DE69734451D1 - Skorpion-spezifische neuropeptide - Google Patents

Skorpion-spezifische neuropeptide

Info

Publication number
DE69734451D1
DE69734451D1 DE69734451T DE69734451T DE69734451D1 DE 69734451 D1 DE69734451 D1 DE 69734451D1 DE 69734451 T DE69734451 T DE 69734451T DE 69734451 T DE69734451 T DE 69734451T DE 69734451 D1 DE69734451 D1 DE 69734451D1
Authority
DE
Germany
Prior art keywords
cys
lys
arg
pro
scorpion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69734451T
Other languages
English (en)
Other versions
DE69734451T2 (de
Inventor
Bruno Lebrun
Regine Romi-Lebrun
Hiroyuki Minakata
Terumi Nakajima
Junko Hashino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DE69734451D1 publication Critical patent/DE69734451D1/de
Publication of DE69734451T2 publication Critical patent/DE69734451T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69734451T 1996-12-26 1997-12-25 Skorpion-spezifische neuropeptide Expired - Lifetime DE69734451T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP35981596 1996-12-26
JP35981596 1996-12-26
JP31287197 1997-10-30
JP31287197 1997-10-30
PCT/JP1997/004810 WO1998029446A1 (fr) 1996-12-26 1997-12-25 Neuropeptides provenant du scorpion

Publications (2)

Publication Number Publication Date
DE69734451D1 true DE69734451D1 (de) 2005-12-01
DE69734451T2 DE69734451T2 (de) 2006-07-13

Family

ID=26567350

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69734451T Expired - Lifetime DE69734451T2 (de) 1996-12-26 1997-12-25 Skorpion-spezifische neuropeptide

Country Status (8)

Country Link
US (1) US6689749B1 (de)
EP (1) EP0916681B1 (de)
JP (1) JP4212651B2 (de)
AT (1) ATE307829T1 (de)
CA (1) CA2247328C (de)
DE (1) DE69734451T2 (de)
ES (1) ES2247642T3 (de)
WO (1) WO1998029446A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7833979B2 (en) * 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
WO2007137163A2 (en) 2006-05-19 2007-11-29 Georgia Tech Research Corporation Abc transporter ligand
US8324158B2 (en) * 2006-07-14 2012-12-04 Georgia Tech Research Corporation Methods for inhibiting CLC-2 channel with GATX2
CA2667678A1 (en) 2006-10-25 2008-07-24 Amgen Inc. Toxin peptide therapeutic agents
AU2007353147B2 (en) 2007-05-14 2014-04-03 Universidad Nacional Autonoma De Mexico Vm23 and Vm24, two scorpion peptides that block human T-lymphocyte potassium channels (sub-type Kv1.3) with high selectivity and decrease the in vivo DTH-responses in rats
CA2687141C (en) 2007-05-22 2014-04-01 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
WO2010108153A2 (en) 2009-03-20 2010-09-23 Amgen Inc. Carrier immunoglobulins and uses thereof
EP2725034B1 (de) 2010-09-22 2019-04-03 Amgen Inc. Trägerimmunglobuline die nicht an humane Gewebe binden und Verwendungen davon
AU2012228990B2 (en) 2011-03-16 2017-04-06 Amgen Inc. Potent and selective inhibitors of Nav1.3 and Nav1.7
UY35397A (es) 2013-03-12 2014-10-31 Amgen Inc INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7
WO2015061826A1 (en) * 2013-10-28 2015-05-07 Monash University Novel scorpion toxin analogue and method for treating autoimmune diseases
US10668130B2 (en) 2017-03-31 2020-06-02 Vivekananda Ramana Formulation for targeting cancer in humans and canines using chlorotoxin
US10668112B2 (en) 2017-03-31 2020-06-02 Vivekananda Ramana Formulation for targeting cancer in humans and canines
US10668113B2 (en) 2017-03-31 2020-06-02 Vivekananda Ramana Formulation for targeting cancer in humans and canines using venom

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494895A (en) * 1993-07-22 1996-02-27 Merck & Co., Inc. Scorpion peptide margatoxin with immunosuppressant activity

Also Published As

Publication number Publication date
ES2247642T3 (es) 2006-03-01
EP0916681B1 (de) 2005-10-26
JP4212651B2 (ja) 2009-01-21
EP0916681A1 (de) 1999-05-19
US6689749B1 (en) 2004-02-10
CA2247328A1 (en) 1998-07-09
CA2247328C (en) 2007-01-30
DE69734451T2 (de) 2006-07-13
ATE307829T1 (de) 2005-11-15
WO1998029446A1 (fr) 1998-07-09
EP0916681A4 (de) 2003-01-02

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