DE69717490T2 - Nicht aggregierte fluoreszierende konjugate und verfahren zu ihrer herstellung - Google Patents

Nicht aggregierte fluoreszierende konjugate und verfahren zu ihrer herstellung

Info

Publication number
DE69717490T2
DE69717490T2 DE69717490T DE69717490T DE69717490T2 DE 69717490 T2 DE69717490 T2 DE 69717490T2 DE 69717490 T DE69717490 T DE 69717490T DE 69717490 T DE69717490 T DE 69717490T DE 69717490 T2 DE69717490 T2 DE 69717490T2
Authority
DE
Germany
Prior art keywords
agreed
production
fluorescent conjugates
carboxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69717490T
Other languages
English (en)
Other versions
DE69717490D1 (de
Inventor
Daniel Aspe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Application granted granted Critical
Publication of DE69717490D1 publication Critical patent/DE69717490D1/de
Publication of DE69717490T2 publication Critical patent/DE69717490T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Luminescent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Electroluminescent Light Sources (AREA)
DE69717490T 1996-12-12 1997-12-12 Nicht aggregierte fluoreszierende konjugate und verfahren zu ihrer herstellung Expired - Lifetime DE69717490T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615261A FR2757162B1 (fr) 1996-12-12 1996-12-12 Conjugues fluorescents non agreges
PCT/FR1997/002288 WO1998026287A1 (fr) 1996-12-12 1997-12-12 Conjugues fluorescents non agreges et leur procede d'obtention

Publications (2)

Publication Number Publication Date
DE69717490D1 DE69717490D1 (de) 2003-01-09
DE69717490T2 true DE69717490T2 (de) 2003-09-04

Family

ID=9498586

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69717490T Expired - Lifetime DE69717490T2 (de) 1996-12-12 1997-12-12 Nicht aggregierte fluoreszierende konjugate und verfahren zu ihrer herstellung

Country Status (9)

Country Link
EP (1) EP0946870B1 (de)
JP (1) JP3955638B2 (de)
AT (1) ATE228656T1 (de)
AU (1) AU5489498A (de)
CA (1) CA2272890C (de)
DE (1) DE69717490T2 (de)
ES (1) ES2187834T3 (de)
FR (1) FR2757162B1 (de)
WO (1) WO1998026287A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19731741A1 (de) * 1997-07-23 1999-01-28 Deutsches Krebsforsch Konjugat zur Unterscheidung von krankhaftem und gesundem Gewebe
EP0934986A1 (de) * 1997-12-17 1999-08-11 Roche Diagnostics GmbH Farbstoff-Polyaccharid- bzw. Cyclosaccharid-Konjugate und deren Verwendung als Diagnostikum
US6242430B1 (en) 1998-04-30 2001-06-05 Laboratory Of Molecular Biophotonics Cyclodextrin-based rotaxane dyes, labeling agent using the dye, and a method for labeling
DE10026623A1 (de) * 2000-05-29 2001-12-06 Heinz Langhals Perylenfarbstoffe mit persistenter Fluoreszenz durch sterische Aggregationshinderung
JP4235550B2 (ja) 2001-09-28 2009-03-11 キヤノン株式会社 有機発光素子
FR2840611B1 (fr) * 2002-06-06 2005-09-09 Cis Bio Int Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations
FR2878853B1 (fr) * 2004-12-07 2007-03-16 Biocydex Soc Par Actions Simpl Procede d'obtention d'un complexe fluorescent, complexe obtenu et utilisation
WO2007027159A1 (en) * 2005-08-30 2007-03-08 Agency For Science, Technology And Research Water-soluble fluorescent particle comprising entangled fluorescent polymer and amphiphilic molecule
FR3045053B1 (fr) * 2015-12-09 2018-01-05 Cisbio Bioassays Agents complexants hydrosolubles a base de triazapyridinophane et complexes de lanthanide fluorescents correspondants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US5068227A (en) * 1989-01-18 1991-11-26 Cyclex, Inc. Cyclodextrins as carriers
WO1991002040A1 (en) * 1989-08-04 1991-02-21 Kosak Kenneth M Cyclodextrin labels for nucleic acid and biochemical analysis
WO1991005605A1 (en) * 1989-10-10 1991-05-02 Kosak Kenneth M Cyclodextrin labels for immunoassay and biochemical analysis
DE69434649T2 (de) * 1993-07-13 2007-02-22 Abbott Laboratories, Abbott Park Durch fluoreszierenden polymer markierte konjugate und zwischenprodukte

Also Published As

Publication number Publication date
ES2187834T3 (es) 2003-06-16
WO1998026287A1 (fr) 1998-06-18
EP0946870A1 (de) 1999-10-06
FR2757162A1 (fr) 1998-06-19
JP3955638B2 (ja) 2007-08-08
EP0946870B1 (de) 2002-11-27
FR2757162B1 (fr) 1999-03-26
JP2001506002A (ja) 2001-05-08
CA2272890C (en) 2004-11-30
ATE228656T1 (de) 2002-12-15
AU5489498A (en) 1998-07-03
CA2272890A1 (en) 1998-06-18
DE69717490D1 (de) 2003-01-09

Similar Documents

Publication Publication Date Title
ATE222254T1 (de) Verwendung von einem metalloporphyrinkonjugat für den nachweis biologischer verbindungen
DE50014571D1 (de) Träger-pharmaka-konjugate
ATE230487T1 (de) Verfahren zur frühen diagnose von carcinomen
WO1999041273A3 (en) Pna and dna conjugates and methods for preparation thereof
BR9812376A (pt) Uso de um pentopiranosil nucleosìdio para a produção de um componente eletronico, e seus conjugados
BR9811039A (pt) Citocina de mamìferos: interleucina-b30 e reagentes relacionados
DE69903391T2 (de) Homogenes, einteiliges Farbentwicklungskonzentrat und Verfahren zu dessen Herstellung
DE69717490D1 (de) Nicht aggregierte fluoreszierende konjugate und verfahren zu ihrer herstellung
DE69716720T2 (de) Verfahren zur cyclotrimerisierung von alkinen in wässrigen lösungen
WO2000035950A3 (en) Reagents and methods useful for detecting diseases of the breast
DE60026354D1 (de) Verfahren zur herstellung von methylcobalamin
DE50007635D1 (de) Verfahren zur diagnose von sjögren-syndrom
AU2001292118A1 (en) Dye-labelled peptide and its diagnostic use
DE69905004D1 (de) Dreidimensionales positioniersystem für endoluminal eingebrachtes material
SI1267937T1 (sl) Polisaharid-polipeptidni konjugat
CA2193082A1 (en) A method for stabilizing hydrolysis-sensitive molecules or molecular moieties
WO1993020852A3 (en) Macrocyclic chelating agents, chelates and conjugates thereof
BR0014019A (pt) Processo para a detecção de formas oxidadas da guanilatociclase e processo para a separação por ativadores da guanilatociclase solúvel com ferro de inibição oxidado
DE29702147U1 (de) Zusammenbau, vor allem für den Fahrzeugbau
IL142680A0 (en) Minimal promoters and uses thereof
WO2001015737A3 (en) Method for coupling molecules
AU2001258614A1 (en) Diagnostic method for alzheimer's disease based on holo-transcobalamin ii
BR9907502A (pt) Misturas de borracha que contêm organossilanopolissulfanos, processo para preparação da mesma, uso da mesma e artigo moldado
DE60108515D1 (de) Verfahren zur herstellung eines pgd2-antagonisten
NL1006080A1 (nl) Verpakkingshouder, plano, alsmede gebruik van een verpakkingshouder.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition