DE69732711D1 - Gamma-heregulin - Google Patents
Gamma-heregulinInfo
- Publication number
- DE69732711D1 DE69732711D1 DE69732711T DE69732711T DE69732711D1 DE 69732711 D1 DE69732711 D1 DE 69732711D1 DE 69732711 T DE69732711 T DE 69732711T DE 69732711 T DE69732711 T DE 69732711T DE 69732711 D1 DE69732711 D1 DE 69732711D1
- Authority
- DE
- Germany
- Prior art keywords
- adhesins
- chimeric
- erbb2
- heteromultimer
- heteromultimeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010089491 gamma-heregulin Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000014413 Neuregulin Human genes 0.000 abstract 1
- 108050003475 Neuregulin Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000002860 competitive effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/971—Capture of complex after antigen-antibody reaction
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2164096P | 1996-07-12 | 1996-07-12 | |
US21640P | 1996-07-12 | ||
PCT/US1997/011841 WO1998002541A1 (en) | 1996-07-12 | 1997-07-08 | Gamma-heregulin |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69732711D1 true DE69732711D1 (de) | 2005-04-14 |
DE69732711T2 DE69732711T2 (de) | 2006-03-16 |
Family
ID=21805329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69732711T Expired - Lifetime DE69732711T2 (de) | 1996-07-12 | 1997-07-08 | Gamma-heregulin |
Country Status (8)
Country | Link |
---|---|
US (6) | US6096873A (de) |
JP (2) | JP4382879B2 (de) |
AT (1) | ATE290595T1 (de) |
AU (1) | AU727606B2 (de) |
CA (1) | CA2257839C (de) |
DE (1) | DE69732711T2 (de) |
IL (4) | IL127892A0 (de) |
WO (1) | WO1998002541A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5834229A (en) | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
AU727606B2 (en) * | 1996-07-12 | 2000-12-14 | Genentech Inc. | Gamma-heregulin |
US20010023241A1 (en) | 1998-02-04 | 2001-09-20 | Sliwkowski Mark X. | Use of heregulin as a growth factor |
WO2000035474A1 (en) * | 1998-12-11 | 2000-06-22 | Khurana Tejvir S | Neurite derived growth factors for use in the treatment of muscular dystrophy |
AUPP785098A0 (en) | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
US6635249B1 (en) * | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
US7041292B1 (en) | 1999-06-25 | 2006-05-09 | Genentech, Inc. | Treating prostate cancer with anti-ErbB2 antibodies |
US6949245B1 (en) * | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
US20040013667A1 (en) * | 1999-06-25 | 2004-01-22 | Genentech, Inc. | Treatment with anti-ErbB2 antibodies |
US20030086924A1 (en) * | 1999-06-25 | 2003-05-08 | Genentech, Inc. | Treatment with anti-ErbB2 antibodies |
JP4579471B2 (ja) * | 1999-06-25 | 2010-11-10 | ジェネンテック, インコーポレイテッド | 抗ErbB2抗体を用いる前立腺癌の処置 |
EP2112167A3 (de) * | 1999-06-25 | 2010-12-22 | Genentech, Inc. | Humanisierte ANTI-ERBB2-Antikörper und Behandlung mit ANTI-ERBB2-Antikörpern |
HUP0301349A3 (en) * | 1999-07-15 | 2005-12-28 | Genetics Inst Llc Cambridge | Formulations for il-11 |
ATE438411T1 (de) * | 1999-08-27 | 2009-08-15 | Genentech Inc | Dosierung für die behandlung mit anti erbb2- antikörpern |
ATE441433T1 (de) * | 2000-05-19 | 2009-09-15 | Genentech Inc | Gennachweisverfahren zur verbesserung der wahrscheinlichkeit einer wirkungsvollen antwort auf eine krebstherapie mit einem erbb- antagonisten |
US20020119148A1 (en) * | 2000-09-01 | 2002-08-29 | Gerritsen Mary E. | ErbB4 antagonists |
WO2002055704A2 (en) * | 2001-01-09 | 2002-07-18 | Curagen Corp | Proteins, polynucleotides encoding them and methods of using the same |
CA2455830C (en) * | 2001-07-31 | 2012-10-09 | Wayne State University | Hybrid proteins with neuregulin heparin-binding domain for targeting to heparan sulfate proteoglycans |
WO2003049693A2 (en) * | 2001-12-06 | 2003-06-19 | Wyeth | Method and composition for inducing weight loss |
AU2003230929A1 (en) * | 2002-04-12 | 2003-10-27 | Raven Biotechnologies, Inc. | Antibodies that bind to integrin alpha-v-beta-6 and methods of use thereof |
AU2002304965A1 (en) * | 2002-05-24 | 2003-12-12 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
AU2003295798B2 (en) * | 2002-11-21 | 2009-09-10 | Genentech, Inc. | Therapy of non-malignant diseases or disorders with anti-ErbB2 antibodies |
ATE409484T1 (de) * | 2002-12-17 | 2008-10-15 | Centre Nat Rech Scient | Verwendung von purinderivaten zur induktion der differenzierung überzähliger haarzellen und deiter-zellen im entwickelnden corti-organ zur behandlung von taubheit |
SE0301087D0 (sv) * | 2003-04-14 | 2003-04-14 | Cartela Ab | New monoclonal antibody |
US20070213264A1 (en) | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
EP1981525B1 (de) * | 2005-12-30 | 2015-01-21 | Zensun (Shanghai) Science and Technology Limited | Verlängerte freisetzung von neuregulin für verbesserte herzfunktion |
US20090304590A1 (en) * | 2007-05-29 | 2009-12-10 | Wyeth | Therapeutic compositions and methods |
WO2008150485A2 (en) * | 2007-05-29 | 2008-12-11 | Wyeth | Erbb2 binding proteins and use thereof |
US8362215B2 (en) | 2009-04-29 | 2013-01-29 | Trellis Bioscience, Llc | Antibodies immunoreactive with heregulin-coupled HER3 |
KR101186218B1 (ko) | 2009-08-21 | 2012-10-08 | 경희대학교 산학협력단 | 히레귤린 베타1의 egf-성 도메인 펩타이드의 용도 |
NZ599499A (en) * | 2009-10-14 | 2014-06-27 | Acorda Therapeutics Inc | Use of a neuregulin to treat peripheral nerve injury |
WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun (Shanghai)Science & Technology Limited | Compositions and methods for treating heart failure |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4676980A (en) * | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
US4968603A (en) * | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
US5336603A (en) * | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
PT88641B (pt) | 1987-10-02 | 1993-04-30 | Genentech Inc | Metodo para a preparacao de uma variante de adesao |
US5283187A (en) * | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
US4892538A (en) * | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
EP0452364B1 (de) * | 1988-12-22 | 2002-05-22 | Genentech, Inc. | Verfahren zur herstellung von wasserlöslichen polypeptiden |
US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
EP0479909B1 (de) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Bispezifische reagenzien für die aids-therapie |
US5183884A (en) * | 1989-12-01 | 1993-02-02 | United States Of America | Dna segment encoding a gene for a receptor related to the epidermal growth factor receptor |
EP0444961A1 (de) * | 1990-03-02 | 1991-09-04 | Bristol-Myers Squibb Company | Her3: Ein neues EGF-Rezeptor Homologes |
NO921040L (no) * | 1991-03-17 | 1992-09-18 | Yeda Res & Dev | Stimulerende faktor for neu-reseptoren |
US5716930A (en) * | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
GB9107566D0 (en) * | 1991-04-10 | 1991-05-29 | Ludwig Inst Cancer Res | Glial mitogenic factors,their preparation and use |
US7115554B1 (en) * | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
US5530109A (en) * | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
US5367060A (en) * | 1991-05-24 | 1994-11-22 | Genentech, Inc. | Structure, production and use of heregulin |
IL101943A0 (en) * | 1991-05-24 | 1992-12-30 | Genentech Inc | Structure,production and use of heregulin |
US5635177A (en) | 1992-01-22 | 1997-06-03 | Genentech, Inc. | Protein tyrosine kinase agonist antibodies |
WO1993016178A2 (en) * | 1992-02-12 | 1993-08-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Sequences characteristic of human gene transcription product |
US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
WO1993022424A1 (en) * | 1992-04-29 | 1993-11-11 | Amgen Inc. | RECOMBINANT STIMULATING FACTOR OF THE neu RECEPTOR |
GB9217316D0 (en) * | 1992-08-14 | 1992-09-30 | Ludwig Inst Cancer Res | Schwann cell mitogenic factor,its preparation and use |
WO1994004690A1 (en) | 1992-08-17 | 1994-03-03 | Genentech, Inc. | Bispecific immunoadhesins |
CA2145769A1 (en) * | 1992-09-29 | 1994-04-14 | Gerald D. Fischbach | Trophic factor having ion channel-inducing activity in neuronal cells |
CA2103323A1 (en) * | 1992-11-24 | 1994-05-25 | Gregory D. Plowman | Her4 human receptor tyrosine kinase |
WO1994028133A1 (en) * | 1993-05-21 | 1994-12-08 | Amgen Inc. | Recombinant neu differentiation factors |
WO1995002052A1 (en) * | 1993-07-06 | 1995-01-19 | F. Hoffmann-La Roche Ag | Mammamodulin, a hormone-independent mammary tumor cells specific protein |
ES2116066T3 (es) | 1993-11-23 | 1998-07-01 | Genentech Inc | Ensayo de activacion del receptor quinasa. |
US5844092A (en) | 1994-03-18 | 1998-12-01 | Genentech, Inc. | Human TRK receptors and neurotrophic factor inhibitors |
US5804396A (en) * | 1994-10-12 | 1998-09-08 | Sugen, Inc. | Assay for agents active in proliferative disorders |
US5731168A (en) * | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
AU727606B2 (en) * | 1996-07-12 | 2000-12-14 | Genentech Inc. | Gamma-heregulin |
-
1997
- 1997-07-08 AU AU37208/97A patent/AU727606B2/en not_active Expired
- 1997-07-08 WO PCT/US1997/011841 patent/WO1998002541A1/en active Application Filing
- 1997-07-08 CA CA2257839A patent/CA2257839C/en not_active Expired - Lifetime
- 1997-07-08 IL IL12789297A patent/IL127892A0/xx active IP Right Grant
- 1997-07-08 DE DE69732711T patent/DE69732711T2/de not_active Expired - Lifetime
- 1997-07-08 JP JP50609398A patent/JP4382879B2/ja not_active Expired - Lifetime
- 1997-07-08 AT AT97934059T patent/ATE290595T1/de not_active IP Right Cessation
- 1997-07-10 US US08/891,845 patent/US6096873A/en not_active Expired - Lifetime
-
1998
- 1998-12-31 IL IL127892A patent/IL127892A/en not_active IP Right Cessation
-
2000
- 2000-02-28 US US09/514,573 patent/US6500941B1/en not_active Expired - Lifetime
-
2002
- 2002-11-08 US US10/290,578 patent/US6916624B2/en not_active Expired - Lifetime
-
2005
- 2005-07-01 US US11/173,893 patent/US7585673B2/en not_active Expired - Fee Related
-
2008
- 2008-04-27 IL IL191078A patent/IL191078A/en not_active IP Right Cessation
- 2008-04-27 IL IL191077A patent/IL191077A/en not_active IP Right Cessation
- 2008-07-03 US US12/168,032 patent/US20090042797A1/en not_active Abandoned
-
2009
- 2009-07-22 JP JP2009171357A patent/JP2009235108A/ja not_active Withdrawn
- 2009-12-16 US US12/639,822 patent/US8226935B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IL191077A (en) | 2011-12-29 |
US6096873A (en) | 2000-08-01 |
JP4382879B2 (ja) | 2009-12-16 |
IL127892A (en) | 2008-08-07 |
WO1998002541A1 (en) | 1998-01-22 |
ATE290595T1 (de) | 2005-03-15 |
CA2257839C (en) | 2012-10-23 |
IL191078A (en) | 2011-12-29 |
US8226935B2 (en) | 2012-07-24 |
AU727606B2 (en) | 2000-12-14 |
CA2257839A1 (en) | 1998-01-22 |
US6916624B2 (en) | 2005-07-12 |
IL191077A0 (en) | 2008-11-03 |
US20030078389A1 (en) | 2003-04-24 |
US20090042797A1 (en) | 2009-02-12 |
US7585673B2 (en) | 2009-09-08 |
US20060029602A1 (en) | 2006-02-09 |
IL191078A0 (en) | 2008-11-03 |
JP2009235108A (ja) | 2009-10-15 |
JP2000515740A (ja) | 2000-11-28 |
US20100135957A1 (en) | 2010-06-03 |
IL127892A0 (en) | 1999-10-28 |
DE69732711T2 (de) | 2006-03-16 |
US6500941B1 (en) | 2002-12-31 |
AU3720897A (en) | 1998-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |