DE69728690D1 - PISTON AND A LIQUID CHAMBER FOR A NOZZLE ARRANGEMENT - Google Patents

PISTON AND A LIQUID CHAMBER FOR A NOZZLE ARRANGEMENT

Info

Publication number
DE69728690D1
DE69728690D1 DE69728690T DE69728690T DE69728690D1 DE 69728690 D1 DE69728690 D1 DE 69728690D1 DE 69728690 T DE69728690 T DE 69728690T DE 69728690 T DE69728690 T DE 69728690T DE 69728690 D1 DE69728690 D1 DE 69728690D1
Authority
DE
Germany
Prior art keywords
injector
nozzle assembly
piston
locking mechanism
liquid chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69728690T
Other languages
German (de)
Other versions
DE69728690T2 (en
Inventor
David Schiff
Paul Mulhauser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antrares Pharma Inc Minneapolis Minn Us
Original Assignee
Medi Ject Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/773,660 external-priority patent/US5921967A/en
Application filed by Medi Ject Corp filed Critical Medi Ject Corp
Application granted granted Critical
Publication of DE69728690D1 publication Critical patent/DE69728690D1/en
Publication of DE69728690T2 publication Critical patent/DE69728690T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5066Means for preventing re-use by disconnection of piston and piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31516Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5066Means for preventing re-use by disconnection of piston and piston-rod
    • A61M2005/5073Means for preventing re-use by disconnection of piston and piston-rod by breaking or rupturing the connection parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515Connection of piston with piston rod

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Nozzles (AREA)
  • Injection Moulding Of Plastics Or The Like (AREA)
  • Details Or Accessories Of Spraying Plant Or Apparatus (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

The present invention is directed toward a locking mechanism for aiding in the prevention of accidental or unintentional disengagement of the nozzle assembly from a needleless injection device. In one embodiment of the locking mechanism, a stud positioned on the nozzle assembly engages a recess in the injector to help to deter the nozzle assembly from rotating during firing of the injector. In another embodiment of the locking mechanism, a nib on the nozzle assembly engages a recess in the injector to deter the nozzle assembly from rotating during firing of the injector. A retaining element may be utilized within the injector to provide the recesses for engagement with the locking mechanisms.
DE69728690T 1996-12-24 1997-12-22 PISTON AND A LIQUID CHAMBER FOR A NOZZLE ARRANGEMENT Expired - Lifetime DE69728690T2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/773,660 US5921967A (en) 1996-02-29 1996-12-24 Plunger for nozzle assembly
US773660 1996-12-24
US08/773,659 US5875976A (en) 1996-12-24 1996-12-24 Locking mechanism for nozzle assembly
PCT/US1997/023860 WO1998028030A1 (en) 1996-12-24 1997-12-22 Plunger for nozzle assembly

Publications (2)

Publication Number Publication Date
DE69728690D1 true DE69728690D1 (en) 2004-05-19
DE69728690T2 DE69728690T2 (en) 2005-08-18

Family

ID=41172495

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69728690T Expired - Lifetime DE69728690T2 (en) 1996-12-24 1997-12-22 PISTON AND A LIQUID CHAMBER FOR A NOZZLE ARRANGEMENT

Country Status (10)

Country Link
US (1) US5875976A (en)
EP (1) EP0954344B1 (en)
JP (1) JP4014115B2 (en)
CN (1) CN1247475A (en)
AT (1) ATE264124T1 (en)
AU (2) AU5620098A (en)
DE (1) DE69728690T2 (en)
ES (1) ES2231904T4 (en)
TW (1) TW391882B (en)
WO (2) WO1998028030A1 (en)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
WO2000071185A2 (en) * 1999-05-19 2000-11-30 Weston Medical Ltd Needleless injector drug capsule
ES2152086T3 (en) 1996-04-02 2001-01-16 Weston Medical Ltd PROCEDURE TO COMPLETE A CAPSULE WITH A MEDICINAL PRODUCT AND ARTICLE PRODUCED THIS WAY.
GB9714036D0 (en) * 1997-07-02 1997-09-10 Lucas Ind Plc Injector arrangement
US6409221B1 (en) 1999-06-17 2002-06-25 Phoenix Geometrix, Llc Quick locking pipe joint for round, plain, or profiled pipe
US6673035B1 (en) * 1999-10-22 2004-01-06 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US7914470B2 (en) * 2001-01-12 2011-03-29 Celleration, Inc. Ultrasonic method and device for wound treatment
US8235919B2 (en) * 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
WO2002061316A2 (en) 2001-02-01 2002-08-08 Phoenix Geometrix Llc Quick locking pipe joint for plain or profiled pipe
US7235063B2 (en) * 2001-08-21 2007-06-26 D'antonio Consultants International, Inc. Hypodermic injection system
GB0125506D0 (en) * 2001-10-24 2001-12-12 Weston Medical Ltd Needle free injection method and apparatus
EP1455870B1 (en) * 2001-12-06 2007-08-08 Novo Nordisk A/S A medical delivery system
WO2003068290A2 (en) 2002-02-11 2003-08-21 Antares Pharma, Inc. Intradermal injector
GB0224505D0 (en) * 2002-10-22 2002-11-27 Medical House The Plc Needles injection device
US6994382B2 (en) * 2004-07-01 2006-02-07 Visteon Global Technologies, Inc. Retaining feature for corrugated acoustic duct
JP4778694B2 (en) * 2004-09-14 2011-09-21 パナソニック株式会社 Semiconductor integrated circuit
BRPI0614025A2 (en) 2005-01-24 2012-12-25 Antares Pharma Inc jet injectors
US20120029471A1 (en) * 2010-07-30 2012-02-02 Lee Martin N Two chamber syringe with locking mechanism
US8529517B2 (en) * 2005-05-02 2013-09-10 Shi Zi Technology, Ltd. Autoflush syringe
US8936577B2 (en) 2005-05-02 2015-01-20 Shi Zi Technology, Ltd. Methods and devices for autoflush syringes
US8551045B2 (en) * 2006-04-19 2013-10-08 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system
EP2010256A1 (en) * 2006-04-19 2009-01-07 Novo Nordisk A/S A fluid infusion system, a method of assembling such system and drug reservoir for use in the system
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
US8540683B2 (en) * 2006-10-09 2013-09-24 Acist Medical Systems, Inc. Syringe device and injector system including a vent for relieving a vacuum within a syringe
US8491521B2 (en) * 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
US20080214965A1 (en) * 2007-01-04 2008-09-04 Celleration, Inc. Removable multi-channel applicator nozzle
US8617099B2 (en) * 2007-11-26 2013-12-31 Bioject Inc. Injection device plunger auto-disable
US20090137949A1 (en) * 2007-11-26 2009-05-28 Bioject Inc. Needle-free injection device with nozzle auto-disable
US20090177123A1 (en) * 2007-12-28 2009-07-09 Celleration, Inc. Methods for treating inflammatory disorders
US20100022919A1 (en) * 2008-07-22 2010-01-28 Celleration, Inc. Methods of Skin Grafting Using Ultrasound
ES2738539T3 (en) 2008-08-05 2020-01-23 Antares Pharma Inc Multi dose injector
US8613730B2 (en) * 2008-11-26 2013-12-24 Acist Medical Systems, Inc. Apparatus and methods for fluid pressurizing units of injection systems
US8114202B2 (en) * 2009-03-09 2012-02-14 Crane Environmental, Inc. Deaerator spray nozzle and related methods
AU2010226442A1 (en) 2009-03-20 2011-10-13 Antares Pharma, Inc. Hazardous agent injection system
WO2010125123A1 (en) 2009-04-30 2010-11-04 Dow Corning Corporation Elastomer compositions modified by silanes
JP5362451B2 (en) 2009-06-11 2013-12-11 オーエスジー株式会社 Machining head replaceable rotary tool, holder, and machining head
US8439593B2 (en) * 2009-11-10 2013-05-14 Imds Corporation Quarter turn locking mechanism
EP2332602A1 (en) * 2009-12-09 2011-06-15 F. Hoffmann-La Roche AG Container for receiving liquids
GB2481787A (en) * 2010-06-29 2012-01-11 Subsea 7 Ltd A method and apparatus for installing a buoy to an anchoring location
CN103582504B (en) * 2011-04-04 2016-04-27 艾迪国际研发有限公司 For the safety injection cylinder of needleless injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US8783736B2 (en) * 2011-07-21 2014-07-22 Kohler Co. Quick connector for faucet
EP4186545A1 (en) 2012-04-06 2023-05-31 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
WO2013169800A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Injection device with cammed ram assembly
ES2763633T3 (en) 2013-02-11 2020-05-29 Antares Pharma Inc Needle assisted jet injection device having reduced firing force
JP6030803B2 (en) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド Dose syringe with pinion system
US20140265313A1 (en) * 2013-03-13 2014-09-18 Boston Scientific Scimed, Inc. Instrument port attachment adapter
EP3074089A4 (en) 2013-11-26 2017-07-26 Alliqua Biomedical, Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
CN203646503U (en) * 2013-11-29 2014-06-18 刘秋明 Electronic cigarette device
UA122135C2 (en) * 2014-12-04 2020-09-25 Толмар Терап'Ютикс, Інк. Syringe plunger system with self-locking threaded geometry
US9791081B2 (en) * 2015-04-30 2017-10-17 Opw-Engineered Systems, Inc. Fluid system connection nozzle assembly
FR3048618B1 (en) * 2016-03-08 2018-04-13 Crossject NEEDLE-FREE INJECTION DEVICE EQUIPPED WITH AN IMPROVED INJECTION NOZZLE
US11033678B2 (en) 2017-11-20 2021-06-15 Agist Medical Systems, Inc. Compact injector drive
US11040147B2 (en) 2017-11-21 2021-06-22 Acist Medical Systems, Inc. Injector position sensing
WO2019123490A1 (en) * 2017-12-19 2019-06-27 Matex Lab S.P.A. Pusher unit for a syringe, and corresponding syringe
JP2019217105A (en) 2018-06-21 2019-12-26 株式会社松風 Injector
EP3851139A4 (en) * 2018-09-13 2022-06-15 Circulus Inc. Injection system, syringe, and gasket
WO2020085318A1 (en) * 2018-10-24 2020-04-30 株式会社サーキュラス Injection system, syringe, and gasket
US11992669B2 (en) * 2018-11-16 2024-05-28 Plas-Tech Engineering, Inc. Systems and methods related to syringes
US11207469B1 (en) * 2021-03-04 2021-12-28 Expressions Design Studio, LLC Low deadspace syringe including a pivoting needle guard

Family Cites Families (197)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123070A (en) * 1964-03-03 Multidose jet injector
US620821A (en) * 1899-03-07 Hose-coupling
US2704543A (en) * 1955-03-22 Hypo jet injector
US1311145A (en) * 1919-07-22 Coupling to be used eor pipe
US1629058A (en) * 1925-07-30 1927-05-17 Guiberson Corp Threaded coupling
US1645032A (en) * 1926-06-14 1927-10-11 Guiberson Corp Box and pin coupling
US2322244A (en) * 1940-03-18 1943-06-22 Marshall L Lockhart Hypodermic injector
US2390246A (en) * 1940-10-18 1945-12-04 Marvin L Folkman Syringe
US2322245A (en) * 1943-05-20 1943-06-22 Marshall L Lockhart Ypodermic injector and method of use thereof
US2380534A (en) * 1941-04-26 1945-07-31 Marshall L Lockhart Hypodermic injector
US2413303A (en) * 1944-01-17 1946-12-31 Marvin L Folkman Syringe
US2459875A (en) * 1944-09-11 1949-01-25 Marvin L Folkman Syringe and ampoule
US2398544A (en) * 1945-01-06 1946-04-16 Marshall L Lockhart Hypodermic injector
US2450527A (en) * 1945-10-27 1948-10-05 P & V Quicklocking Co Semiautomatic coupling
US2800903A (en) * 1947-07-30 1957-07-30 Becton Dickinson Co Injection apparatus
US2605763A (en) * 1948-01-31 1952-08-05 Becton Dickinson Co Injection device
US2547099A (en) * 1948-03-11 1951-04-03 Becton Dickinson Co Injection device and ampoule
US2704542A (en) * 1949-02-21 1955-03-22 Scherer Corp R P Jet therapy method
US2688968A (en) * 1949-05-14 1954-09-14 Scherer Corp R P Hypo jet ampoule
US2902994A (en) * 1949-05-21 1959-09-08 Scherer Corp R P Hypo jet injector
US2699166A (en) * 1949-07-29 1955-01-11 Becton Dickinson Co Hypodermic injection unit
US2798485A (en) * 1949-09-01 1957-07-09 Jr George N Hein Ampule
US2737946A (en) * 1949-09-01 1956-03-13 Jr George N Hein Hypodermic injection apparatus
US2653602A (en) * 1950-06-17 1953-09-29 Becton Dickinson Co Injection device
US2671347A (en) * 1950-06-24 1954-03-09 Scherer Corp R P Latch structure
US2754818A (en) * 1950-06-24 1956-07-17 Scherer Corp R P Hypo jet injector
US2681653A (en) * 1950-09-06 1954-06-22 Becton Dickinson Co Hypodermic injection orifice structure and method of making same
US2722931A (en) * 1951-01-17 1955-11-08 Becton Dickinson Co Injection device
US2670121A (en) * 1951-01-31 1954-02-23 Scherer Corp R P Flexible follower for metal ampoules
US2764977A (en) * 1951-05-24 1956-10-02 Becton Dickinson Co Hypodermic injection mechanism
US2635602A (en) * 1951-11-21 1953-04-21 Jr George N Hein Hypodermic injection apparatus
US2821193A (en) * 1952-07-22 1958-01-28 Geoffrey W Walker Multiple injection inoculator instrument
US2789839A (en) * 1952-08-27 1957-04-23 Bissell Carpet Sweeper Co Spring detent engaging means for carpet sweeper sectional handle
US2717597A (en) * 1952-12-04 1955-09-13 Jr George N Hein Injection apparatus
GB766431A (en) * 1953-02-11 1957-01-23 Nat Res Dev Improvements relating to hypodermic injection apparatus
FR1067076A (en) * 1953-12-16 1954-06-11 Hygiene Scient Hygiscient Lab Improvements to needleless parenteral injection devices
US2820655A (en) * 1953-12-18 1958-01-21 Collins Radio Co Tenacious fastener
US2798486A (en) * 1953-12-21 1957-07-09 Jr George N Hein Injection assembly
US2714887A (en) * 1954-04-26 1955-08-09 Scherer Corp R P Intradermal injector
US2816544A (en) * 1954-07-12 1957-12-17 Scherer Corp R P Hypodermic injector
US2816543A (en) * 1954-07-12 1957-12-17 Scherer Corp R P Hypodermic injector
US2821981A (en) * 1954-07-21 1958-02-04 Geoffrey W Walker Multi-shot inoculant injector instrument with adjustable ejection pressure control
US2825332A (en) * 1954-08-20 1958-03-04 Howard Johnson Electrostatics Hypodermic syringe with magnetically actuated piston and needle
US2762370A (en) * 1954-09-07 1956-09-11 Scherer Corp R P Hypodermic injector
US2762369A (en) * 1954-09-07 1956-09-11 Scherer Corp R P Hypodermic injector with adjustable impact plunger
US2896977A (en) * 1954-12-30 1959-07-28 Hansen Mfg Co Bayonet lock coupling
US3147967A (en) * 1956-06-27 1964-09-08 Bougeard Arthur Pneumatic shock absorber
NL106573C (en) * 1957-05-31
US2928390A (en) * 1957-07-15 1960-03-15 Scherer Corp R P Multi-dose hypodermic injector
US3057349A (en) 1959-12-14 1962-10-09 Ismach Aaron Multi-dose jet injection device
GB964585A (en) * 1960-03-23
GB995605A (en) * 1960-08-04 1965-06-23 Amalgamated Dental Co Ltd Improvements relating to hypodermic injection apparatus
DE1287743B (en) * 1960-08-15 1969-01-23
FR1072399A (en) * 1961-01-07 1954-09-13 Intra-dermal injector
US3138157A (en) * 1961-05-12 1964-06-23 Z & W Mfg Corp Inoculant injector instrument
US3167071A (en) * 1961-07-17 1965-01-26 Scherer Corp R P Apparatus for administering intradermal injections
US3115133A (en) * 1962-05-15 1963-12-24 Morando Emilio Donald Needleless prefilled disposable hypodermic injector
NL296017A (en) * 1962-08-03 1900-01-01
BE643768A (en) * 1963-02-18
US3140713A (en) * 1963-03-25 1964-07-14 Ismach Aaron Intradermal nozzle for jet injection devices
US3202151A (en) * 1963-04-08 1965-08-24 Scherer Corp R P Multidose jet injector
US3330276A (en) * 1963-10-07 1967-07-11 Scherer Corp R P Hypodermic jet injector
US3245703A (en) * 1963-10-28 1966-04-12 Robert S Manly Quick detachable pipe coupling
US3335722A (en) * 1963-11-01 1967-08-15 Olin Mathieson Hypodermic device
US3308818A (en) * 1964-07-24 1967-03-14 Eugene V Rutkowski Injection cartridge
US3330277A (en) * 1964-08-17 1967-07-11 Scherer Corp R P Multidose hypodermic injector
US3292622A (en) * 1964-09-21 1966-12-20 Oscar H Banker Power operated inoculator
US3406684A (en) * 1964-09-28 1968-10-22 Yuryo Kikakuhin Kenkyusho Kk Jet type, medical injection instrument
US3399759A (en) * 1964-11-19 1968-09-03 Express Injector Company Ltd Protecting holders
US3425413A (en) * 1965-04-30 1969-02-04 Amalgamated Dental Co Ltd Multi-dosage jet injector
US3343798A (en) * 1965-07-20 1967-09-26 Gen Motors Corp Injector clamp and index device
US3353537A (en) * 1965-08-11 1967-11-21 George W Knox Automatic multi-dosage inoculating instrument
US3424154A (en) * 1965-11-08 1969-01-28 Charles W Kinsley Injection system
US3461867A (en) * 1966-03-14 1969-08-19 Mizzy Inc Needleless injector
US3526225A (en) * 1967-03-31 1970-09-01 Tokyo Sokuhan Kk Jet-type hypodermic injection device
US3527212A (en) * 1967-09-13 1970-09-08 Wesley D Clark Disposable needleless hypodermic injector
US3521633A (en) * 1967-11-13 1970-07-28 Scherer Corp R P Brake device for hypodermic jet injector
US3490451A (en) * 1967-11-13 1970-01-20 Scherer Corp R P Hypodermic jet injector nozzle
US3476110A (en) * 1967-11-13 1969-11-04 Scherer Corp R P Crank for loading hypodermic jet injector
US3518990A (en) * 1968-05-02 1970-07-07 Oscar H Banker Gun type inoculator
US3442536A (en) * 1968-05-09 1969-05-06 Rockwell Mfg Co Pipe joint having circumferentially spaced teeth coupling means
US3507276A (en) * 1968-08-28 1970-04-21 Murray B Burgess Jet injector
US3561443A (en) * 1968-09-06 1971-02-09 Oscar H Banker Inoculator gun with delayed action
US3557784A (en) * 1968-12-24 1971-01-26 Walter A Shields Syringe
US3625208A (en) * 1969-05-19 1971-12-07 Mediquip Corp Apparatus for pressure-administering medicaments
US3688765A (en) * 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US3659587A (en) * 1970-06-30 1972-05-02 Affiliated Hospital Prod Valved connector arrangement
US3838689A (en) * 1970-11-04 1974-10-01 M Cohen Disposable syringe with slit valve
US3714943A (en) * 1970-12-01 1973-02-06 H Yanof Medicament injectors
US3805783A (en) * 1971-02-12 1974-04-23 A Ismach Hand powered hypodermic jet injector gun
US3788315A (en) * 1971-04-20 1974-01-29 S Laurens Disposable cutaneous transjector
US3783895A (en) * 1971-05-04 1974-01-08 Sherwood Medical Ind Inc Universal parenteral fluid administration connector
US3768472A (en) * 1972-02-07 1973-10-30 M Hodosh Fluid dispensing gun
US3779371A (en) * 1972-03-13 1973-12-18 W Rovinski Package of separated materials to be mixed
DE2254153A1 (en) 1972-11-04 1974-05-09 Werner Dipl Ing Kullmann Automatic universally applicable hypodermic syringe - for veterinary treat-ment of animals or for drugging them at long range
US3782380A (en) * 1973-01-04 1974-01-01 Gaast H V D Medicament injecting device
US3827601A (en) * 1973-03-23 1974-08-06 J Magrath Hand powered liquid dispenser of the metering type
CA1025601A (en) 1973-05-14 1978-02-07 David Dardick Open chamber gas powered tool and gas generating charge therefor
US3908651A (en) * 1974-05-17 1975-09-30 Daystrol Scient Inc Medicament injection device
US3938520A (en) * 1974-06-10 1976-02-17 Abbott Laboratories Transfer unit having a dual channel transfer member
US3945383A (en) * 1974-08-08 1976-03-23 Smithkline Corporation Unit dose ampul for jet injector
US3945379A (en) * 1974-08-08 1976-03-23 Smithkline Corporation Injection device
JPS51130094A (en) 1975-05-08 1976-11-12 Asahi Chemical Ind Twoostage pressure injector
US4141675A (en) 1975-12-22 1979-02-27 Physics International Company Gas-actuated fuel pump wherein the pump piston is driven by a spring
US4089334A (en) 1976-10-07 1978-05-16 Schwebel Paul R Pyrotechnically powered needleless injector
DE2817102C2 (en) 1978-04-19 1985-01-24 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg Connector for plastic cannulas or venous catheters
US4260180A (en) 1979-07-23 1981-04-07 Hughes Aircraft Company Mechanical coupling
US4328802A (en) 1980-05-14 1982-05-11 Survival Technology, Inc. Wet dry syringe package
GB2084704B (en) 1980-10-01 1983-06-29 Theobald David Reginald Air rifle
JPS57103947A (en) 1980-12-18 1982-06-28 Kuroda Precision Ind Ltd Pneumatic shock absorber
US4421508A (en) 1981-02-24 1983-12-20 Cohen Edgar C Vacuum-compression injector
US4406485A (en) 1981-04-27 1983-09-27 Arrowhead Continental Tubular connector
US4436519A (en) 1981-05-28 1984-03-13 Argon Medical Corp. Removable hemostasis valve
GB2108852A (en) * 1981-11-20 1983-05-25 Greater Glasgow Health Board Syringe
US4447225A (en) 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
CA1178503A (en) 1982-05-27 1984-11-27 Health-Mor Personal Care Corporation Needleless hypodermic injector
US4507113A (en) 1982-11-22 1985-03-26 Derata Corporation Hypodermic jet injector
US4505709A (en) 1983-02-22 1985-03-19 Froning Edward C Liquid transfer device
US4518385A (en) 1983-06-13 1985-05-21 Preci-Tech Ltd. Disposable syringe for needleless injector
HU186718B (en) 1983-06-29 1985-09-30 Radelkis Electrokemiai Automatic needleless syringe operable by cardox cylinder suitable for personal giving injection e.g. insulin
US4561856A (en) 1983-08-18 1985-12-31 Cochran Ulrich D Infusion pump
DE3444817A1 (en) 1984-01-20 1985-07-25 Rasmussen Gmbh, 6457 Maintal CONNECTOR
US4619651A (en) 1984-04-16 1986-10-28 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4588403A (en) 1984-06-01 1986-05-13 American Hospital Supply Corporation Vented syringe adapter assembly
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
GB2173287B (en) 1985-04-01 1988-08-10 Utec Bv Air weapon air compression system
US4616856A (en) 1985-04-25 1986-10-14 S&C Electric Company Nozzle and retaining arrangement
US4675020A (en) 1985-10-09 1987-06-23 Kendall Mcgaw Laboratories, Inc. Connector
US4662878A (en) 1985-11-13 1987-05-05 Patents Unlimited Ltd. Medicine vial adaptor for needleless injector
US4680027A (en) 1985-12-12 1987-07-14 Injet Medical Products, Inc. Needleless hypodermic injection device
US4744786A (en) 1986-06-17 1988-05-17 Cordis Corporation Infusion pump
EP0250022A3 (en) 1986-06-17 1988-06-22 SICIM SpA Portable endermic injector
US4799881A (en) 1986-10-16 1989-01-24 Grier-Mcguire Inc. "Twist-lock" gas nozzle for a heat treating furnace
WO1988004638A1 (en) 1986-12-17 1988-06-30 Microvol Limited Pressurised metering dispenser
US4722728A (en) 1987-01-23 1988-02-02 Patents Unlimited, Ltd. Needleless hypodermic injector
IT1217047B (en) 1987-03-19 1990-03-14 Cocchi Pietro INJECTION SYRINGE, INTRAVENOUS SPECIES, MADE TO BE USED ONLY ONCE, WITHOUT POSSIBILITY OF RE-INSPIRATION.
USD304616S (en) 1987-04-30 1989-11-14 Derata Corporation Medicament injector
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4768568A (en) 1987-07-07 1988-09-06 Survival Technology, Inc. Hazardous material vial apparatus providing expansible sealed and filter vented chambers
GB8722915D0 (en) 1987-09-30 1987-11-04 Braithwaite P W Syringes
US5073165A (en) 1988-02-05 1991-12-17 Marpam International, Inc. Hypodermic jet injector and cartridge therefor
US4874367A (en) 1988-02-05 1989-10-17 Marpam International, Inc. Hypodermic jet injector and cartridge therefor
US4913699A (en) 1988-03-14 1990-04-03 Parsons James S Disposable needleless injection system
ES2036714T3 (en) 1988-03-25 1993-06-01 Dematex Development & Trading Inc. C/O Quijano And Associates TUBE, PLUG AND COMPRESSION RING FOR BLOOD SAMPLING SYSTEMS.
US4931040A (en) * 1988-04-13 1990-06-05 Habley Medical Technology Safety syringe having a combination needle cannula and articulating hub for retracting said cannula into a medication carpule
US4869720A (en) * 1988-05-05 1989-09-26 E-Z-Em, Inc. Hypodermic syringe assembly
DE8806642U1 (en) 1988-05-20 1988-09-08 Stabilus Gmbh, 5400 Koblenz Piston rod seal of a gas spring
DE3818811A1 (en) 1988-06-03 1989-12-14 Stabilus Gmbh GAS SPRING WITH SEVERAL PRESSURE SPACES
US5024656A (en) 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US5224932A (en) 1988-09-27 1993-07-06 Venivee, Inc. System for intravenous administration of a plurality of medicaments and/or nutrients
JPH02212768A (en) 1989-02-13 1990-08-23 Terumo Corp Blood sampling tube
US5052725A (en) 1989-03-13 1991-10-01 Colder Products Company Two piece molded female coupling
US5188599A (en) 1989-07-11 1993-02-23 Med-Design, Inc. Retractable needle system
US5407431A (en) 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
DE3923513A1 (en) 1989-07-15 1991-01-24 Stabilus Gmbh METHOD AND DEVICE FOR INLETING PRESSURE GAS IN THE CONTAINER TUBE OF A PNEUMATIC SPRING OR THE LIKE
CA1325149C (en) 1989-08-31 1993-12-14 Gavin Mcgregor Variable intensity remote controlled needleless injector
AU6550990A (en) 1989-11-09 1991-05-16 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5031266A (en) 1989-12-21 1991-07-16 Whirlpool Corporation Vacuum cleaner wand seal
US4989905A (en) 1990-02-05 1991-02-05 Lamson & Sessions Co. Fitting for corrugated tubing
US5062830A (en) 1990-04-04 1991-11-05 Derata Corporation Dry disposable nozzle assembly for medical jet injector
CA2039681C (en) 1990-04-05 2001-02-20 Richard J. Hamilton Quick disconnect nozzle assembly
US5135507A (en) 1990-05-10 1992-08-04 Habley Medical Technology Corporation One-piece syringe
GB9012829D0 (en) 1990-06-08 1990-08-01 Bernard D J C Reduced diameter dummy piston
GB9017007D0 (en) 1990-08-02 1990-09-19 Bernard Derek J C Improvements to pre-charged pneumatic airguns
GB9020749D0 (en) 1990-09-24 1990-11-07 Bates William T D Improved single-use syringe
CA2032830C (en) 1990-12-20 1994-07-26 Robert Graham Straghan Coupling
GB9103291D0 (en) 1991-02-15 1991-04-03 Waverley Pharma Ltd Transfer adaptor
DE4110303A1 (en) 1991-03-28 1992-10-01 Pfeiffer Erich Gmbh & Co Kg DISCHARGE DEVICE FOR MEDIA
US5085332B1 (en) 1991-04-11 1994-04-05 Gettig Technologies Inc Closure assembly
US5423756A (en) 1991-04-13 1995-06-13 Van Der Merwe; Marius Syringe
IL98036A0 (en) 1991-05-02 1992-06-21 Yoav Cohen Plastic stand pipe support for load-bearing adjustable piston
US5141157A (en) 1991-08-01 1992-08-25 Anthony Mfg. Corp., Industrial Div. Vandal resistant locking device for pop-up sprinkler nozzle housings
US5190523A (en) 1991-08-16 1993-03-02 Idee International R & D Inc. Disposable syringe and injector
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
DE4129271C1 (en) 1991-09-03 1992-09-17 Fresenius Ag, 6380 Bad Homburg, De
US5356380A (en) 1991-10-23 1994-10-18 Baxter International Inc. Drug delivery system
JP2772188B2 (en) 1992-01-23 1998-07-02 武蔵エンジニアリング株式会社 Liquid dispenser syringe plunger
US5209362A (en) 1992-01-24 1993-05-11 Lutzker Robert S Can resealer
US5165560A (en) 1992-03-26 1992-11-24 Genesis Industries, Inc. Nonrotating hermetically sealed closure for bottle containing liquid
US5312577A (en) 1992-05-08 1994-05-17 Bioject Inc. Method for manufacturing an ampule
JP2931715B2 (en) 1992-05-12 1999-08-09 三菱電機株式会社 Resin sealing method, resin sealing device, and gas spring
US5279576A (en) 1992-05-26 1994-01-18 George Loo Medication vial adapter
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
FR2694053B1 (en) 1992-07-24 1994-09-02 Souriau & Cie Bayonet type locking connection assembly.
USD349958S (en) 1992-07-24 1994-08-23 Bioject Inc. Needleless injector
US5304128A (en) 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
AU5293393A (en) 1992-09-28 1994-04-26 Equidyne Systems, Incorporated Hypodermic jet injector
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
TW245642B (en) * 1992-09-29 1995-04-21 Alza Corp
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
US5292308A (en) 1993-05-04 1994-03-08 Ryan Dana W Three piece intravenous line connector
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5643211A (en) 1996-02-29 1997-07-01 Medi-Ject Corporation Nozzle assembly having a frangible plunger

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TW391882B (en) 2000-06-01
WO1998030253A3 (en) 1998-10-22
AU5718398A (en) 1998-07-17
EP0954344A1 (en) 1999-11-10
AU5620098A (en) 1998-08-03
CN1247475A (en) 2000-03-15
DE69728690T2 (en) 2005-08-18
ES2231904T4 (en) 2007-10-16
JP2001507963A (en) 2001-06-19
ATE264124T1 (en) 2004-04-15
US5875976A (en) 1999-03-02
WO1998028030A1 (en) 1998-07-02
JP4014115B2 (en) 2007-11-28
EP0954344A4 (en) 2000-08-09
EP0954344B1 (en) 2004-04-14
ES2231904T3 (en) 2005-05-16
WO1998030253A2 (en) 1998-07-16

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Owner name: ANTRARES PHARMA INC., MINNEAPOLIS, MINN., US

8364 No opposition during term of opposition