DE69701840T2 - Verfahren zur asymmetrischen synthese von s-acylierten derivaten von 2-mercaptomethyl-3-phenylpropionsäure und deren verwendung zur synthese von n-mercaptoacyl aminosäure-derivaten - Google Patents

Verfahren zur asymmetrischen synthese von s-acylierten derivaten von 2-mercaptomethyl-3-phenylpropionsäure und deren verwendung zur synthese von n-mercaptoacyl aminosäure-derivaten

Info

Publication number
DE69701840T2
DE69701840T2 DE69701840T DE69701840T DE69701840T2 DE 69701840 T2 DE69701840 T2 DE 69701840T2 DE 69701840 T DE69701840 T DE 69701840T DE 69701840 T DE69701840 T DE 69701840T DE 69701840 T2 DE69701840 T2 DE 69701840T2
Authority
DE
Germany
Prior art keywords
synthesis
derivatives
pct
mercaptomethyl
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69701840T
Other languages
English (en)
Other versions
DE69701840D1 (de
Inventor
Denis Danvy
Thierry Monteil
Pierre Duhamel
Lucette Duhamel
Jeanne-Marie Lecomte
Jean-Charles Schwartz
Nadine Noel-Lefebrvre
Claude Gros
Jean-Christophe Plaquevent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioprojet SC
Original Assignee
Bioprojet SC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet SC filed Critical Bioprojet SC
Publication of DE69701840D1 publication Critical patent/DE69701840D1/de
Application granted granted Critical
Publication of DE69701840T2 publication Critical patent/DE69701840T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69701840T 1996-02-05 1997-02-04 Verfahren zur asymmetrischen synthese von s-acylierten derivaten von 2-mercaptomethyl-3-phenylpropionsäure und deren verwendung zur synthese von n-mercaptoacyl aminosäure-derivaten Expired - Lifetime DE69701840T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9601360A FR2744446B1 (fr) 1996-02-05 1996-02-05 Procede de synthese asymetrique des derives s-acyles de l'acide 2-mercaptomethyl 3-phenyl propanoique, application a la synthese de derives n-(mercaptoacyl) amino-acides
PCT/FR1997/000218 WO1997029086A1 (fr) 1996-02-05 1997-02-04 Procede de synthese asymetrique des derives s-acyles de l'acide 2-mercaptomethyl 3-phenyl propanoique, application a la synthese de derives n-(mercaptoacyl) amino-acides

Publications (2)

Publication Number Publication Date
DE69701840D1 DE69701840D1 (de) 2000-06-08
DE69701840T2 true DE69701840T2 (de) 2000-10-12

Family

ID=9488842

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69701840T Expired - Lifetime DE69701840T2 (de) 1996-02-05 1997-02-04 Verfahren zur asymmetrischen synthese von s-acylierten derivaten von 2-mercaptomethyl-3-phenylpropionsäure und deren verwendung zur synthese von n-mercaptoacyl aminosäure-derivaten

Country Status (11)

Country Link
US (1) US6013829A (de)
EP (1) EP0820439B1 (de)
JP (1) JP4560147B2 (de)
AT (1) ATE192433T1 (de)
DE (1) DE69701840T2 (de)
DK (1) DK0820439T3 (de)
ES (1) ES2146981T3 (de)
FR (1) FR2744446B1 (de)
GR (1) GR3033843T3 (de)
PT (1) PT820439E (de)
WO (1) WO1997029086A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106363A (ja) * 1997-10-03 1999-04-20 Ajinomoto Co Inc 光学活性２−ヒドロキシメチル−３−フェニルプロピオン酸の製造方法
FR2772027B1 (fr) * 1997-12-10 2000-02-04 Fournier Ind & Sante Procede de preparation asymetrique de derives de l'acide 2-mercaptomethyl-3-phenyl-propanoique, utilisation pour synthese de principes actifs chiraux
EP0937710B1 (de) * 1998-02-16 2003-04-16 Ajinomoto Co., Inc. Verfahren zur Herstellung von optisch aktiven Phenylpropionsäure-Derivat
WO2004060885A1 (ja) * 2002-12-27 2004-07-22 Kaneka Corporation 光学活性２−チオメチル−３−フェニルプロピオン酸誘導体およびその合成中間体の製造法
CN101768095A (zh) * 2008-12-26 2010-07-07 山东齐都药业有限公司 一种消旋卡多曲的制备方法
WO2013098826A1 (en) * 2011-12-26 2013-07-04 Symed Labs Limited "a process for the preparation of n-[2-[(acetylthio) methyl]-1-oxo-3-phenylpropyl] glycine phenyl methyl ester and intermediates thereof"
CN109438303B (zh) * 2018-11-13 2020-10-16 山东齐都药业有限公司 一锅法制备消旋卡多曲的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR501870A (fr) * 1919-06-24 1920-04-28 Knut Eenberg Nouvel alliage et son procédé d'obtention
EP0136883B1 (de) * 1983-10-03 1987-11-25 E.R. Squibb & Sons, Inc. Enkephalinase Inhibitoren
FR2623498B1 (fr) * 1987-11-24 1990-04-06 Bioprojet Soc Civ Nouveaux composes enantiomeres derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques
CA2004846A1 (en) * 1988-12-19 1990-06-19 Yutaka Koike N-substituted acylamino acid compounds, process for their production and their use
FR2673105B1 (fr) * 1991-02-26 1995-01-13 Bioprojet Soc Civ Nouvelles compositions pharmaceutiques, notamment pour le traitement des colopathies fonctionnelles, et procedes de preparation de compositions et de medicaments, notamment pour le traitement de ces affections.

Also Published As

Publication number Publication date
ATE192433T1 (de) 2000-05-15
US6013829A (en) 2000-01-11
DE69701840D1 (de) 2000-06-08
DK0820439T3 (da) 2000-08-07
EP0820439B1 (de) 2000-05-03
FR2744446A1 (fr) 1997-08-08
WO1997029086A1 (fr) 1997-08-14
JP4560147B2 (ja) 2010-10-13
GR3033843T3 (en) 2000-10-31
FR2744446B1 (fr) 1998-04-17
PT820439E (pt) 2000-10-31
ES2146981T3 (es) 2000-08-16
JPH11503470A (ja) 1999-03-26
EP0820439A1 (de) 1998-01-28

Similar Documents

Publication Publication Date Title
DE19681532T1 (de) Verfahren zur Herstellung von L-Glutaminsäure durch Fermentation
HUT70587A (en) Unsaturated aliphatic dicarboxylic acids, compositions containing such dicarboxylic acids, mathods for production of such dicarboxylic acids and compositions and for pharmaceutical and cosmetical using
DE69412109D1 (de) Salzetersaüreester mit entzündungshemmender und/oder schmerzlindernder wirkung und verfahren zu deren herstellung
EP0684040A3 (de) Hautbehandlungsmittel
DE59303365D1 (de) Derivate in der vitamin d-reihe mit modifikationen in der 20 position, verfahren zu ihrer herstellung, zwischenprodukte für dieses verfahren, diese derivate enthaltende pharmazeutische präparate sowie deren verwendung zur herstellung von arzneimitteln
DE69530306T2 (de) Verfahren zur herstellung von l-lysin und l-glutaminsäure durch fermentation
ATE135712T1 (de) Polypeptid, dessen verfahren zur herstellung und dieses enthaltende pharmazeutische zusammensetzung und deren benutzung
ATE264392T1 (de) Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salze
DE69701840T2 (de) Verfahren zur asymmetrischen synthese von s-acylierten derivaten von 2-mercaptomethyl-3-phenylpropionsäure und deren verwendung zur synthese von n-mercaptoacyl aminosäure-derivaten
DE69616638T2 (de) Verfahren zur Herstellung von Bänder aus nichtrostendem Stahl
DE69503761D1 (de) Verfahren zur herstellung von gamma-butyrolacton
ATE154393T1 (de) Verfahren zur herstellung von trans-l-hydroxy- prolin
AU2534595A (en) Angiotensin ii for improving fertilization
DE3575743D1 (de) Verfahren zur gewinnung von phenylalanin-dehydrogenase enthaltenden mikroorganismen und deren verwendung zur herstellung von l-alpha-aminosaeuren.
DE59000702D1 (de) Verfahren zur fermentativen herstellung von 2-(4-hydroxiphenoxi-)propionsaeure.
ATA262593A (de) Verfahren zur herstellung von n-substituierten glycinestern und verfahren zur indigosynthese aus den so hergestellten glycinestern
DE59709792D1 (de) Ringannelierte dihydropyrane, verfahren zur herstellung sowie deren verwendung
ATE170565T1 (de) Verfahren zur biotechnologischen herstellung von alkoholen, aldehyden und carbonsäuren
ATE137736T1 (de) Verfahren zur herstellung von einem optisch reinen aminoalkohol
DE59309261D1 (de) Verfahren zur stereoselektiven synthese von 3-substituierten 2-thiomethylpropionsäuren
ATE183737T1 (de) Verfahren zur stereoselektiven synthese von 3- substituierten 2-sulfonylmethylpropionsäuren sowie zwischenprodukte
ATE155788T1 (de) Verfahren zur herstellung von rufloxacin und salze davon
ATE200776T1 (de) Verfahren zur herstellung von 2,4,5-tribrompyrrol-3-carbonitril
ATE312074T1 (de) Synthese von alpha-amino-alpha',alpha'- dihaloketonen und verfahren zur herstellung von beta)-aminosäurederivaten durch verwendung derselben
ATE292189T1 (de) Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition