DE69626507T2 - Lhrh-antagonisten - Google Patents

Lhrh-antagonisten

Info

Publication number
DE69626507T2
DE69626507T2 DE69626507T DE69626507T DE69626507T2 DE 69626507 T2 DE69626507 T2 DE 69626507T2 DE 69626507 T DE69626507 T DE 69626507T DE 69626507 T DE69626507 T DE 69626507T DE 69626507 T2 DE69626507 T2 DE 69626507T2
Authority
DE
Germany
Prior art keywords
lhrh antagonist
analogs
lhrh
congeners
dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69626507T
Other languages
English (en)
Other versions
DE69626507D1 (de
Inventor
Y Bowers
A Folkers
Anna Janecka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
University of Texas System
Original Assignee
Tulane University
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tulane University, University of Texas System filed Critical Tulane University
Application granted granted Critical
Publication of DE69626507D1 publication Critical patent/DE69626507D1/de
Publication of DE69626507T2 publication Critical patent/DE69626507T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE69626507T 1995-04-28 1996-04-26 Lhrh-antagonisten Expired - Fee Related DE69626507T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/430,602 US5656727A (en) 1992-09-15 1995-04-28 Antagonists of LHRH
PCT/US1996/005682 WO1996033729A1 (en) 1995-04-28 1996-04-26 Antagonists of lhrh

Publications (2)

Publication Number Publication Date
DE69626507D1 DE69626507D1 (de) 2003-04-10
DE69626507T2 true DE69626507T2 (de) 2003-11-13

Family

ID=23708267

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626507T Expired - Fee Related DE69626507T2 (de) 1995-04-28 1996-04-26 Lhrh-antagonisten

Country Status (10)

Country Link
US (1) US5656727A (de)
EP (1) EP0822827B1 (de)
JP (1) JPH11504335A (de)
AT (1) ATE233567T1 (de)
AU (1) AU703400B2 (de)
CA (1) CA2219263A1 (de)
DE (1) DE69626507T2 (de)
ES (1) ES2191753T3 (de)
PT (1) PT822827E (de)
WO (1) WO1996033729A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2915574C (en) 2003-07-18 2017-02-07 Oakwood Laboratories, L.L.C. Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
WO2006010155A2 (en) 2004-07-16 2006-01-26 Oakwood Laboratories, L.L.C Gonadotropin releasing hormone antagonists
ES2673822T3 (es) * 2006-07-18 2018-06-25 Sanofi Anticuerpo antagonista contra EphA2 para el tratamiento de cáncer
KR101642363B1 (ko) 2008-06-12 2016-07-25 입센 바이오이노베이션 리미티드 신경내분비계 질환의 억제
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872484A (en) * 1956-05-21 1959-02-03 American Cyanamid Co Preparation of tetraalkyl-isothioureas
US4431635A (en) * 1979-06-13 1984-02-14 Coy David Howard LH-RH Antagonists
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
US4504414A (en) * 1983-03-28 1985-03-12 Board Of Regents, The University Of Texas System Synthetic pyridyl-alanyl decapeptides having antiovulatory activity
US4530920A (en) * 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
US4652550A (en) * 1984-05-21 1987-03-24 The Salk Institute For Biological Studies GnRH antagonists VII
IL74827A (en) * 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
US4647653A (en) * 1984-08-23 1987-03-03 Tulane Educational Fund Therapeutic peptides
US4565804A (en) * 1984-09-07 1986-01-21 The Salk Institute For Biological Studies GnRH Antagonists VI
ZA862570B (en) * 1985-04-09 1986-12-30 Univ Tulane Therapeutic decapeptides
AU5638886A (en) * 1985-04-19 1986-10-23 Syntex (U.S.A.) Inc. Contraceptive methods for dogs using the decapeptide lhrh
EP0225746A3 (de) * 1985-11-14 1989-12-20 The Administrators of The Tulane Educational Fund Therapeutische Dekapeptide
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4851385A (en) * 1987-07-15 1989-07-25 Indiana University Foundation LHRH antagonist analogs having low histamine-release activity
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists
EP0328090A3 (de) * 1988-02-10 1990-08-16 Abbott Laboratories LHRH-Analoge
US5300492A (en) * 1988-02-10 1994-04-05 Tap Pharmaceuticals LHRH analogs

Also Published As

Publication number Publication date
ES2191753T3 (es) 2003-09-16
JPH11504335A (ja) 1999-04-20
EP0822827B1 (de) 2003-03-05
WO1996033729A1 (en) 1996-10-31
AU5667096A (en) 1996-11-18
EP0822827A1 (de) 1998-02-11
ATE233567T1 (de) 2003-03-15
CA2219263A1 (en) 1996-10-31
EP0822827A4 (de) 2001-07-11
PT822827E (pt) 2003-07-31
AU703400B2 (en) 1999-03-25
US5656727A (en) 1997-08-12
DE69626507D1 (de) 2003-04-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee