DE69705376D1 - Aminomethylheterozyclischederivate, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen - Google Patents

Aminomethylheterozyclischederivate, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Info

Publication number
DE69705376D1
DE69705376D1 DE69705376T DE69705376T DE69705376D1 DE 69705376 D1 DE69705376 D1 DE 69705376D1 DE 69705376 T DE69705376 T DE 69705376T DE 69705376 T DE69705376 T DE 69705376T DE 69705376 D1 DE69705376 D1 DE 69705376D1
Authority
DE
Germany
Prior art keywords
processes
preparation
heterocyclic derivatives
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69705376T
Other languages
English (en)
Other versions
DE69705376T2 (de
Inventor
Daniel Lesieur
Pascal Carato
Jean-Paul Bonte
Patrick Depreux
Daniel-Henri Caignard
Mark Millan
Adrian Newman-Tancredi
Pierre Renard
Marie-Claire Rettori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of DE69705376D1 publication Critical patent/DE69705376D1/de
Publication of DE69705376T2 publication Critical patent/DE69705376T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE69705376T 1996-11-08 1997-11-06 Aminomethylheterozyclischederivate, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen Expired - Fee Related DE69705376T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9613652A FR2755690B1 (fr) 1996-11-08 1996-11-08 Nouveaux derives aminomethyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
DE69705376D1 true DE69705376D1 (de) 2001-08-02
DE69705376T2 DE69705376T2 (de) 2002-02-14

Family

ID=9497457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69705376T Expired - Fee Related DE69705376T2 (de) 1996-11-08 1997-11-06 Aminomethylheterozyclischederivate, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Country Status (20)

Country Link
US (1) US5919784A (de)
EP (1) EP0841330B1 (de)
JP (1) JPH10139780A (de)
CN (1) CN1072655C (de)
AT (1) ATE202564T1 (de)
AU (1) AU726681B2 (de)
BR (1) BR9705456A (de)
CA (1) CA2220996A1 (de)
DE (1) DE69705376T2 (de)
DK (1) DK0841330T3 (de)
ES (1) ES2160308T3 (de)
FR (1) FR2755690B1 (de)
GR (1) GR3036472T3 (de)
HK (1) HK1010869A1 (de)
HU (1) HUP9701921A3 (de)
NO (1) NO309477B1 (de)
NZ (1) NZ329133A (de)
PL (1) PL323032A1 (de)
PT (1) PT841330E (de)
ZA (1) ZA9710055B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177422B1 (en) * 1996-05-29 2001-01-23 Warner-Lambert Company Benzoxazinone dopamine D4 receptor antagonists
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20040192669A1 (en) 2000-04-13 2004-09-30 Rosenfeld Mark J. Novel compounds for use in weight loss and appetite suppression in humans
US7794761B2 (en) * 2000-04-13 2010-09-14 Seroctin Research & Technology, Inc. Methods for inducing anti-anxiety and calming effects in animals and humans
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
AR047759A1 (es) * 2003-09-26 2006-02-22 Vertex Pharma Derivados de fenil - piperazina como moduladores de receptores muscarnicos
US7524877B2 (en) 2003-11-20 2009-04-28 Seroctin Research & Technology, Inc. Compounds for use in weight loss and appetite suppression in humans
EP2400968B1 (de) * 2009-02-26 2016-09-28 Reviva Pharmaceuticals, Inc. Zusammensetzungen, ihre synthese und verfahren zur verwendung von arylpiperazinderivaten
EP2563143A4 (de) * 2010-04-29 2013-09-25 Merck Sharp & Dohme Substituierte 1,3-benzothiazol-2(3h)-one und [1,3-]thiazolo-[5,4-b-]pyridin-2(-1h)-one als positive allostere modulatoren von mglur2
WO2017070796A1 (en) * 2015-10-30 2017-05-04 Trillium Therapeutics Inc. Heterocycle derivatives and their use for the treatment of cns disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
FR2637286A1 (fr) * 1988-10-04 1990-04-06 Adir Nouveaux derives benzoxazolinoniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5234924A (en) * 1990-09-26 1993-08-10 Adir Et Compagnie Benzothiazine and benzothiazole compounds useful as analgesics
DE4037427A1 (de) * 1990-11-24 1992-05-27 Kali Chemie Pharma Gmbh Heterocyclisch substituierte piperazinoalkylbenzoxazin und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2702214B1 (fr) * 1993-03-05 1995-04-14 Adir Nouveaux composés (aryl(alkyl)carbonyl)-hétérocycliques, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
FR2717810B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
CA2145027A1 (fr) * 1994-03-22 1995-09-23 Les Laboratoires Servier Aminoalkyl benzothiazolinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HK1010869A1 (en) 1999-07-02
HUP9701921A3 (en) 1999-03-29
ATE202564T1 (de) 2001-07-15
JPH10139780A (ja) 1998-05-26
FR2755690B1 (fr) 1998-12-18
GR3036472T3 (en) 2001-11-30
ES2160308T3 (es) 2001-11-01
DK0841330T3 (da) 2001-09-03
BR9705456A (pt) 2000-02-08
CA2220996A1 (fr) 1998-05-08
DE69705376T2 (de) 2002-02-14
NO309477B1 (no) 2001-02-05
CN1182083A (zh) 1998-05-20
AU4440397A (en) 1998-05-14
NO975121D0 (no) 1997-11-07
US5919784A (en) 1999-07-06
EP0841330A1 (de) 1998-05-13
ZA9710055B (en) 1998-05-25
FR2755690A1 (fr) 1998-05-15
PL323032A1 (en) 1998-05-11
HU9701921D0 (en) 1998-01-28
HUP9701921A2 (hu) 1998-12-28
PT841330E (pt) 2001-10-30
NO975121L (no) 1998-05-11
CN1072655C (zh) 2001-10-10
EP0841330B1 (de) 2001-06-27
NZ329133A (en) 1998-08-26
AU726681B2 (en) 2000-11-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LES LABORATOIRES SERVIER, NEUILLY SUR SEINE, FR

8339 Ceased/non-payment of the annual fee