DE69629815D1 - Verfahren zur herstellung von penicilling-phenylester - Google Patents

Verfahren zur herstellung von penicilling-phenylester

Info

Publication number
DE69629815D1
DE69629815D1 DE69629815T DE69629815T DE69629815D1 DE 69629815 D1 DE69629815 D1 DE 69629815D1 DE 69629815 T DE69629815 T DE 69629815T DE 69629815 T DE69629815 T DE 69629815T DE 69629815 D1 DE69629815 D1 DE 69629815D1
Authority
DE
Germany
Prior art keywords
producing
penicilling
phenylester
chem
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69629815T
Other languages
English (en)
Other versions
DE69629815T2 (de
Inventor
Satoru Takahashi
Atsushi Yamamura
Hisashi Hayashida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Schering Plough Animal Health KK
Original Assignee
Takeda Schering Plough Animal Health KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Schering Plough Animal Health KK filed Critical Takeda Schering Plough Animal Health KK
Application granted granted Critical
Publication of DE69629815D1 publication Critical patent/DE69629815D1/de
Publication of DE69629815T2 publication Critical patent/DE69629815T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/08—Modification of a carboxyl radical directly attached in position 2, e.g. esterification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69629815T 1995-06-14 1996-06-13 Verfahren zur herstellung von penicilling-phenylester Expired - Fee Related DE69629815T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP14752895 1995-06-14
JP14752895 1995-06-14
JP8078296 1996-03-07
JP8078296 1996-03-07
PCT/JP1996/001604 WO1997000259A1 (fr) 1995-06-14 1996-06-13 Procede ameliore de production de phenyl-ester de penicilline g

Publications (2)

Publication Number Publication Date
DE69629815D1 true DE69629815D1 (de) 2003-10-09
DE69629815T2 DE69629815T2 (de) 2004-04-08

Family

ID=26421757

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69629815T Expired - Fee Related DE69629815T2 (de) 1995-06-14 1996-06-13 Verfahren zur herstellung von penicilling-phenylester

Country Status (10)

Country Link
EP (1) EP0837066B1 (de)
JP (1) JP3377795B2 (de)
KR (1) KR100402595B1 (de)
CN (1) CN1092661C (de)
AT (1) ATE248841T1 (de)
DE (1) DE69629815T2 (de)
DK (1) DK0837066T3 (de)
ES (1) ES2205034T3 (de)
PT (1) PT837066E (de)
WO (1) WO1997000259A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5419119B2 (ja) * 2007-08-20 2014-02-19 国立大学法人名古屋大学 エステルの製造法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD150393A3 (de) * 1978-04-05 1981-09-02 Wolfgang Krueger Verfahren zur herstellung halbsynthetischer penicilline und ihrer alkalisalze
US5112967A (en) * 1990-04-27 1992-05-12 Hoffmann-La Roches Inc. Process for synthesizing antibacterial cephalosporin compounds
JP2952015B2 (ja) * 1990-08-28 1999-09-20 大塚化学株式会社 ペニシリン類のエステル化方法
WO1993008196A1 (en) * 1991-10-15 1993-04-29 Fujisawa Pharmaceutical Co., Ltd. Penicillin g ester

Also Published As

Publication number Publication date
CN1187822A (zh) 1998-07-15
CN1092661C (zh) 2002-10-16
EP0837066A1 (de) 1998-04-22
DK0837066T3 (da) 2003-11-24
ES2205034T3 (es) 2004-05-01
DE69629815T2 (de) 2004-04-08
KR100402595B1 (ko) 2005-09-02
EP0837066A4 (de) 1998-11-25
WO1997000259A1 (fr) 1997-01-03
ATE248841T1 (de) 2003-09-15
PT837066E (pt) 2004-01-30
KR19990014793A (ko) 1999-02-25
JP3377795B2 (ja) 2003-02-17
EP0837066B1 (de) 2003-09-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee