DE69636546D1 - Natürliche oder synthetische retroelement-sequenzen, die die insertion von nukleotiden in eukaryotische zellen erlauben - Google Patents

Natürliche oder synthetische retroelement-sequenzen, die die insertion von nukleotiden in eukaryotische zellen erlauben

Info

Publication number
DE69636546D1
DE69636546D1 DE69636546T DE69636546T DE69636546D1 DE 69636546 D1 DE69636546 D1 DE 69636546D1 DE 69636546 T DE69636546 T DE 69636546T DE 69636546 T DE69636546 T DE 69636546T DE 69636546 D1 DE69636546 D1 DE 69636546D1
Authority
DE
Germany
Prior art keywords
synthetic
natural
allocating
nucleotides
eukaryotic cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69636546T
Other languages
English (en)
Other versions
DE69636546T2 (de
Inventor
Andre Choulika
Jean-Francois Nicolas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of DE69636546D1 publication Critical patent/DE69636546D1/de
Application granted granted Critical
Publication of DE69636546T2 publication Critical patent/DE69636546T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69636546T 1995-08-07 1996-07-25 Natürliche oder synthetische retroelement-sequenzen, die die insertion von nukleotiden in eukaryotische zellen erlauben Expired - Lifetime DE69636546T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9509587A FR2737731B1 (fr) 1995-08-07 1995-08-07 Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote
FR9509587 1995-08-07
PCT/FR1996/001178 WO1997006271A1 (fr) 1995-08-07 1996-07-25 Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote

Publications (2)

Publication Number Publication Date
DE69636546D1 true DE69636546D1 (de) 2006-10-26
DE69636546T2 DE69636546T2 (de) 2007-08-02

Family

ID=9481767

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69636546T Expired - Lifetime DE69636546T2 (de) 1995-08-07 1996-07-25 Natürliche oder synthetische retroelement-sequenzen, die die insertion von nukleotiden in eukaryotische zellen erlauben
DE69638235T Expired - Lifetime DE69638235D1 (de) 1995-08-07 1996-07-25 Sequenzen von natürlischen oder synthetischen Retroelementen, die die Insertion von nukleotiden Sequenzen in eukaryotische Zellen erlauben

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69638235T Expired - Lifetime DE69638235D1 (de) 1995-08-07 1996-07-25 Sequenzen von natürlischen oder synthetischen Retroelementen, die die Insertion von nukleotiden Sequenzen in eukaryotische Zellen erlauben

Country Status (12)

Country Link
US (2) US6200800B1 (de)
EP (2) EP0843732B1 (de)
JP (2) JP4173543B2 (de)
AT (2) ATE339511T1 (de)
CA (1) CA2226301C (de)
DE (2) DE69636546T2 (de)
DK (1) DK0843732T3 (de)
ES (1) ES2276407T3 (de)
FR (1) FR2737731B1 (de)
HK (1) HK1105662A1 (de)
PT (1) PT843732E (de)
WO (1) WO1997006271A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2737731B1 (fr) * 1995-08-07 1997-10-10 Pasteur Institut Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote
US6534314B1 (en) 1996-06-14 2003-03-18 Massachusetts Institute Of Technology Methods and compositions for transforming cells
US5928914A (en) * 1996-06-14 1999-07-27 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Methods and compositions for transforming cells
US6410317B1 (en) * 1999-07-14 2002-06-25 Clontech Laboratories, Inc. Recombinase-based methods for producing expression vectors and compositions for use in practicing the same
GB2355459B (en) * 1999-11-29 2001-09-26 Isis Innovation A dominant conditional lethal genetic system
EP1274854B1 (de) * 2000-04-12 2009-04-08 Dana-Farber Cancer Institute Selbstlöschende rekombinasen, dafür kodierende nukleinsäuren und verfahren zu deren verwendung
US20040231006A1 (en) * 2000-04-12 2004-11-18 Silver Daniel P. Self-extinguishing recombinases, nucleic acids encoding them and methods of using the same
AU2001263160A1 (en) 2000-05-19 2001-12-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Utilization of non-viral sequences for minus-strand dna transfer and gene reconstitution
GB2402675B (en) * 2003-05-12 2008-02-20 Oxitec Ltd Resistance dilution
GB2403475B (en) * 2003-07-01 2008-02-06 Oxitec Ltd Stable integrands
GB2404382B (en) * 2003-07-28 2008-01-30 Oxitec Ltd Pest control
EP2392657B1 (de) * 2005-07-05 2013-09-25 The Chemo-Sero-Therapeutic Research Institute Modifizierter Transposonvektor und seine Verwendung
GB2443186A (en) 2006-10-25 2008-04-30 Oxitec Ltd Expression system for mediating alternative splicing
GB2500113A (en) 2012-03-05 2013-09-11 Oxitec Ltd Arthropod male germline gene expression system
GB201303932D0 (en) 2013-03-05 2013-04-17 Oxitec Ltd Muscle actin promoter
GB2526867A (en) 2014-06-05 2015-12-09 Oxitec Ltd Gene expression system
WO2018029534A1 (en) 2016-08-12 2018-02-15 Oxitec Ltd. A self-limiting, sex-specific gene and methods of using

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61502885A (ja) 1984-08-06 1986-12-11 ヒル．ロバ−ト ロツク式チユ−ブ巻取り装置
US5219740A (en) * 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
ATE83008T1 (de) * 1987-07-21 1992-12-15 Du Pont Merck Pharma Verfahren fuer die herstellung von in tierischen zellen stabilen und lebensfaehigen rekombinanten viralen vektoren.
FR2629469B1 (fr) * 1988-03-31 1990-12-21 Pasteur Institut Retrovirus recombinant defectif, son application a l'integration de sequences codantes pour des proteines determinees dans le genome de cultures cellulaires infectables par le retrovirus sauvage correspondant et adns recombinants pour la production de ce retrovirus recombinant
US5658775A (en) * 1988-05-17 1997-08-19 Sloan-Kettering Institute For Cancer Research Double copy retroviral vector
JP3249516B2 (ja) * 1990-10-31 2002-01-21 ソマティクス セラピー コーポレイション 遺伝子治療のためのレトロウイルスのベクター
US5629159A (en) * 1995-06-07 1997-05-13 California Institute Of Technology Immortalization and disimmortalization of cells
FR2737731B1 (fr) * 1995-08-07 1997-10-10 Pasteur Institut Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote

Also Published As

Publication number Publication date
US6200800B1 (en) 2001-03-13
EP1760154A3 (de) 2007-03-14
ATE477326T1 (de) 2010-08-15
JP4173543B2 (ja) 2008-10-29
FR2737731A1 (fr) 1997-02-14
FR2737731B1 (fr) 1997-10-10
CA2226301A1 (fr) 1997-02-20
DE69638235D1 (de) 2010-09-23
WO1997006271A1 (fr) 1997-02-20
JP4482578B2 (ja) 2010-06-16
EP0843732B1 (de) 2006-09-13
ATE339511T1 (de) 2006-10-15
US20060269522A1 (en) 2006-11-30
ES2276407T3 (es) 2007-06-16
EP1760154B1 (de) 2010-08-11
DE69636546T2 (de) 2007-08-02
JP2008086321A (ja) 2008-04-17
EP1760154A2 (de) 2007-03-07
PT843732E (pt) 2007-01-31
CA2226301C (fr) 2011-04-19
DK0843732T3 (da) 2007-01-22
EP0843732A1 (de) 1998-05-27
HK1105662A1 (en) 2008-02-22
JPH11510391A (ja) 1999-09-14

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