ATE361990T1 - Genidentifikationsverfahren - Google Patents

Genidentifikationsverfahren

Info

Publication number
ATE361990T1
ATE361990T1 AT97948335T AT97948335T ATE361990T1 AT E361990 T1 ATE361990 T1 AT E361990T1 AT 97948335 T AT97948335 T AT 97948335T AT 97948335 T AT97948335 T AT 97948335T AT E361990 T1 ATE361990 T1 AT E361990T1
Authority
AT
Austria
Prior art keywords
gene
interest
cells
pct
phenotype
Prior art date
Application number
AT97948335T
Other languages
English (en)
Inventor
Louis Deiss
Fruma Yehiely
Elena Efimova
Nora Cecilia Vasquez-Iaslop
Paz Einat
Original Assignee
Qbi Entpr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qbi Entpr Ltd filed Critical Qbi Entpr Ltd
Application granted granted Critical
Publication of ATE361990T1 publication Critical patent/ATE361990T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97948335T 1996-11-13 1997-11-12 Genidentifikationsverfahren ATE361990T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3054996P 1996-11-13 1996-11-13

Publications (1)

Publication Number Publication Date
ATE361990T1 true ATE361990T1 (de) 2007-06-15

Family

ID=21854744

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97948335T ATE361990T1 (de) 1996-11-13 1997-11-12 Genidentifikationsverfahren

Country Status (9)

Country Link
US (1) US6057111A (de)
EP (1) EP0960212B1 (de)
JP (1) JP2001504694A (de)
AT (1) ATE361990T1 (de)
AU (1) AU5442198A (de)
CA (1) CA2269658A1 (de)
DE (1) DE69737724T2 (de)
IL (2) IL129507A0 (de)
WO (1) WO1998021366A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1034308A4 (de) * 1997-12-04 2002-04-03 Smithkline Beecham Corp Verfahren zur herstellung conditionell exprimierten mutanten zellen mit hilfe von expriemirten antisense sequenzen
US7816403B2 (en) * 1998-09-08 2010-10-19 University Of Utah Research Foundation Method of inhibiting ATF/CREB and cancer cell growth and pharmaceutical compositions for same
AU5305499A (en) * 1998-09-17 2000-04-10 Helix Research Institute Immobilized cdna libraries
US6720139B1 (en) 1999-01-27 2004-04-13 Elitra Pharmaceuticals, Inc. Genes identified as required for proliferation in Escherichia coli
EP1178052A3 (de) * 1999-01-27 2003-04-02 Elitra Pharmaceuticals, Inc. Gene identifiziert als notwendig für proliferation in Escherichia coli
AU3584500A (en) * 1999-01-27 2000-08-18 Elitra Pharmaceuticals, Inc. Genes identified as required for proliferation in escherichia coli
CA2362414A1 (en) * 1999-03-12 2000-09-14 Gpc Biotech, Inc. Methods and reagents for identifying synthetic genetic elements
AUPQ005299A0 (en) * 1999-04-29 1999-05-27 Commonwealth Scientific And Industrial Research Organisation Novel genes encoding wheat starch synthases and uses therefor
US6861220B2 (en) * 1999-09-08 2005-03-01 Ramot University Authority For Applied Research & Industrial Development Ltd Genetic screening methods
US6569623B1 (en) * 1999-09-08 2003-05-27 Ramot University Authority For Applied Research & Industrial Development Ltd. Genetic screening methods
US20040018529A1 (en) * 1999-10-20 2004-01-29 Yonghong Li Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage
WO2001034810A2 (en) * 1999-11-09 2001-05-17 Elitra Pharmaceuticals, Inc. Genes essential for microbial proliferation
CA2395335A1 (en) * 1999-12-23 2001-07-05 Elitra Pharmaceuticals, Inc. Genes identified as required for proliferation of e. coli
US6783985B1 (en) 2000-02-18 2004-08-31 Elitra Pharmaceuticals Inc. Gene disruption methodologies for drug target discovery
US7087383B2 (en) 2000-03-07 2006-08-08 Hisamitsu Pharmaceutical Co., Inc. Nucleic acid sequences showing enhanced expression in benign neuroblastoma compared with acritical human neuroblastoma
JP2001245671A (ja) * 2000-03-07 2001-09-11 Chiba Prefecture ヒト神経芽細胞腫においてクローニングされた新規遺伝子及び新規遺伝子の断片
US20020019746A1 (en) * 2000-03-16 2002-02-14 Rienhoff Hugh Y. Aggregating persons with a select profile for further medical characterization
US20020061569A1 (en) * 2000-03-21 2002-05-23 Robert Haselbeck Identification of essential genes in prokaryotes
US20040047852A1 (en) * 2001-03-02 2004-03-11 Kennedy Thomas Preston Method of treating cancer
US20020049772A1 (en) * 2000-05-26 2002-04-25 Hugh Rienhoff Computer program product for genetically characterizing an individual for evaluation using genetic and phenotypic variation over a wide area network
US20020010552A1 (en) * 2000-05-26 2002-01-24 Hugh Rienhoff System for genetically characterizing an individual for evaluation using genetic and phenotypic variation over a wide area network
US6713257B2 (en) 2000-08-25 2004-03-30 Rosetta Inpharmatics Llc Gene discovery using microarrays
US20020182694A1 (en) * 2001-05-30 2002-12-05 Paz Einat Novel gene and polypeptide which opposes the Fas pathway
WO2003002977A1 (en) * 2001-06-29 2003-01-09 Protea Biosciences, Inc. Specimen-linked g protein coupled receptor database
US6808075B2 (en) * 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US20070065808A1 (en) * 2002-04-17 2007-03-22 Cytonome, Inc. Method and apparatus for sorting particles
US7157274B2 (en) * 2002-06-24 2007-01-02 Cytonome, Inc. Method and apparatus for sorting particles
US6976590B2 (en) * 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
FR2853911B1 (fr) * 2003-04-17 2005-07-08 Merck Sante Sas Gene induit par l'insuline, comme cible therapeutique dans le diabete
US20050053971A1 (en) * 2003-09-08 2005-03-10 Alex Chenchik Methods and constructs for developing cell lines for biological assays
US20070202505A1 (en) * 2003-09-08 2007-08-30 Alex Chenchik Methods for gene function analysis
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
US20110071047A1 (en) * 2007-10-27 2011-03-24 O.D. 260 Inc. Promoter detection and analysis
US20090111099A1 (en) * 2007-10-27 2009-04-30 Yongsheng Ma Promoter Detection and Analysis
KR20110036610A (ko) 2008-07-25 2011-04-07 인포콤 가부시키가이샤 신규 온코진 ｎｒｆ2
EP3755800A1 (de) 2018-02-21 2020-12-30 Bristol-Myers Squibb Company Camk2d-antisense-oligonukleotide und verwendungen davon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU652566B2 (en) * 1990-06-18 1994-09-01 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Eukaryotic expression vector system

Also Published As

Publication number Publication date
WO1998021366A1 (en) 1998-05-22
AU5442198A (en) 1998-06-03
IL129507A (en) 2009-08-03
JP2001504694A (ja) 2001-04-10
DE69737724D1 (de) 2007-06-21
IL129507A0 (en) 2000-02-29
DE69737724T2 (de) 2008-06-12
CA2269658A1 (en) 1998-05-22
EP0960212B1 (de) 2007-05-09
US6057111A (en) 2000-05-02
EP0960212A4 (de) 2004-05-06
EP0960212A1 (de) 1999-12-01

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