DE69735100D1 - Methoden zur diagnose der klinischen subtypen von morbus crohn - Google Patents
Methoden zur diagnose der klinischen subtypen von morbus crohnInfo
- Publication number
- DE69735100D1 DE69735100D1 DE69735100T DE69735100T DE69735100D1 DE 69735100 D1 DE69735100 D1 DE 69735100D1 DE 69735100 T DE69735100 T DE 69735100T DE 69735100 T DE69735100 T DE 69735100T DE 69735100 D1 DE69735100 D1 DE 69735100D1
- Authority
- DE
- Germany
- Prior art keywords
- diagnosis
- methods
- morbus crohn
- clinical subtypes
- subtypes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63067296A | 1996-04-12 | 1996-04-12 | |
US630672 | 1996-04-12 | ||
US08/689,870 US5874233A (en) | 1996-04-12 | 1996-08-15 | Methods of diagnosing a clinical subtype of Crohn's disease with features of ulcerative colitis |
US689870 | 1996-08-15 | ||
PCT/US1997/006791 WO1997039356A1 (en) | 1996-04-12 | 1997-04-11 | Methods of diagnosing clinical subtypes of crohn's disease |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69735100D1 true DE69735100D1 (de) | 2006-04-06 |
DE69735100T2 DE69735100T2 (de) | 2006-08-31 |
Family
ID=27091207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69735100T Expired - Lifetime DE69735100T2 (de) | 1996-04-12 | 1997-04-11 | Methoden zur diagnose der klinischen subtypen von morbus crohn |
Country Status (7)
Country | Link |
---|---|
US (1) | US5874233A (de) |
EP (1) | EP0906573B1 (de) |
AU (1) | AU2991697A (de) |
CA (1) | CA2251567C (de) |
DE (1) | DE69735100T2 (de) |
IL (1) | IL126534A (de) |
WO (1) | WO1997039356A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6223317B1 (en) | 1998-02-28 | 2001-04-24 | Micron Technology, Inc. | Bit synchronizers and methods of synchronizing and calculating error |
US6218129B1 (en) * | 1998-05-15 | 2001-04-17 | Prometheus Laboratories, Inc. | Inflammatory bowel disease first step assay system |
US6869762B1 (en) | 1999-12-10 | 2005-03-22 | Whitehead Institute For Biomedical Research | Crohn's disease-related polymorphisms |
US7138237B1 (en) * | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
US6872540B2 (en) | 2001-10-26 | 2005-03-29 | Techlab, Inc. | Method and apparatus for distinguishing Crohn's disease from ulcerative colitis and other gastrointestinal diseases by detecting the presence of fecal antibodies to Saccharomyces cerevisiae |
US20040053263A1 (en) * | 2002-08-30 | 2004-03-18 | Abreu Maria T. | Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease |
ES2379066T3 (es) * | 2002-09-05 | 2012-04-20 | Techlab, Inc. | Método para distinguir la colitis ulcerosa de la enfermedad de Crohn detectando la presencia de anticuerpos citoplasmáticos antineutrófilos (ANCA) fecales |
US20040076960A1 (en) * | 2002-10-18 | 2004-04-22 | Taylor Kent D. | Methods of using a NOD2/CARD15 haplotype to diagnose Crohn's disease |
US7785818B2 (en) * | 2002-10-25 | 2010-08-31 | Techlab, Inc. | Inflammatory bowel disease and irritable bowel syndrome IBD-first chek diagnostic panel |
US7662569B2 (en) * | 2003-04-11 | 2010-02-16 | Cedars-Sinai Medical Center | Methods of assessing Crohn's disease patient phenotype by I2 serologic response |
FR2876798A1 (fr) | 2004-10-14 | 2006-04-21 | Univ Clermont Auvergne | Diagnostic et traitement de la maladie de crohn |
WO2008101133A2 (en) * | 2007-02-14 | 2008-08-21 | Cedars-Sinai Medical Center | Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease |
US20100021455A1 (en) * | 2004-12-08 | 2010-01-28 | Cedars-Sinai Medical Center | Methods for diagnosis and treatment of crohn's disease |
WO2008109782A2 (en) * | 2007-03-06 | 2008-09-12 | Cedars-Sinai Medical Center | Diagnosis of inflammatory bowel disease in children |
WO2008106451A2 (en) * | 2007-02-26 | 2008-09-04 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
WO2008116150A2 (en) | 2007-03-21 | 2008-09-25 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (ipaa) factors in the treatment of inflammatory bowel disease |
WO2008134569A2 (en) * | 2007-04-26 | 2008-11-06 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease in the puerto rican population |
US20100144903A1 (en) * | 2007-05-04 | 2010-06-10 | Cedars-Sinai Medical Center | Methods of diagnosis and treatment of crohn's disease |
US20110177969A1 (en) * | 2008-10-01 | 2011-07-21 | Cedars-Sinai Medical Center | The role of il17rd and the il23-1l17 pathway in crohn's disease |
US20110189685A1 (en) * | 2008-10-22 | 2011-08-04 | Cedars-Sinai Medical Center | Methods of using jak3 genetic variants to diagnose and predict crohn's disease |
WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
CA2801575A1 (en) * | 2010-06-04 | 2011-12-08 | Prometheus Laboratories Inc. | Methods for improving inflammatory bowel disease diagnosis |
US8445215B1 (en) | 2010-07-23 | 2013-05-21 | Nestec S.A. | Assays and methods for the detection of Crohn's disease |
CA2908553A1 (en) | 2013-03-27 | 2014-10-02 | Cedars-Sinai Medical Center | Mitigation and reversal of fibrosis and inflammation by inhibition of tl1a function and related signaling pathways |
WO2015010108A1 (en) | 2013-07-19 | 2015-01-22 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
KR20180127416A (ko) | 2016-03-17 | 2018-11-28 | 세다르스-신나이 메디칼 센터 | Rnaset2를 통한 염증성 장 질환의 진단 방법 |
US10626180B2 (en) | 2017-04-20 | 2020-04-21 | Cedars-Sinai Medical Center | Methods of treating and predicting non-response to anti-TNF treatment in subjects with inflammatory bowel disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE193601T1 (de) * | 1993-03-10 | 2000-06-15 | Cedars Sinai Medical Center | Verfahren zum selektiven nachweis von perinuklearen anti-neutrophilen cytoplasmischen antikörpern bei ulzerativen kolitis oder primärer sclerotischer cholangitis |
US5830675A (en) * | 1993-03-10 | 1998-11-03 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis |
US5681699A (en) * | 1994-02-11 | 1997-10-28 | Cedars-Sinai Medical Center | Methods of diagnosing ulcerative colitis and Crohn's disease |
-
1996
- 1996-08-15 US US08/689,870 patent/US5874233A/en not_active Expired - Lifetime
-
1997
- 1997-04-11 IL IL12653497A patent/IL126534A/xx not_active IP Right Cessation
- 1997-04-11 DE DE69735100T patent/DE69735100T2/de not_active Expired - Lifetime
- 1997-04-11 CA CA002251567A patent/CA2251567C/en not_active Expired - Lifetime
- 1997-04-11 EP EP97924512A patent/EP0906573B1/de not_active Expired - Lifetime
- 1997-04-11 WO PCT/US1997/006791 patent/WO1997039356A1/en active IP Right Grant
- 1997-04-11 AU AU29916/97A patent/AU2991697A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0906573A1 (de) | 1999-04-07 |
US5874233A (en) | 1999-02-23 |
CA2251567A1 (en) | 1997-10-23 |
DE69735100T2 (de) | 2006-08-31 |
AU2991697A (en) | 1997-11-07 |
CA2251567C (en) | 2009-07-07 |
WO1997039356A1 (en) | 1997-10-23 |
IL126534A (en) | 2005-07-25 |
IL126534A0 (en) | 1999-08-17 |
EP0906573A4 (de) | 2004-06-16 |
EP0906573B1 (de) | 2006-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |