DE69733773D1 - Fas ANTIGEN-DERIVATE - Google Patents
Fas ANTIGEN-DERIVATEInfo
- Publication number
- DE69733773D1 DE69733773D1 DE69733773T DE69733773T DE69733773D1 DE 69733773 D1 DE69733773 D1 DE 69733773D1 DE 69733773 T DE69733773 T DE 69733773T DE 69733773 T DE69733773 T DE 69733773T DE 69733773 D1 DE69733773 D1 DE 69733773D1
- Authority
- DE
- Germany
- Prior art keywords
- fas antigen
- amino acid
- derivative
- antigen derivative
- fas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010052621 fas Receptor Proteins 0.000 title abstract 8
- 102000018823 fas Receptor Human genes 0.000 title abstract 8
- 102000053602 DNA Human genes 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 125000000729 N-terminal amino-acid group Chemical group 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13576096 | 1996-05-02 | ||
| JP13576096 | 1996-05-02 | ||
| PCT/JP1997/001502 WO1997042319A1 (fr) | 1996-05-02 | 1997-05-01 | NOUVEAUX DERIVES DE L'ANTIGENE Fas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69733773D1 true DE69733773D1 (de) | 2005-08-25 |
| DE69733773T2 DE69733773T2 (de) | 2006-04-20 |
Family
ID=15159230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69733773T Expired - Lifetime DE69733773T2 (de) | 1996-05-02 | 1997-05-01 | Fas ANTIGEN-DERIVATE |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6306395B1 (de) |
| EP (1) | EP0965637B1 (de) |
| AT (1) | ATE299936T1 (de) |
| AU (1) | AU2650597A (de) |
| CA (1) | CA2253494A1 (de) |
| DE (1) | DE69733773T2 (de) |
| WO (1) | WO1997042319A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999024069A1 (fr) | 1997-11-10 | 1999-05-20 | Mochida Pharmaceutical Co., Ltd. | Medicaments preventifs et therapeutiques pour des affections pulmonaires diffuses |
| DE69935976D1 (de) * | 1998-05-14 | 2007-06-14 | Mochida Pharm Co Ltd | Prävention und therapie von leberzirrhosen |
| CA2333880A1 (en) | 1998-05-29 | 1999-12-09 | Mochida Pharmaceutical Co., Ltd. | Preventives/remedies for autoimmune demyelinating diseases |
| US20050037969A1 (en) * | 1999-05-14 | 2005-02-17 | Arbor Vita Corporation | Molecular interactions in hematopoietic cells |
| US6942981B1 (en) * | 1999-05-14 | 2005-09-13 | Arbor Vita Corporation | Method of determining interactions with PDZ-domain polypeptides |
| AU783960B2 (en) * | 1999-06-07 | 2006-01-05 | Immunex Corporation | Tek antagonists |
| US7087411B2 (en) * | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| US20070129291A1 (en) * | 2001-08-01 | 2007-06-07 | Genset S.A. | Genobix agonists and antagonists for use in the treatment of metabolic disorders |
| GB2381122B (en) * | 2001-10-16 | 2006-04-05 | Zetex Plc | Termination structure for a semiconductor device |
| AU2003278833A1 (en) * | 2002-09-19 | 2004-04-08 | Cornell Research Foundation, Inc. | Homing peptides to receptors of heart vasculature |
| PL1606318T3 (pl) | 2003-03-26 | 2010-01-29 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Ulepszone białka fuzyjne FC |
| WO2008080623A2 (en) | 2006-12-28 | 2008-07-10 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Neutralization of cd95 activity blocks invasion of glioblastoma cells in vivo |
| US20090196868A1 (en) * | 2007-09-06 | 2009-08-06 | Apogenix Gmbh | Methods and compositions for preventing radiation-induced pneumonitis |
| SI2697257T1 (sl) | 2011-04-13 | 2017-02-28 | Bristol-Myers Squibb Company | FC fuzijski proteini, ki vsebujejo nove linkerje ali razmestitve |
| SI2874659T1 (sl) | 2012-07-18 | 2016-11-30 | Apogenix Ag | Inhibitorji signalizirane poti CD95 za zdravljenje MDS |
| EP2875044B1 (de) | 2012-07-18 | 2018-04-11 | Apogenix AG | Fusionprotein, welches ein funktionelles fragment der n-terminal verkürzten extrazellulären domäne von cd95 enthält, das direkt an eine human fc domäne gekoppelt ist. |
| EP3076179A1 (de) | 2015-03-30 | 2016-10-05 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Diagnose und behandlung von minderwertigen glioma |
| AU2020256125A1 (en) | 2019-03-29 | 2021-11-18 | Turnstone Biologics Corp. | Ex vivo methods for producing a T cell therapeutic and related compositions and methods |
| EP4065229A1 (de) | 2019-11-27 | 2022-10-05 | Myst Therapeutics, LLC | Verfahren zur herstellung von tumorreaktiven t-zell-zusammensetzungen unter verwendung modulatorischer mittel |
| KR20220158727A (ko) | 2020-02-27 | 2022-12-01 | 미스트 쎄라퓨틱스, 엘엘씨 | 종양 반응성 t 세포의 생체외 농축 및 확장 방법 및 이의 관련 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| CA2067031C (en) * | 1991-04-26 | 2003-02-18 | Shigekazu Nagata | Dna coding for human cell surface antigen |
| US5770197A (en) * | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
| JPH08127594A (ja) * | 1993-11-10 | 1996-05-21 | Mochida Pharmaceut Co Ltd | Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ |
| JPH07289266A (ja) * | 1994-04-21 | 1995-11-07 | Mochida Pharmaceut Co Ltd | ヒトＦａｓ抗原バリアント及びそれをコードする新規ＤＮＡ |
-
1997
- 1997-05-01 AT AT97918354T patent/ATE299936T1/de not_active IP Right Cessation
- 1997-05-01 US US09/180,100 patent/US6306395B1/en not_active Expired - Fee Related
- 1997-05-01 AU AU26505/97A patent/AU2650597A/en not_active Abandoned
- 1997-05-01 WO PCT/JP1997/001502 patent/WO1997042319A1/ja active IP Right Grant
- 1997-05-01 DE DE69733773T patent/DE69733773T2/de not_active Expired - Lifetime
- 1997-05-01 EP EP97918354A patent/EP0965637B1/de not_active Expired - Lifetime
- 1997-05-01 CA CA002253494A patent/CA2253494A1/en not_active Abandoned
-
2001
- 2001-09-12 US US09/949,713 patent/US6953847B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0965637A1 (de) | 1999-12-22 |
| WO1997042319A1 (fr) | 1997-11-13 |
| DE69733773T2 (de) | 2006-04-20 |
| US20020044944A1 (en) | 2002-04-18 |
| ATE299936T1 (de) | 2005-08-15 |
| AU2650597A (en) | 1997-11-26 |
| CA2253494A1 (en) | 1997-11-13 |
| EP0965637B1 (de) | 2005-07-20 |
| US6306395B1 (en) | 2001-10-23 |
| US6953847B2 (en) | 2005-10-11 |
| EP0965637A4 (de) | 2002-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |