DE69627202D1 - Behandlung von roten blutzellen zur inaktivierung von virien durch verwendung von pathalocyanine und rotlicht - Google Patents
Behandlung von roten blutzellen zur inaktivierung von virien durch verwendung von pathalocyanine und rotlichtInfo
- Publication number
- DE69627202D1 DE69627202D1 DE69627202T DE69627202T DE69627202D1 DE 69627202 D1 DE69627202 D1 DE 69627202D1 DE 69627202 T DE69627202 T DE 69627202T DE 69627202 T DE69627202 T DE 69627202T DE 69627202 D1 DE69627202 D1 DE 69627202D1
- Authority
- DE
- Germany
- Prior art keywords
- red blood
- phthalocyanine
- blood cells
- red
- blood cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000003743 erythrocyte Anatomy 0.000 title abstract 10
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical compound N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 2
- 238000001720 action spectrum Methods 0.000 abstract 2
- 230000005779 cell damage Effects 0.000 abstract 1
- 208000037887 cell injury Diseases 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- JACPFCQFVIAGDN-UHFFFAOYSA-M sipc iv Chemical compound [OH-].[Si+4].CN(C)CCC[Si](C)(C)[O-].C=1C=CC=C(C(N=C2[N-]C(C3=CC=CC=C32)=N2)=N3)C=1C3=CC([C]1C=CC=CC1=1)=NC=1N=C1[C]3C=CC=CC3=C2[N-]1 JACPFCQFVIAGDN-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
- A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
- A61M2205/052—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy infrared
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US730695P | 1995-11-06 | 1995-11-06 | |
PCT/US1996/017528 WO1997016966A1 (en) | 1995-11-06 | 1996-11-04 | Viral inactivation treatment of red blood cells using phthalocyanines and red light |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69627202D1 true DE69627202D1 (de) | 2003-05-08 |
DE69627202T2 DE69627202T2 (de) | 2003-11-13 |
Family
ID=21725402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69627202T Expired - Lifetime DE69627202T2 (de) | 1995-11-06 | 1996-11-04 | Behandlung von roten blutzellen zur inaktivierung von virien durch verwendung von pathalocyanine und rotlicht |
Country Status (8)
Country | Link |
---|---|
US (1) | US6090599A (de) |
EP (1) | EP0881874B1 (de) |
JP (1) | JP2000500137A (de) |
AT (1) | ATE235814T1 (de) |
AU (1) | AU723016B2 (de) |
CA (1) | CA2236873A1 (de) |
DE (1) | DE69627202T2 (de) |
WO (1) | WO1997016966A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2767123B1 (fr) | 1997-08-05 | 1999-10-29 | Schmalbach Lubeca Pet Centre T | Nouvelle structure de recipient et procede de conditionnement d'un produit au moyen de ce recipient |
WO1999034839A1 (en) | 1998-01-06 | 1999-07-15 | Cerus Corporation | Methods for quenching pathogen inactivators in biological materials |
US20030180291A1 (en) * | 1998-06-23 | 2003-09-25 | Johnny Van Steveninck | Method of inactivating viruses |
US6511971B1 (en) * | 1998-10-13 | 2003-01-28 | Brown University Research Foundation | Substituted perhalogenated phthalocyanines |
PT2130554E (pt) | 1999-02-22 | 2012-11-19 | Univ Connecticut | Formulações de factor viii isentas de albumina |
US6409719B1 (en) | 2000-09-18 | 2002-06-25 | Don A. Manning | Light stint implant device for treatment of long term viral infection |
CN103961731B (zh) | 2004-10-29 | 2017-01-18 | 塞鲁斯公司 | 用于红细胞灭活过程的改进的猝灭方法 |
CN102046006B (zh) | 2008-04-09 | 2014-09-24 | 塞鲁斯公司 | 用于红细胞病原体灭活的改进猝灭方法 |
US20100168018A1 (en) | 2008-11-07 | 2010-07-01 | Baxter International Inc. | Factor viii formulations |
EP2645854B1 (de) | 2010-11-29 | 2017-10-18 | New York Blood Center, Inc. | Verfahren zur sammlung und lagerung von blut |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4878891A (en) * | 1987-06-25 | 1989-11-07 | Baylor Research Foundation | Method for eradicating infectious biological contaminants in body tissues |
US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
CN1039283C (zh) * | 1988-12-12 | 1998-07-29 | Fmc公司 | 卟啉的应用 |
US5238940A (en) * | 1990-03-22 | 1993-08-24 | Quadra Logic Technologies Inc. | Compositions for photodynamic therapy |
US5516629A (en) * | 1990-04-16 | 1996-05-14 | Cryopharm Corporation | Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins |
US5232844A (en) * | 1990-05-15 | 1993-08-03 | New York Blood Center | Photodynamic inactivation of viruses in cell-containing compositions |
US5120649A (en) * | 1990-05-15 | 1992-06-09 | New York Blood Center, Inc. | Photodynamic inactivation of viruses in blood cell-containing compositions |
US5484778C1 (en) * | 1990-07-17 | 2001-05-08 | Univ Cleveland Hospitals | Phthalocynine photosensitizers for photodynamic therapy and methods for their use |
DK0660712T3 (da) * | 1992-09-21 | 2001-08-27 | Quadra Logic Tech Inc | Transcutation in vivo-aktivering af lysfølsomme midler i blod |
EP0680365B1 (de) * | 1992-11-20 | 2000-03-01 | The University Of British Columbia | Aktivierung von photoempfindlichen mitteln |
US5556612A (en) * | 1994-03-15 | 1996-09-17 | The General Hospital Corporation | Methods for phototherapeutic treatment of proliferative skin diseases |
-
1996
- 1996-11-04 DE DE69627202T patent/DE69627202T2/de not_active Expired - Lifetime
- 1996-11-04 US US09/068,230 patent/US6090599A/en not_active Expired - Lifetime
- 1996-11-04 AU AU76672/96A patent/AU723016B2/en not_active Ceased
- 1996-11-04 WO PCT/US1996/017528 patent/WO1997016966A1/en active IP Right Grant
- 1996-11-04 CA CA002236873A patent/CA2236873A1/en not_active Abandoned
- 1996-11-04 AT AT96939527T patent/ATE235814T1/de not_active IP Right Cessation
- 1996-11-04 JP JP9518242A patent/JP2000500137A/ja active Pending
- 1996-11-04 EP EP96939527A patent/EP0881874B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0881874B1 (de) | 2003-04-02 |
CA2236873A1 (en) | 1997-05-15 |
EP0881874A1 (de) | 1998-12-09 |
AU7667296A (en) | 1997-05-29 |
DE69627202T2 (de) | 2003-11-13 |
US6090599A (en) | 2000-07-18 |
WO1997016966A1 (en) | 1997-05-15 |
EP0881874A4 (de) | 2000-09-27 |
AU723016B2 (en) | 2000-08-17 |
JP2000500137A (ja) | 2000-01-11 |
ATE235814T1 (de) | 2003-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |