DE69715668T2 - N-(pyridinylamino)isoindoline und verwandte verbindungen - Google Patents
N-(pyridinylamino)isoindoline und verwandte verbindungenInfo
- Publication number
- DE69715668T2 DE69715668T2 DE69715668T DE69715668T DE69715668T2 DE 69715668 T2 DE69715668 T2 DE 69715668T2 DE 69715668 T DE69715668 T DE 69715668T DE 69715668 T DE69715668 T DE 69715668T DE 69715668 T2 DE69715668 T2 DE 69715668T2
- Authority
- DE
- Germany
- Prior art keywords
- pyridinylamino
- related compounds
- isoindoline
- isoindolines
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
- C07D213/77—Hydrazine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77430896A | 1996-12-27 | 1996-12-27 | |
| US08/959,789 US6004977A (en) | 1996-12-27 | 1997-10-29 | N-(pyridinylamino) isoindolines and related compounds |
| PCT/US1997/020591 WO1998029407A2 (en) | 1996-12-27 | 1997-11-13 | N-(pyridinylamino)isoindolines for treating alzheimer's and depression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69715668D1 DE69715668D1 (de) | 2002-10-24 |
| DE69715668T2 true DE69715668T2 (de) | 2003-07-31 |
Family
ID=27118867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69715668T Expired - Fee Related DE69715668T2 (de) | 1996-12-27 | 1997-11-13 | N-(pyridinylamino)isoindoline und verwandte verbindungen |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0950056B1 (de) |
| JP (1) | JP4256937B2 (de) |
| KR (1) | KR20000062358A (de) |
| AT (1) | ATE224387T1 (de) |
| AU (1) | AU720466B2 (de) |
| BR (1) | BR9714189A (de) |
| CA (1) | CA2276203C (de) |
| DE (1) | DE69715668T2 (de) |
| DK (1) | DK0950056T3 (de) |
| ES (1) | ES2179377T3 (de) |
| HU (1) | HUP0000783A2 (de) |
| IL (1) | IL130642A0 (de) |
| NO (1) | NO993180L (de) |
| PT (1) | PT950056E (de) |
| WO (1) | WO1998029407A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6772195B1 (en) | 1999-10-29 | 2004-08-03 | Electronic Arts, Inc. | Chat clusters for a virtual world application |
| AU2001256733A1 (en) * | 2000-05-16 | 2001-11-26 | Takeda Chemical Industries Ltd. | Melanin-concentrating hormone antagonist |
| KR20060009686A (ko) * | 2004-07-26 | 2006-02-01 | 엘지이노텍 주식회사 | 반도체 발광소자 및 그 제조방법 |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| US9623021B2 (en) | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| KR20160020584A (ko) | 2007-01-22 | 2016-02-23 | 지티엑스, 인코포레이티드 | 핵 수용체에 결합하는 물질 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3852335T2 (de) * | 1987-04-24 | 1995-05-11 | Hoechst Roussel Pharma | N-(Pyridinyl)-1H-indol-1-amine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel. |
| DE69016531T2 (de) * | 1989-08-02 | 1995-07-06 | Hoechst Roussel Pharma | 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. |
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
| US5102891A (en) * | 1990-07-23 | 1992-04-07 | Hoechst-Roussel Pharmaceuticals Inc. | 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates |
| US5328920A (en) * | 1991-04-17 | 1994-07-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted (pyridinylamino)-indoles |
| US5177088A (en) * | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
-
1997
- 1997-11-13 BR BR9714189-5A patent/BR9714189A/pt not_active IP Right Cessation
- 1997-11-13 IL IL13064297A patent/IL130642A0/xx unknown
- 1997-11-13 JP JP52999098A patent/JP4256937B2/ja not_active Expired - Fee Related
- 1997-11-13 PT PT97948250T patent/PT950056E/pt unknown
- 1997-11-13 AT AT97948250T patent/ATE224387T1/de not_active IP Right Cessation
- 1997-11-13 CA CA002276203A patent/CA2276203C/en not_active Expired - Fee Related
- 1997-11-13 EP EP97948250A patent/EP0950056B1/de not_active Expired - Lifetime
- 1997-11-13 DK DK97948250T patent/DK0950056T3/da active
- 1997-11-13 ES ES97948250T patent/ES2179377T3/es not_active Expired - Lifetime
- 1997-11-13 WO PCT/US1997/020591 patent/WO1998029407A2/en active IP Right Grant
- 1997-11-13 AU AU54349/98A patent/AU720466B2/en not_active Ceased
- 1997-11-13 DE DE69715668T patent/DE69715668T2/de not_active Expired - Fee Related
- 1997-11-13 HU HU0000783A patent/HUP0000783A2/hu unknown
- 1997-11-13 KR KR1019997005846A patent/KR20000062358A/ko active IP Right Grant
-
1999
- 1999-06-25 NO NO993180A patent/NO993180L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2276203A1 (en) | 1998-07-09 |
| ES2179377T3 (es) | 2003-01-16 |
| NO993180D0 (no) | 1999-06-25 |
| PT950056E (pt) | 2002-12-31 |
| EP0950056A2 (de) | 1999-10-20 |
| IL130642A0 (en) | 2000-06-01 |
| ATE224387T1 (de) | 2002-10-15 |
| DK0950056T3 (da) | 2003-01-27 |
| CA2276203C (en) | 2003-07-22 |
| NO993180L (no) | 1999-08-26 |
| AU5434998A (en) | 1998-07-31 |
| BR9714189A (pt) | 2000-02-29 |
| WO1998029407A3 (en) | 1998-10-22 |
| JP2001511119A (ja) | 2001-08-07 |
| KR20000062358A (ko) | 2000-10-25 |
| JP4256937B2 (ja) | 2009-04-22 |
| WO1998029407A2 (en) | 1998-07-09 |
| DE69715668D1 (de) | 2002-10-24 |
| HUP0000783A2 (hu) | 2001-04-28 |
| AU720466B2 (en) | 2000-06-01 |
| EP0950056B1 (de) | 2002-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |
|
| 8339 | Ceased/non-payment of the annual fee |