DE69704778D1 - Verfahren zur herstellung von salzen von erythromicyn, roxithromicyn, clarythromicyn und azithromycin - Google Patents

Verfahren zur herstellung von salzen von erythromicyn, roxithromicyn, clarythromicyn und azithromycin

Info

Publication number
DE69704778D1
DE69704778D1 DE69704778T DE69704778T DE69704778D1 DE 69704778 D1 DE69704778 D1 DE 69704778D1 DE 69704778 T DE69704778 T DE 69704778T DE 69704778 T DE69704778 T DE 69704778T DE 69704778 D1 DE69704778 D1 DE 69704778D1
Authority
DE
Germany
Prior art keywords
erythromycin
azithromycin
under nitrogen
roxithromicyn
erythromicyn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69704778T
Other languages
English (en)
Other versions
DE69704778T2 (de
Inventor
Helmut Schickaneder
Aggelos Nikolopoulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Russinsky Ltd
Original Assignee
Russinsky Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Russinsky Ltd filed Critical Russinsky Ltd
Publication of DE69704778D1 publication Critical patent/DE69704778D1/de
Application granted granted Critical
Publication of DE69704778T2 publication Critical patent/DE69704778T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69704778T 1996-08-07 1997-08-07 Verfahren zur herstellung von salzen von erythromicyn, roxithromicyn, clarythromicyn und azithromycin Expired - Fee Related DE69704778T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE960568 1996-08-07
PCT/IE1997/000056 WO1998005674A1 (en) 1996-08-07 1997-08-07 Process for the production of salts of erythromycin, roxithromycin, clarithromycin and azithromycin

Publications (2)

Publication Number Publication Date
DE69704778D1 true DE69704778D1 (de) 2001-06-13
DE69704778T2 DE69704778T2 (de) 2001-09-20

Family

ID=11041234

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69704778T Expired - Fee Related DE69704778T2 (de) 1996-08-07 1997-08-07 Verfahren zur herstellung von salzen von erythromicyn, roxithromicyn, clarythromicyn und azithromycin

Country Status (7)

Country Link
EP (1) EP0922051B1 (de)
AT (1) ATE201026T1 (de)
AU (1) AU3861497A (de)
CA (1) CA2255124A1 (de)
DE (1) DE69704778T2 (de)
IE (1) IE970584A1 (de)
WO (1) WO1998005674A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1121134B1 (de) * 1998-10-20 2004-03-03 Russinsky Limited Derivate des erythromycins, des clarithromycins, des roxithromycins oder des azithromycin mit antibiotischer und mucolytischer wirkung
EP2513130B1 (de) * 2009-12-18 2016-05-25 North-West University Zusammensetzung mit einer amorphen nichtkristallinen roxithromycin-glasform
CN103232506B (zh) * 2013-04-11 2016-02-03 宜昌东阳光药业股份有限公司 克拉霉素杂质o及其相类似化合物的制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502627A1 (fr) * 1981-02-02 1982-10-01 Refarmed Sa Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent
IT1189285B (it) * 1982-05-28 1988-02-04 Nuovo Consor Sanitar Nazionale Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante
IT1190987B (it) * 1982-09-07 1988-02-24 Pharma Edmond Srl Tioesteri dell'acido acetilsalicilico,procedimento per la loro preparazione e composizioni farmaceutiche che li conttengono
IT1173441B (it) * 1984-03-14 1987-06-24 Edmond Pharma Srl Sali di eritromicina con derivati dell'acido acetico,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
GB8521402D0 (en) * 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
AU4399396A (en) * 1994-12-19 1996-07-10 Russinsky Limited Compounds

Also Published As

Publication number Publication date
EP0922051A1 (de) 1999-06-16
EP0922051B1 (de) 2001-05-09
IE970584A1 (en) 2000-02-09
CA2255124A1 (en) 1998-02-12
AU3861497A (en) 1998-02-25
ATE201026T1 (de) 2001-05-15
DE69704778T2 (de) 2001-09-20
WO1998005674A1 (en) 1998-02-12

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee