1999-12-23 2003-01-09 엘리트라 파마슈티컬즈, 인코포레이티드 대장균 증식에 필요한 유전자
US6783985B1 (en) 2000-02-18 2004-08-31 Elitra Pharmaceuticals Inc. Gene disruption methodologies for drug target discovery
JP2001245671A (ja) * 2000-03-07 2001-09-11 Chiba Prefecture ヒト神経芽細胞腫においてクローニングされた新規遺伝子及び新規遺伝子の断片
WO2001066733A1 (fr) 2000-03-07 2001-09-13 Chiba-Prefecture Sequences d'acides nucleiques presentant une expression accrue dans le neuroblastome benin par rapport au neuroblastome humain acritique
US20020133495A1 (en) * 2000-03-16 2002-09-19 Rienhoff Hugh Y. Database system and method
CA2404260A1 (en) * 2000-03-21 2001-09-27 Elitra Pharmaceuticals, Inc. Identification of essential genes in prokaryotes
US20040047852A1 (en) * 2001-03-02 2004-03-11 Kennedy Thomas Preston Method of treating cancer
US20020049772A1 (en) * 2000-05-26 2002-04-25 Hugh Rienhoff Computer program product for genetically characterizing an individual for evaluation using genetic and phenotypic variation over a wide area network
US20020010552A1 (en) * 2000-05-26 2002-01-24 Hugh Rienhoff System for genetically characterizing an individual for evaluation using genetic and phenotypic variation over a wide area network
US6713257B2 (en) 2000-08-25 2004-03-30 Rosetta Inpharmatics Llc Gene discovery using microarrays
IL159094A0 (en) * 2001-05-30 2004-05-12 Quark Biotech Inc Gene and polypeptide which opposes the fas pathway
US20030027223A1 (en) * 2001-06-29 2003-02-06 Muraca Patrick J. Specimen-linked G protein coupled receptor database
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US6808075B2 (en) * 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US7157274B2 (en) * 2002-06-24 2007-01-02 Cytonome, Inc. Method and apparatus for sorting particles
US20070065808A1 (en) * 2002-04-17 2007-03-22 Cytonome, Inc. Method and apparatus for sorting particles
FR2853911B1 (fr) * 2003-04-17 2005-07-08 Merck Sante Sas Gene induit par l'insuline, comme cible therapeutique dans le diabete
US20050053971A1 (en) * 2003-09-08 2005-03-10 Alex Chenchik Methods and constructs for developing cell lines for biological assays
US20070202505A1 (en) * 2003-09-08 2007-08-30 Alex Chenchik Methods for gene function analysis
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
US20110071047A1 (en) * 2007-10-27 2011-03-24 O.D. 260 Inc. Promoter detection and analysis
US20090111099A1 (en) * 2007-10-27 2009-04-30 Yongsheng Ma Promoter Detection and Analysis
JP5301652B2 (ja) 2008-07-25 2013-09-25 インフォコム株式会社 新規がん遺伝子ｎｒｆ２
SG11202007652UA (en) 2018-02-21 2020-09-29 Bristol Myers Squibb Co Camk2d antisense oligonucleotides and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05507203A (ja) * 1990-06-18 1993-10-21 アメリカ合衆国 真核性発現ベクター系

Also Published As

Publication number Publication date
IL129507A (en) 2009-08-03
CA2269658A1 (en) 1998-05-22
EP0960212A1 (de) 1999-12-01
AU5442198A (en) 1998-06-03
ATE361990T1 (de) 2007-06-15
WO1998021366A1 (en) 1998-05-22
IL129507A0 (en) 2000-02-29
US6057111A (en) 2000-05-02
EP0960212B1 (de) 2007-05-09
EP0960212A4 (de) 2004-05-06
JP2001504694A (ja) 2001-04-10
DE69737724T2 (de) 2008-06-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee