DE69712338D1 - Zusammensetzung auf basis von enalapril und losartan - Google Patents

Zusammensetzung auf basis von enalapril und losartan

Info

Publication number
DE69712338D1
DE69712338D1 DE69712338T DE69712338T DE69712338D1 DE 69712338 D1 DE69712338 D1 DE 69712338D1 DE 69712338 T DE69712338 T DE 69712338T DE 69712338 T DE69712338 T DE 69712338T DE 69712338 D1 DE69712338 D1 DE 69712338D1
Authority
DE
Germany
Prior art keywords
losartan
enalapril
composition based
relates
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69712338T
Other languages
English (en)
Other versions
DE69712338T2 (de
Inventor
H Chen
William Grossman
Bassel Iskandarani
A Kramer
S Sweet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9615182.4A external-priority patent/GB9615182D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69712338D1 publication Critical patent/DE69712338D1/de
Publication of DE69712338T2 publication Critical patent/DE69712338T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69712338T 1996-06-24 1997-06-20 Zusammensetzung auf basis von enalapril und losartan Expired - Fee Related DE69712338T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2030196P 1996-06-24 1996-06-24
GBGB9615182.4A GB9615182D0 (en) 1996-07-19 1996-07-19 A composition of enalapril and losartan
PCT/US1997/010372 WO1997049392A1 (en) 1996-06-24 1997-06-20 A composition of enalapril and losartan

Publications (2)

Publication Number Publication Date
DE69712338D1 true DE69712338D1 (de) 2002-06-06
DE69712338T2 DE69712338T2 (de) 2002-11-07

Family

ID=26309722

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69712338T Expired - Fee Related DE69712338T2 (de) 1996-06-24 1997-06-20 Zusammensetzung auf basis von enalapril und losartan

Country Status (8)

Country Link
EP (1) EP0910375B1 (de)
JP (1) JP2000513356A (de)
AT (1) ATE216881T1 (de)
AU (1) AU724576B2 (de)
CA (1) CA2257946A1 (de)
DE (1) DE69712338T2 (de)
ES (1) ES2175437T3 (de)
WO (1) WO1997049392A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011390A (zh) 1999-01-26 2007-08-08 诺瓦提斯公司 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
GB0020691D0 (en) * 2000-08-22 2000-10-11 Boehringer Ingelheim Pharma Pharmaceutical combination
EP1671632A1 (de) * 2000-08-22 2006-06-21 Boehringer Ingelheim Pharma GmbH & Co. KG Pharmazeutische Kombination von Angiotensin II-Antagonisten und ACE-Hemmern
EP1413315A4 (de) * 2001-08-03 2006-08-16 Takeda Pharmaceutical Medikamente mit verzögerter freisetzung
JP2005508358A (ja) * 2001-10-25 2005-03-31 デポメド・インコーポレイテッド 胃滞留型ロサルタン投与量を用いる治療方法
US20090215756A1 (en) * 2005-05-18 2009-08-27 Combino Pharm, S.L. Formulations containing losartan and/or its salts
EP1908469A1 (de) * 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Angiotensin II Rezeptor Antagonisten zur Behandlung von systemischen Krankheiten bei Katzen
KR101247583B1 (ko) * 2006-12-08 2013-03-26 한미사이언스 주식회사 암로디핀 또는 이의 약제학적 허용가능한 염, 및 로자탄또는 이의 약제학적 허용가능한 염을 함유하는 약제학적조성물
BRPI1013037A2 (pt) 2009-05-20 2019-09-24 Boehringer Ingelheim Ipharmaceuticals Inc "solução farmacêutica oral de telmisartan"

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
DE69124598T2 (de) * 1990-05-11 1997-05-28 Pfizer Synergistische therapeutische zusammensetzungen und verfahren
EP0565634B1 (de) * 1990-12-14 1999-03-17 Smithkline Beecham Corporation Angiotensin-ii-rezeptor blockierende zusammensetzungen
WO1992013521A1 (en) * 1991-01-30 1992-08-20 Alza Corporation Osmotic device for delayed delivery of agent
WO1992019228A1 (en) * 1991-04-29 1992-11-12 Merck & Co., Inc. Optimized tablet formulation
US5492904A (en) * 1991-05-15 1996-02-20 E. I. Du Pont De Nemours And Company Composition of angiotensin-II receptor antagonists and calcium channel blockers
US5160744A (en) * 1991-06-27 1992-11-03 Alza Corporation Verapmil therapy
US5266583A (en) * 1992-09-01 1993-11-30 Merck & Co., Inc. Angitotensin II antagonist
EP0629408A1 (de) * 1993-06-16 1994-12-21 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Kombination von Angiotensin-Converting-Enzyme Hemmern mit A-II-Antagonisten
JP3883205B2 (ja) * 1994-03-29 2007-02-21 メルク エンド カンパニー インコーポレーテッド アンギオテンシン▲ｉｉ▼レセプタ遮断イミダゾールによるアテローム性動脈硬化症の治療

Also Published As

Publication number Publication date
DE69712338T2 (de) 2002-11-07
EP0910375A1 (de) 1999-04-28
AU724576B2 (en) 2000-09-28
ATE216881T1 (de) 2002-05-15
ES2175437T3 (es) 2002-11-16
EP0910375A4 (de) 1999-09-01
WO1997049392A1 (en) 1997-12-31
EP0910375B1 (de) 2002-05-02
JP2000513356A (ja) 2000-10-10
AU3571097A (en) 1998-01-14
CA2257946A1 (en) 1997-12-31

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee