DE69717991D1 - Ein monoklonaler antikörper, welcher ein apoptotisches antigen nachweist - Google Patents

Ein monoklonaler antikörper, welcher ein apoptotisches antigen nachweist

Info

Publication number
DE69717991D1
DE69717991D1 DE69717991T DE69717991T DE69717991D1 DE 69717991 D1 DE69717991 D1 DE 69717991D1 DE 69717991 T DE69717991 T DE 69717991T DE 69717991 T DE69717991 T DE 69717991T DE 69717991 D1 DE69717991 D1 DE 69717991D1
Authority
DE
Germany
Prior art keywords
antique
apoptotic
monoclonal antibody
antibody detecting
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69717991T
Other languages
English (en)
Other versions
DE69717991T2 (de
Inventor
Franklin Schlossman
Chonghui Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Original Assignee
Dana Farber Cancer Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Institute Inc filed Critical Dana Farber Cancer Institute Inc
Publication of DE69717991D1 publication Critical patent/DE69717991D1/de
Application granted granted Critical
Publication of DE69717991T2 publication Critical patent/DE69717991T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69717991T 1996-03-29 1997-03-28 Ein monoklonaler antikörper, welcher ein apoptotisches antigen nachweist Expired - Lifetime DE69717991T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/623,876 US5935801A (en) 1996-03-29 1996-03-29 Monoclonal antibody that detects apoptotic antigen
PCT/US1997/005157 WO1997036928A1 (en) 1996-03-29 1997-03-28 Monoclonal antibody that detects apoptotic antigen

Publications (2)

Publication Number Publication Date
DE69717991D1 true DE69717991D1 (de) 2003-01-30
DE69717991T2 DE69717991T2 (de) 2003-07-24

Family

ID=24499752

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69717991T Expired - Lifetime DE69717991T2 (de) 1996-03-29 1997-03-28 Ein monoklonaler antikörper, welcher ein apoptotisches antigen nachweist

Country Status (8)

Country Link
US (1) US5935801A (de)
EP (1) EP0904296B1 (de)
JP (1) JP2000509252A (de)
CN (1) CN1215406A (de)
AU (1) AU2596397A (de)
CA (1) CA2248615A1 (de)
DE (1) DE69717991T2 (de)
WO (1) WO1997036928A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323039B1 (en) * 1999-06-22 2001-11-27 Mitokor Compositions and methods for assaying subcellular conditions and processes using energy transfer
CA2397417A1 (en) * 2000-01-12 2001-07-19 Sarah S. Bacus Method for quantitating a protein by image analysis
WO2003042703A1 (en) * 2001-11-13 2003-05-22 Klaus-Michael Debatin Method of detecting apoptosis induction by measuring the release of substances from cell organelles by means of flow cytometry
WO2003044482A2 (en) * 2001-11-16 2003-05-30 The University Of Tennessee Research Corporation Recombinant antibody fusion proteins and methods for detection of apoptotic cells
EP2070949B1 (de) * 2002-06-10 2013-01-16 Vaccinex, Inc. C35-Antikörper und ihre Verwendung zur Behandlung von Krebs
JP5042631B2 (ja) * 2003-12-04 2012-10-03 バクシネックス インコーポレーティッド アポトーシス腫瘍細胞上に露出した細胞内抗原をターゲッティングすることによって腫瘍細胞を死滅させる方法
RU2450273C2 (ru) * 2006-06-20 2012-05-10 Дженентек, Инк. Способы и материалы для обнаружения апоптоза
AU2007261247A1 (en) * 2006-06-22 2007-12-27 Vaccinex, Inc. Anti-C35 antibodies for treating cancer
CN101932333A (zh) 2007-12-26 2010-12-29 瓦西尼斯公司 抗c35抗体联合疗法和方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0511202B1 (de) * 1990-01-19 1994-06-01 German Cancer Research Center Mit zellularer apoptosis assoziiertes zelloberflächenantigen
FR2674433A1 (fr) * 1991-03-27 1992-10-02 Pasteur Institut Medicament contenant un agent inhibant in vivo l'apoptose pathologique et applications.
CA2067031C (en) * 1991-04-26 2003-02-18 Shigekazu Nagata Dna coding for human cell surface antigen
JPH06109729A (ja) * 1992-09-30 1994-04-22 Nippon Koutai Kenkyusho:Kk アポトーシス検出試薬
US5646008A (en) * 1993-06-22 1997-07-08 The Regent Of The University Of Michigan Vertebrate apoptosis gene: compositions and methods
JPH0977794A (ja) * 1995-09-14 1997-03-25 Yasukazu Tanuma 新規タンパク質

Also Published As

Publication number Publication date
CA2248615A1 (en) 1997-10-09
DE69717991T2 (de) 2003-07-24
JP2000509252A (ja) 2000-07-25
WO1997036928A1 (en) 1997-10-09
CN1215406A (zh) 1999-04-28
EP0904296B1 (de) 2002-12-18
AU2596397A (en) 1997-10-22
EP0904296A1 (de) 1999-03-31
US5935801A (en) 1999-08-10

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Legal Events

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