DE69628585D1 - Verfahren zur herstellung von heparinisierten biomaterialien - Google Patents

Verfahren zur herstellung von heparinisierten biomaterialien

Info

Publication number
DE69628585D1
DE69628585D1 DE69628585T DE69628585T DE69628585D1 DE 69628585 D1 DE69628585 D1 DE 69628585D1 DE 69628585 T DE69628585 T DE 69628585T DE 69628585 T DE69628585 T DE 69628585T DE 69628585 D1 DE69628585 D1 DE 69628585D1
Authority
DE
Germany
Prior art keywords
heparinized
biomaterials
producing
producing heparinized
heparinized biomaterials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69628585T
Other languages
English (en)
Other versions
DE69628585T2 (de
Inventor
Michel Verhoeven
L Cahalan
Marc Hendriks
Benedicte Fouache
T Cahalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Publication of DE69628585D1 publication Critical patent/DE69628585D1/de
Application granted granted Critical
Publication of DE69628585T2 publication Critical patent/DE69628585T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0023—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a quaternized group or a protonated amine group of the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/921—Blood vessel

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
DE69628585T 1995-08-22 1996-08-12 Verfahren zur herstellung von heparinisierten biomaterialien Expired - Fee Related DE69628585T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/518,084 US5679659A (en) 1995-08-22 1995-08-22 Method for making heparinized biomaterials
US518084 1995-08-22
PCT/US1996/012996 WO1997007834A2 (en) 1995-08-22 1996-08-12 Method for making heparinized biomaterials

Publications (2)

Publication Number Publication Date
DE69628585D1 true DE69628585D1 (de) 2003-07-10
DE69628585T2 DE69628585T2 (de) 2004-04-29

Family

ID=24062487

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628585T Expired - Fee Related DE69628585T2 (de) 1995-08-22 1996-08-12 Verfahren zur herstellung von heparinisierten biomaterialien

Country Status (6)

Country Link
US (1) US5679659A (de)
EP (1) EP0874648B1 (de)
JP (1) JPH11511355A (de)
AU (1) AU6951796A (de)
DE (1) DE69628585T2 (de)
WO (1) WO1997007834A2 (de)

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US6241762B1 (en) 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US6258371B1 (en) 1998-04-03 2001-07-10 Medtronic Inc Method for making biocompatible medical article
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US20070087028A1 (en) * 1998-04-16 2007-04-19 Robert Falotico Intraluminal devices for the prevention and treatment of vascular disease
US6248127B1 (en) * 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
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US6416548B2 (en) 1999-07-20 2002-07-09 Sulzer Carbomedics Inc. Antimicrobial annuloplasty ring having a biodegradable insert
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DE60133053T2 (de) 2000-10-16 2009-02-26 Conor Medsystems, Inc., Menlo Park Ausdehnbare medizinische Vorrichtung zur Abgabe eines nützlichen Agens
US6630460B2 (en) * 2001-02-09 2003-10-07 Medtronic, Inc. Heparin compositions and methods of making and using the same
US8182527B2 (en) 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
US20030065382A1 (en) * 2001-10-02 2003-04-03 Fischell Robert E. Means and method for the treatment of coronary artery obstructions
US20040236415A1 (en) * 2003-01-02 2004-11-25 Richard Thomas Medical devices having drug releasing polymer reservoirs
US20040243224A1 (en) * 2003-04-03 2004-12-02 Medtronic Vascular, Inc. Methods and compositions for inhibiting narrowing in mammalian vascular pathways
US20050154455A1 (en) * 2003-12-18 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050154451A1 (en) * 2003-12-18 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050137683A1 (en) * 2003-12-19 2005-06-23 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050152942A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050152943A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050152940A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050154452A1 (en) * 2003-12-23 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050159809A1 (en) * 2004-01-21 2005-07-21 Medtronic Vascular, Inc. Implantable medical devices for treating or preventing restenosis
US20050228490A1 (en) * 2004-04-09 2005-10-13 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050261762A1 (en) * 2004-05-21 2005-11-24 Medtronic Vascular, Inc. Medical devices to prevent or inhibit restenosis
US20060062822A1 (en) * 2004-09-21 2006-03-23 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20060088571A1 (en) * 2004-10-21 2006-04-27 Medtronic Vascular, Inc. Biocompatible and hemocompatible polymer compositions
US20070027530A1 (en) * 2005-07-26 2007-02-01 Medtronic Vascular, Inc. Intraluminal device, catheter assembly, and method of use thereof
US20070067020A1 (en) * 2005-09-22 2007-03-22 Medtronic Vasular, Inc. Intraluminal stent, delivery system, and a method of treating a vascular condition
US20070239267A1 (en) * 2006-03-28 2007-10-11 Medtronic Vascular, Inc. Stent Graft With Healing Promoting Necks
US20070231361A1 (en) * 2006-03-28 2007-10-04 Medtronic Vascular, Inc. Use of Fatty Acids to Inhibit the Growth of Aneurysms
US8986713B2 (en) 2006-05-12 2015-03-24 W. L. Gore & Associates, Inc. Medical device capable of being compacted and expanded having anti-thrombin III binding activity
US8496953B2 (en) 2006-05-12 2013-07-30 W. L. Gore & Associates, Inc. Immobilized biologically active entities having a high degree of biological activity following sterilization
US8021677B2 (en) 2006-05-12 2011-09-20 Gore Enterprise Holdings, Inc. Immobilized biologically active entities having a high degree of biological activity
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CN103596603B (zh) 2011-03-11 2016-01-20 W.L.戈尔及同仁股份有限公司 固定的生物实体的改进
CN105744967B (zh) * 2013-11-28 2018-12-25 东丽株式会社 抗血栓性材料
CN115252901B (zh) * 2021-04-30 2023-11-21 沛嘉医疗科技(苏州)有限公司 一种改性生物瓣膜材料的制备方法和改性生物瓣膜材料

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Also Published As

Publication number Publication date
US5679659A (en) 1997-10-21
AU6951796A (en) 1997-03-19
EP0874648B1 (de) 2003-06-04
EP0874648A2 (de) 1998-11-04
JPH11511355A (ja) 1999-10-05
WO1997007834A2 (en) 1997-03-06
WO1997007834A3 (en) 1997-03-27
DE69628585T2 (de) 2004-04-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee