GR3033843T3 - Method for the asymmetrical synthesis of s-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid, and use thereof for synthesising n-(mercaptoacyl) amino acid derivatives - Google Patents

Method for the asymmetrical synthesis of s-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid, and use thereof for synthesising n-(mercaptoacyl) amino acid derivatives

Info

Publication number
GR3033843T3
GR3033843T3 GR20000401544T GR20000401544T GR3033843T3 GR 3033843 T3 GR3033843 T3 GR 3033843T3 GR 20000401544 T GR20000401544 T GR 20000401544T GR 20000401544 T GR20000401544 T GR 20000401544T GR 3033843 T3 GR3033843 T3 GR 3033843T3
Authority
GR
Greece
Prior art keywords
derivatives
pct
mercaptoacyl
mercaptomethyl
amino acid
Prior art date
Application number
GR20000401544T
Other languages
English (en)
Inventor
Denis Danvy
Thierry Monteil
Pierre Duhamel
Lucette Duhamel
Jeanne-Marie Lecomte
Jean-Charles Schwartz
Nadine Noel-Lefebrvre
Claude Gros
Jean-Christophe Plaquevent
Original Assignee
Ile Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile Bioprojet Soc Civ filed Critical Ile Bioprojet Soc Civ
Publication of GR3033843T3 publication Critical patent/GR3033843T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GR20000401544T 1996-02-05 2000-06-30 Method for the asymmetrical synthesis of s-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid, and use thereof for synthesising n-(mercaptoacyl) amino acid derivatives GR3033843T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9601360A FR2744446B1 (fr) 1996-02-05 1996-02-05 Procede de synthese asymetrique des derives s-acyles de l'acide 2-mercaptomethyl 3-phenyl propanoique, application a la synthese de derives n-(mercaptoacyl) amino-acides
PCT/FR1997/000218 WO1997029086A1 (fr) 1996-02-05 1997-02-04 Procede de synthese asymetrique des derives s-acyles de l'acide 2-mercaptomethyl 3-phenyl propanoique, application a la synthese de derives n-(mercaptoacyl) amino-acides

Publications (1)

Publication Number Publication Date
GR3033843T3 true GR3033843T3 (en) 2000-10-31

Family

ID=9488842

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000401544T GR3033843T3 (en) 1996-02-05 2000-06-30 Method for the asymmetrical synthesis of s-acylated derivatives of 2-mercaptomethyl 3-phenyl propanoic acid, and use thereof for synthesising n-(mercaptoacyl) amino acid derivatives

Country Status (11)

Country Link
US (1) US6013829A (el)
EP (1) EP0820439B1 (el)
JP (1) JP4560147B2 (el)
AT (1) ATE192433T1 (el)
DE (1) DE69701840T2 (el)
DK (1) DK0820439T3 (el)
ES (1) ES2146981T3 (el)
FR (1) FR2744446B1 (el)
GR (1) GR3033843T3 (el)
PT (1) PT820439E (el)
WO (1) WO1997029086A1 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106363A (ja) * 1997-10-03 1999-04-20 Ajinomoto Co Inc 光学活性２−ヒドロキシメチル−３−フェニルプロピオン酸の製造方法
FR2772027B1 (fr) * 1997-12-10 2000-02-04 Fournier Ind & Sante Procede de preparation asymetrique de derives de l'acide 2-mercaptomethyl-3-phenyl-propanoique, utilisation pour synthese de principes actifs chiraux
EP0937710B1 (en) * 1998-02-16 2003-04-16 Ajinomoto Co., Inc. Method for producing an optically active phenylpropionic acid derivative
US20060089503A1 (en) * 2002-12-27 2006-04-27 Kaneka Corporation Processes for producing optically active 2-thiomethyl-3-phenylpropionic acid derivative and for producing intermediate therefor
CN101768095A (zh) * 2008-12-26 2010-07-07 山东齐都药业有限公司 一种消旋卡多曲的制备方法
WO2013098826A1 (en) * 2011-12-26 2013-07-04 Symed Labs Limited "a process for the preparation of n-[2-[(acetylthio) methyl]-1-oxo-3-phenylpropyl] glycine phenyl methyl ester and intermediates thereof"
CN109438303B (zh) * 2018-11-13 2020-10-16 山东齐都药业有限公司 一锅法制备消旋卡多曲的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR501870A (fr) * 1919-06-24 1920-04-28 Knut Eenberg Nouvel alliage et son procédé d'obtention
EP0136883B1 (en) * 1983-10-03 1987-11-25 E.R. Squibb & Sons, Inc. Enkephalinase inhibitors
FR2623498B1 (fr) * 1987-11-24 1990-04-06 Bioprojet Soc Civ Nouveaux composes enantiomeres derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques
CA2004846A1 (en) * 1988-12-19 1990-06-19 Yutaka Koike N-substituted acylamino acid compounds, process for their production and their use
FR2673105B1 (fr) * 1991-02-26 1995-01-13 Bioprojet Soc Civ Nouvelles compositions pharmaceutiques, notamment pour le traitement des colopathies fonctionnelles, et procedes de preparation de compositions et de medicaments, notamment pour le traitement de ces affections.

Also Published As

Publication number Publication date
WO1997029086A1 (fr) 1997-08-14
ES2146981T3 (es) 2000-08-16
JPH11503470A (ja) 1999-03-26
DE69701840T2 (de) 2000-10-12
FR2744446A1 (fr) 1997-08-08
JP4560147B2 (ja) 2010-10-13
FR2744446B1 (fr) 1998-04-17
US6013829A (en) 2000-01-11
PT820439E (pt) 2000-10-31
EP0820439A1 (fr) 1998-01-28
DK0820439T3 (da) 2000-08-07
EP0820439B1 (fr) 2000-05-03
ATE192433T1 (de) 2000-05-15
DE69701840D1 (de) 2000-06-08

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