DE69630594D1 - Verfahren und mittel zur in-vivo erkennung von mundhöhlenkrebs und von präkanzerösen zuständen - Google Patents

Verfahren und mittel zur in-vivo erkennung von mundhöhlenkrebs und von präkanzerösen zuständen

Info

Publication number
DE69630594D1
DE69630594D1 DE69630594T DE69630594T DE69630594D1 DE 69630594 D1 DE69630594 D1 DE 69630594D1 DE 69630594 T DE69630594 T DE 69630594T DE 69630594 T DE69630594 T DE 69630594T DE 69630594 D1 DE69630594 D1 DE 69630594D1
Authority
DE
Germany
Prior art keywords
pct
precaneus
states
oral cancer
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69630594T
Other languages
English (en)
Other versions
DE69630594T2 (de
Inventor
Edwin Pomerantz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zila Inc
Original Assignee
Zila Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zila Inc filed Critical Zila Inc
Application granted granted Critical
Publication of DE69630594D1 publication Critical patent/DE69630594D1/de
Publication of DE69630594T2 publication Critical patent/DE69630594T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69630594T 1996-01-16 1996-01-16 Verfahren und mittel zur in-vivo erkennung von mundhöhlenkrebs und von präkanzerösen zuständen Expired - Fee Related DE69630594T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/000509 WO1997026018A1 (en) 1996-01-16 1996-01-16 Methods and compositions for in-vivo detection of oral cancers and precancerous conditions

Publications (2)

Publication Number Publication Date
DE69630594D1 true DE69630594D1 (de) 2003-12-11
DE69630594T2 DE69630594T2 (de) 2004-09-23

Family

ID=22254619

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69630594T Expired - Fee Related DE69630594T2 (de) 1996-01-16 1996-01-16 Verfahren und mittel zur in-vivo erkennung von mundhöhlenkrebs und von präkanzerösen zuständen

Country Status (12)

Country Link
US (1) US5882627A (de)
EP (1) EP0814847B1 (de)
JP (1) JPH10511702A (de)
KR (1) KR100342342B1 (de)
AT (1) ATE253380T1 (de)
AU (1) AU712732B2 (de)
CA (1) CA2214829C (de)
DE (1) DE69630594T2 (de)
DK (1) DK0814847T3 (de)
ES (1) ES2208727T3 (de)
PT (1) PT814847E (de)
WO (1) WO1997026018A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6086852A (en) * 1997-11-13 2000-07-11 Zila, Inc. In vivo stain composition, process of manufacture, and methods of use to identify dysplastic tissue
US6194573B1 (en) * 1997-11-13 2001-02-27 Zila, Inc. Process for manufacture of in vivo stain composition
EP1165087B1 (de) * 2000-01-31 2005-09-07 Zila, Inc. In vivo färbemittel und verwendungsmethoden zur identifizierung von dysplastischem gewebe
WO2001064110A1 (en) * 2000-02-28 2001-09-07 Zila, Inc. Method for detecting and killing epithelial cancer cells
MXPA02002183A (es) * 2000-06-30 2002-09-30 Zila Inc Agente de diagnostico de azul de metileno y metodos para la deteccion de cancer epitelial.
BR0013636A (pt) * 2000-06-30 2005-01-11 Zila Inc Uso de uma composição de rodamina para identificação e delineação do tecido epitelial canceroso
US6967015B1 (en) * 2000-07-20 2005-11-22 Zila, Inc. Diagnostic method for detecting dysplastic epithelial tissue
IL149330A0 (en) * 2000-09-26 2002-11-10 Zila Inc Method for early prediction of the onset of invasive cancer
US20040146919A1 (en) * 2002-05-18 2004-07-29 Burkett Douglas D. Method for early prediction of the onset of invasive cancer
US20030194374A1 (en) * 2001-01-17 2003-10-16 Xanodyne Pharmacal, Inc. Compositions including a visual marker and method of use thereof
US7062312B2 (en) * 2001-01-17 2006-06-13 Pediamed Pharmaceuticals, Inc. Combination and method including a visual marker for determining compliance with a medication regimen
GB0113121D0 (en) * 2001-05-30 2001-07-18 Univ Leeds Biologically active photosensitisers
CA2457407A1 (en) * 2001-12-14 2003-07-17 Zila, Inc. Light-directed molecular analysis for cancer prognosis and diagnosis
US20030120180A1 (en) * 2001-12-21 2003-06-26 Kimberly-Clark Worldwide, Inc. Method and apparatus for collecting and testing biological samples
US20030017158A1 (en) * 2002-03-08 2003-01-23 Bernal Samuel D. Method for detecting and killing epithelial cancer cells
US7910531B2 (en) * 2004-06-17 2011-03-22 C2C Technologies Llc Composition and method for producing colored bubbles
CA2583427A1 (en) * 2004-09-30 2006-04-20 Zila Biotechnology, Inc. Light-directed method for detecting and aiding further evaluation of abnormal mucosal tissue
EP1835929B8 (de) 2005-01-06 2016-07-27 Novo Nordisk A/S Behandlungen und verfahren mit anti-kir-kombination
US20060236470A1 (en) * 2005-03-29 2006-10-26 Sabnis Ram W Novelty compositions with color changing indicator
US20060222601A1 (en) * 2005-03-29 2006-10-05 Sabnis Ram W Oral care compositions with color changing indicator
US20060257439A1 (en) * 2005-03-29 2006-11-16 Sabnis Ram W Cleansing compositions with color changing indicator
US20060222675A1 (en) * 2005-03-29 2006-10-05 Sabnis Ram W Personal care compositions with color changing indicator
US20070010400A1 (en) * 2005-07-06 2007-01-11 Sabnis Ram W Use of color changing indicators in consumer products
US20090023138A1 (en) * 2007-07-17 2009-01-22 Zila Biotechnology, Inc. Oral cancer markers and their detection

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053508B (it) * 1970-07-06 1981-10-10 Searle & Co Procedimento per prepare composizioni marcate adatte a mettere in evidenza alterazioni della mucosa gastrointestinale prodotto ottenuto e relativo metodo di impiego
US4321251A (en) * 1979-12-19 1982-03-23 The United States Of America As Represented By The Department Of Health And Human Services Detection of malignant lesions of the oral cavity utilizing toluidine blue rinse
US4950665A (en) * 1988-10-28 1990-08-21 Oklahoma Medical Research Foundation Phototherapy using methylene blue
DE69229471T2 (de) * 1991-10-31 1999-11-25 Zila Inc Biologische färbemittelzusammensetzung, verfarren zu seiner herstellung und verwendung zur markierung der umrisse von epithel karsinomen
AU696368B2 (en) * 1993-01-14 1998-09-10 Zila Biotechnology, Inc. Method and kit for epithelial cancer screening

Also Published As

Publication number Publication date
ATE253380T1 (de) 2003-11-15
CA2214829C (en) 2002-05-14
EP0814847B1 (de) 2003-11-05
ES2208727T3 (es) 2004-06-16
DK0814847T3 (da) 2004-03-15
AU4856496A (en) 1997-08-11
US5882627A (en) 1999-03-16
KR19980702985A (ko) 1998-09-05
CA2214829A1 (en) 1997-07-24
KR100342342B1 (ko) 2002-08-22
JPH10511702A (ja) 1998-11-10
AU712732B2 (en) 1999-11-11
PT814847E (pt) 2004-03-31
WO1997026018A1 (en) 1997-07-24
EP0814847A1 (de) 1998-01-07
EP0814847A4 (de) 2000-05-03
DE69630594T2 (de) 2004-09-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee