DE69716046D1 - Methode zur erkennung von heparin-induzierter thrombozytopenie - Google Patents

Methode zur erkennung von heparin-induzierter thrombozytopenie

Info

Publication number
DE69716046D1
DE69716046D1 DE69716046T DE69716046T DE69716046D1 DE 69716046 D1 DE69716046 D1 DE 69716046D1 DE 69716046 T DE69716046 T DE 69716046T DE 69716046 T DE69716046 T DE 69716046T DE 69716046 D1 DE69716046 D1 DE 69716046D1
Authority
DE
Germany
Prior art keywords
thrombozytopenia
induced
detecting heparin
heparin
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69716046T
Other languages
English (en)
Other versions
DE69716046T2 (de
Inventor
Manouchehr Moghaddam
Gian Visentin
H Aster
W Boldt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BLOOD CT RES FOUNDATION MILWAU
GENETICS TESTING INST BROOKFIE
Original Assignee
BLOOD CT RES FOUNDATION MILWAU
GENETICS TESTING INST BROOKFIE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BLOOD CT RES FOUNDATION MILWAU, GENETICS TESTING INST BROOKFIE filed Critical BLOOD CT RES FOUNDATION MILWAU
Publication of DE69716046D1 publication Critical patent/DE69716046D1/de
Application granted granted Critical
Publication of DE69716046T2 publication Critical patent/DE69716046T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
DE69716046T 1996-02-28 1997-02-24 Methode zur erkennung von heparin-induzierter thrombozytopenie Expired - Lifetime DE69716046T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1244596P 1996-02-28 1996-02-28
PCT/US1997/002840 WO1997032211A1 (en) 1996-02-28 1997-02-24 Method of detecting heparin-induced thrombocytopenia

Publications (2)

Publication Number Publication Date
DE69716046D1 true DE69716046D1 (de) 2002-11-07
DE69716046T2 DE69716046T2 (de) 2003-06-12

Family

ID=21755010

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69716046T Expired - Lifetime DE69716046T2 (de) 1996-02-28 1997-02-24 Methode zur erkennung von heparin-induzierter thrombozytopenie

Country Status (4)

Country Link
US (1) US5972718A (de)
EP (1) EP0888542B1 (de)
DE (1) DE69716046T2 (de)
WO (1) WO1997032211A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4342560A1 (de) 1993-12-14 1995-06-22 Marbert Gmbh Ectoin und Ectoinderivate als Feuchtigkeitsspender in Kosmetikprodukten
US6210904B1 (en) * 1997-10-14 2001-04-03 Merck & Co., Inc. Anticoagulant test
US20040047828A1 (en) * 1998-08-01 2004-03-11 Merck Patent Gmbh Ectoin or ection derivatives and surfactants
AU7336400A (en) 1999-08-30 2001-03-26 Mustapha Abdelouahed Diagnostic assay for type 2 heparin-induced thrombocytopenia
US7048910B2 (en) 2000-09-07 2006-05-23 Merck Patent Gmbh Use of ectoine or ectoine derivatives for oral care
DE10214257A1 (de) * 2002-03-28 2003-10-16 Merck Patent Gmbh Verwendung von kompatiblen Soluten zur Inhibierung der Freisetzung von Ceramiden
AU2003262738A1 (en) * 2002-08-20 2004-03-11 University Of Massachusetts Assay for thrombocytopenia associated with administration of platelet gpiib-iiia receptor antagonists
JP4580180B2 (ja) * 2004-02-26 2010-11-10 デンカ生研株式会社 免疫測定法用測定値低下抑制剤及びそれを用いた免疫測定法
US20050261241A1 (en) * 2004-05-19 2005-11-24 Celsus Biopharmaceuticals, Inc. Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
US20060172438A1 (en) * 2004-10-04 2006-08-03 David Milunic Methods and kits for detecting heparin/platelet factor 4 antibodies
FR2902884B1 (fr) * 2006-06-23 2008-12-26 Hyphen Biomed Soc Par Actions Procede pour la detection des anticorps heparine-dependants et le diagnostic des pathologies immunes ou auto-immnues potentialisees par l'heparine telle que la thrombopenie induite par l'heparine
EP2265948A4 (de) * 2008-02-29 2011-04-20 Biomedomics Inc Schnelles und empfindliches verfahren zur quantitativen bestimmung des spiegels von durch heparin-pf4-komplex induzierten immunoglobulinantikörpern
JP5618831B2 (ja) * 2008-08-27 2014-11-05 株式会社Ｌｓｉメディエンス 修飾抗ヘパリン／ｐｆ４複合体抗体及びｈｉｔ抗体標準品
US20140038205A1 (en) * 2011-02-18 2014-02-06 Precision Biologic Inc. Methods and compositions relating to coagulation assays
WO2012170435A2 (en) 2011-06-09 2012-12-13 Gen-Probe Incorporated Diagnostic devices, methods and systems for detecting platelet factor 4 (pf4)/heparin antibodies
CN103063592B (zh) * 2012-12-31 2014-05-07 中国医学科学院输血研究所 一种肝素活性的测定方法
US9017958B2 (en) * 2013-03-12 2015-04-28 Bloodcenter Research Foundation, Inc. Method of simultaneous detection of heparin-induced immunoglobulins types G, A, and M
EP3889614A1 (de) 2015-03-03 2021-10-06 Laboratory Corporation of America Holdings Verfahren und systeme zur messung von serotonin in einer probe
CN111534109A (zh) * 2020-05-09 2020-08-14 北京大学第一医院 一种血小板因子4蛋白/聚乙烯磺酸复合物及其制备方法与应用
WO2022081691A1 (en) * 2020-10-14 2022-04-21 Milwaukee Electric Tool Corporation Handheld punch tool

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8200751L (sv) * 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
SE456911B (sv) * 1983-12-19 1988-11-14 Olle Larm Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma
US4717654A (en) * 1984-06-19 1988-01-05 Akzo N.V. Process for solid phase platelet antibody assay
SE466289B (sv) * 1984-09-19 1992-01-27 James Hoffman Makrofagstimulerande komposition jaemte foerfarande foer dess framstaellning
US4743550A (en) * 1985-04-29 1988-05-10 Union Carbide Corporation Method for improving the partition coefficient in enzyme-containing systems having at least two phases
US5049403A (en) * 1989-10-12 1991-09-17 Horsk Hydro A.S. Process for the preparation of surface modified solid substrates
US5213898A (en) * 1989-10-12 1993-05-25 Norsk Hydro A.S. Process for the preparation of surface modified solid substrates
US5466582A (en) * 1990-08-09 1995-11-14 Serbio Thrombocytopenia determination
US5624904A (en) * 1993-11-17 1997-04-29 Massachusetts Institute Of Technology Method for treating gram positive septicemia
US5618917A (en) * 1995-02-15 1997-04-08 Arch Development Corporation Methods and compositions for detecting and treating kidney diseases associated with adhesion of crystals to kidney cells

Also Published As

Publication number Publication date
WO1997032211A1 (en) 1997-09-04
US5972718A (en) 1999-10-26
EP0888542A4 (de) 2000-11-02
EP0888542B1 (de) 2002-10-02
EP0888542A1 (de) 1999-01-07
DE69716046T2 (de) 2003-06-12

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