DE69637676D1 - Verwendung von lokal verabreichten Lysine zur VERBESSERUNG DER VASKULAREN FUNKTION - Google Patents
Verwendung von lokal verabreichten Lysine zur VERBESSERUNG DER VASKULAREN FUNKTIONInfo
- Publication number
- DE69637676D1 DE69637676D1 DE69637676T DE69637676T DE69637676D1 DE 69637676 D1 DE69637676 D1 DE 69637676D1 DE 69637676 T DE69637676 T DE 69637676T DE 69637676 T DE69637676 T DE 69637676T DE 69637676 D1 DE69637676 D1 DE 69637676D1
- Authority
- DE
- Germany
- Prior art keywords
- lysines
- locally administered
- vascular function
- improve vascular
- improve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 235000018977 lysine Nutrition 0.000 title 1
- 150000002669 lysines Chemical class 0.000 title 1
- 230000004218 vascular function Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/556,035 US5891459A (en) | 1993-06-11 | 1995-11-09 | Enhancement of vascular function by modulation of endogenous nitric oxide production or activity |
US08/695,792 US5852058A (en) | 1993-06-11 | 1996-08-12 | Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury |
PCT/US1996/017241 WO1997016983A1 (en) | 1995-11-09 | 1996-10-24 | Enhancement of vascular function by modulation of endogenous nitric oxide production or activity |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69637676D1 true DE69637676D1 (de) | 2008-10-23 |
Family
ID=24794481
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69637676T Expired - Fee Related DE69637676D1 (de) | 1995-11-09 | 1996-10-24 | Verwendung von lokal verabreichten Lysine zur VERBESSERUNG DER VASKULAREN FUNKTION |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1003500A4 (de) |
JP (1) | JP2000516612A (de) |
DE (1) | DE69637676D1 (de) |
WO (1) | WO1998006389A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6587718B2 (en) | 1999-10-08 | 2003-07-01 | Scimed Life Systems, Inc. | Iontophoretic delivery to heart tissue |
US6706274B2 (en) | 2001-01-18 | 2004-03-16 | Scimed Life Systems, Inc. | Differential delivery of nitric oxide |
US8506617B1 (en) | 2002-06-21 | 2013-08-13 | Advanced Cardiovascular Systems, Inc. | Micronized peptide coated stent |
EP3556401A1 (de) | 2005-05-27 | 2019-10-23 | The University of North Carolina at Chapel Hill | Stickoxidfreisetzende partikel für stickoxidtherapeutika und biomedizinische anwendungen |
ES2958410T3 (es) | 2009-08-21 | 2024-02-08 | Novan Inc | Geles tópicos |
EP2467173B8 (de) | 2009-08-21 | 2019-06-19 | Novan, Inc. | Wundverbände, verfahren zu ihrer anwendung und verfahren zu ihrer herstellung |
US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
WO2012118829A2 (en) | 2011-02-28 | 2012-09-07 | Novan, Inc. | Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236413B1 (en) * | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
US5499971A (en) * | 1990-06-15 | 1996-03-19 | Cortrak Medical, Inc. | Method for iontophoretically delivering drug adjacent to a heart |
US5498238A (en) * | 1990-06-15 | 1996-03-12 | Cortrak Medical, Inc. | Simultaneous angioplasty and phoretic drug delivery |
AU655780B2 (en) * | 1990-10-30 | 1995-01-12 | Clintec Nutrition Company | A method and composition for the protection of a metabolic recovery of ischemic cardiac tissue |
US5171217A (en) * | 1991-02-28 | 1992-12-15 | Indiana University Foundation | Method for delivery of smooth muscle cell inhibitors |
US5428070A (en) * | 1993-06-11 | 1995-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production of activity |
US5852058A (en) * | 1993-06-11 | 1998-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury |
US5482925A (en) * | 1994-03-17 | 1996-01-09 | Comedicus Incorporated | Complexes of nitric oxide with cardiovascular amines as dual acting cardiovascular agents |
US5681278A (en) * | 1994-06-23 | 1997-10-28 | Cormedics Corp. | Coronary vasculature treatment method |
-
1996
- 1996-10-24 DE DE69637676T patent/DE69637676D1/de not_active Expired - Fee Related
-
1997
- 1997-08-07 WO PCT/US1997/013905 patent/WO1998006389A1/en active Application Filing
- 1997-08-07 EP EP97938163A patent/EP1003500A4/de not_active Withdrawn
- 1997-08-07 JP JP10509860A patent/JP2000516612A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1003500A1 (de) | 2000-05-31 |
WO1998006389A1 (en) | 1998-02-19 |
EP1003500A4 (de) | 2004-06-23 |
JP2000516612A (ja) | 2000-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |