DE69633664D1 - Genetische marker für brust und eierstockkrebs - Google Patents
Genetische marker für brust und eierstockkrebsInfo
- Publication number
- DE69633664D1 DE69633664D1 DE69633664T DE69633664T DE69633664D1 DE 69633664 D1 DE69633664 D1 DE 69633664D1 DE 69633664 T DE69633664 T DE 69633664T DE 69633664 T DE69633664 T DE 69633664T DE 69633664 D1 DE69633664 D1 DE 69633664D1
- Authority
- DE
- Germany
- Prior art keywords
- specific
- mutations
- brca1
- antibodies
- diagnostic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US425061 | 1995-04-19 | ||
US08/425,061 US5622829A (en) | 1993-12-08 | 1995-04-19 | Genetic markers for breast, ovarian, and prostatic cancer |
PCT/US1996/005621 WO1996033271A2 (en) | 1995-04-19 | 1996-04-19 | Genetic markers for breast and ovarian cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69633664D1 true DE69633664D1 (de) | 2004-11-25 |
DE69633664T2 DE69633664T2 (de) | 2006-02-23 |
Family
ID=23684980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69633664T Expired - Lifetime DE69633664T2 (de) | 1995-04-19 | 1996-04-19 | Genetische marker für brust und eierstockkrebs |
Country Status (9)
Country | Link |
---|---|
US (3) | US5622829A (de) |
EP (1) | EP0821733B1 (de) |
JP (1) | JPH11503915A (de) |
AT (1) | ATE280226T1 (de) |
AU (1) | AU698800B2 (de) |
CA (1) | CA2217668C (de) |
DE (1) | DE69633664T2 (de) |
ES (1) | ES2231808T3 (de) |
WO (1) | WO1996033271A2 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040014051A1 (en) * | 2002-07-18 | 2004-01-22 | Isis Pharmaceuticals Inc. | Antisense modulation of breast cancer-1 expression |
US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
US5622829A (en) * | 1993-12-08 | 1997-04-22 | The Regents Of The University Of California | Genetic markers for breast, ovarian, and prostatic cancer |
US6210941B1 (en) | 1997-06-27 | 2001-04-03 | The Trustees Of Boston University | Methods for the detection and isolation of proteins |
US5643722A (en) | 1994-05-11 | 1997-07-01 | Trustees Of Boston University | Methods for the detection and isolation of proteins |
US6403303B1 (en) * | 1996-05-14 | 2002-06-11 | Visible Genetics Inc. | Method and reagents for testing for mutations in the BRCA1 gene |
US6428955B1 (en) | 1995-03-17 | 2002-08-06 | Sequenom, Inc. | DNA diagnostics based on mass spectrometry |
US5830655A (en) | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
US6083698A (en) * | 1995-09-25 | 2000-07-04 | Oncormed, Inc. | Cancer susceptibility mutations of BRCA1 |
DE19629938C1 (de) * | 1996-07-24 | 1997-11-27 | Gsf Forschungszentrum Umwelt | E-Cadherin-Mutationen als Grundlage zur Diagnostik und Therapie humaner maligner Tumoren |
US5905026A (en) | 1996-08-27 | 1999-05-18 | Cornell Research Foundation, Inc. | Method of detecting expression of and isolating the protein encoded by the BRCA1 gene |
WO1998012327A2 (en) * | 1996-09-20 | 1998-03-26 | Board Of Regents, The University Of Texas System | Compositions and methods comprising bard1 and other brca1 binding proteins |
AU5093898A (en) * | 1996-10-31 | 1998-05-22 | Jennifer Lescallett | Primers for amplification of brca1 |
WO1998020166A2 (en) * | 1996-11-06 | 1998-05-14 | Sequenom, Inc. | Dna diagnostics based on mass spectrometry |
US5965377A (en) * | 1997-03-24 | 1999-10-12 | Baystate Medical Center | Method for determining the presence of mutated BRCA protein |
EP0878552A1 (de) * | 1997-05-13 | 1998-11-18 | Erasmus Universiteit Rotterdam | Molekularer Nachweis von chromosomalen Veränderungen |
EP0983389A1 (de) * | 1997-06-04 | 2000-03-08 | Rijksuniversiteit te Leiden | Testsatz und verfahren für den nachweis von einer rädisposition zum ovarial und brustkrebs |
US7014993B1 (en) * | 1997-08-21 | 2006-03-21 | The Board Of Trustees Of The University Of Arkansas | Extracellular serine protease |
US6207370B1 (en) | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
US6030832A (en) * | 1997-11-21 | 2000-02-29 | Myriad Genetics, Inc. | Carboxy-terminal BRCA1 interacting protein |
EP1078098A1 (de) * | 1998-05-04 | 2001-02-28 | Dako A/S | Verfahren und sonden zur detektion chromosomaler aberrationen |
US6723564B2 (en) | 1998-05-07 | 2004-04-20 | Sequenom, Inc. | IR MALDI mass spectrometry of nucleic acids using liquid matrices |
DK1520588T3 (en) | 1998-07-13 | 2015-03-23 | Univ Texas | Use of antibodies to aminophospholipids for cancer treatment |
US7226731B1 (en) | 1998-07-24 | 2007-06-05 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | PB 39, a gene dysregulated in prostate cancer, and uses thereof |
AU5128799A (en) * | 1998-07-24 | 2000-02-14 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Pb 39, a gene dysregulated in prostate cancer, and uses thereof |
EP1234585A3 (de) | 1998-09-04 | 2004-01-21 | The Regents Of The University Of Michigan | Zusammensetzungen zur Vorbeugung oder Behandlung von Krebs |
WO2000075161A2 (en) | 1999-06-04 | 2000-12-14 | Massachusetts Institute Of Technology | Compositions and methods for the screening of compounds to enhance or reduce apoptosis |
US6306628B1 (en) | 1999-08-25 | 2001-10-23 | Ambergen, Incorporated | Methods for the detection, analysis and isolation of Nascent proteins |
US20030064372A1 (en) * | 2000-06-22 | 2003-04-03 | Bodnar Jackie S. | Gene and sequence variation associated with lipid disorder |
US6703204B1 (en) | 2000-07-28 | 2004-03-09 | The Brigham & Women's Hospital, Inc. | Prognostic classification of breast cancer through determination of nucleic acid sequence expression |
WO2002010436A2 (en) * | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
US7465540B2 (en) * | 2000-09-21 | 2008-12-16 | Luminex Corporation | Multiple reporter read-out for bioassays |
US20030188326A1 (en) | 2000-11-03 | 2003-10-02 | Dana Farber Cancer Institute | Methods and compositions for the diagnosis of cancer susceptibilities and defective DNA repair mechanisms and treatment thereof |
WO2002099418A1 (en) * | 2001-06-04 | 2002-12-12 | Research Development Foundation | Premalignant, serially-transplantable breast tissue lines and uses thereof |
AU2003253629A1 (en) * | 2002-06-07 | 2003-12-22 | Myriad Genetics, Inc | Large deletions in human brca1 gene and use thereof |
MX337052B (es) | 2002-07-15 | 2016-02-11 | Univ Texas | Peptidos que se enlazan a fosfatidiletanolamina y sus usos en el tratamiento de infecciones virales y del cancer. |
US8431396B2 (en) | 2003-03-21 | 2013-04-30 | The Cleveland Clinic Foundation | Anti-angiogenic peptides |
MXPA06008293A (es) | 2004-01-22 | 2007-06-11 | Univ Miami | Formulaciones topicas de coenzima q10 y metodos de uso. |
BRPI0820298A8 (pt) | 2007-11-09 | 2018-05-08 | Affitech Res As | composições e métodos de anticorpos anti-vegf |
US8167949B2 (en) * | 2008-01-25 | 2012-05-01 | Aesculap Implant Systems, Llc | Hydrostatic interbody |
CN111253483B (zh) * | 2020-03-02 | 2021-07-30 | 江苏莱森生物科技研究院有限公司 | 一种抗brca1单克隆抗体及其用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4742000A (en) * | 1986-05-02 | 1988-05-03 | University Of Chicago | Antibody to human progesterone receptor and diagnostic materials and methods |
ES2164045T3 (es) * | 1990-06-27 | 2002-02-16 | Univ Princeton | Sondas para la deteccion de p53 mutante. |
US5597707A (en) * | 1993-04-15 | 1997-01-28 | Bristol-Myers Squibb Company | Tumor associated antigen recognized by the murine monoclonal antibody L6, its oligonucleotide sequence and methods for their use |
US5622829A (en) * | 1993-12-08 | 1997-04-22 | The Regents Of The University Of California | Genetic markers for breast, ovarian, and prostatic cancer |
WO1995019369A1 (en) * | 1994-01-14 | 1995-07-20 | Vanderbilt University | Method for detection and treatment of breast cancer |
-
1995
- 1995-04-19 US US08/425,061 patent/US5622829A/en not_active Expired - Lifetime
-
1996
- 1996-04-19 EP EP96913045A patent/EP0821733B1/de not_active Expired - Lifetime
- 1996-04-19 WO PCT/US1996/005621 patent/WO1996033271A2/en active IP Right Grant
- 1996-04-19 CA CA002217668A patent/CA2217668C/en not_active Expired - Lifetime
- 1996-04-19 JP JP8531995A patent/JPH11503915A/ja not_active Withdrawn
- 1996-04-19 AT AT96913045T patent/ATE280226T1/de not_active IP Right Cessation
- 1996-04-19 AU AU55668/96A patent/AU698800B2/en not_active Expired
- 1996-04-19 ES ES96913045T patent/ES2231808T3/es not_active Expired - Lifetime
- 1996-04-19 DE DE69633664T patent/DE69633664T2/de not_active Expired - Lifetime
-
1997
- 1997-04-02 US US08/825,886 patent/US5821328A/en not_active Expired - Lifetime
- 1997-12-12 US US08/989,890 patent/US6512091B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU698800B2 (en) | 1998-11-05 |
WO1996033271A2 (en) | 1996-10-24 |
AU5566896A (en) | 1996-11-07 |
EP0821733B1 (de) | 2004-10-20 |
JPH11503915A (ja) | 1999-04-06 |
ES2231808T3 (es) | 2005-05-16 |
ATE280226T1 (de) | 2004-11-15 |
EP0821733A2 (de) | 1998-02-04 |
DE69633664T2 (de) | 2006-02-23 |
WO1996033271A3 (en) | 1997-03-20 |
US5622829A (en) | 1997-04-22 |
CA2217668A1 (en) | 1996-10-24 |
US6512091B1 (en) | 2003-01-28 |
US5821328A (en) | 1998-10-13 |
CA2217668C (en) | 1999-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |