ATE233567T1 - Lhrh-antagonisten - Google Patents

Lhrh-antagonisten

Info

Publication number
ATE233567T1
ATE233567T1 AT96913829T AT96913829T ATE233567T1 AT E233567 T1 ATE233567 T1 AT E233567T1 AT 96913829 T AT96913829 T AT 96913829T AT 96913829 T AT96913829 T AT 96913829T AT E233567 T1 ATE233567 T1 AT E233567T1
Authority
AT
Austria
Prior art keywords
lhrh antagonists
lhrh
analogs
congeners
dosage
Prior art date
Application number
AT96913829T
Other languages
English (en)
Inventor
Cyril Y Bowers
Karl A Folkers
Anna Janecka
Original Assignee
Univ Texas
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Univ Tulane filed Critical Univ Texas
Application granted granted Critical
Publication of ATE233567T1 publication Critical patent/ATE233567T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT96913829T 1995-04-28 1996-04-26 Lhrh-antagonisten ATE233567T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/430,602 US5656727A (en) 1992-09-15 1995-04-28 Antagonists of LHRH
PCT/US1996/005682 WO1996033729A1 (en) 1995-04-28 1996-04-26 Antagonists of lhrh

Publications (1)

Publication Number Publication Date
ATE233567T1 true ATE233567T1 (de) 2003-03-15

Family

ID=23708267

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96913829T ATE233567T1 (de) 1995-04-28 1996-04-26 Lhrh-antagonisten

Country Status (10)

Country Link
US (1) US5656727A (de)
EP (1) EP0822827B1 (de)
JP (1) JPH11504335A (de)
AT (1) ATE233567T1 (de)
AU (1) AU703400B2 (de)
CA (1) CA2219263A1 (de)
DE (1) DE69626507T2 (de)
ES (1) ES2191753T3 (de)
PT (1) PT822827E (de)
WO (1) WO1996033729A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343513B2 (en) 2003-07-18 2013-01-01 Oakwood Laboratories, Llc Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
WO2006010155A2 (en) 2004-07-16 2006-01-26 Oakwood Laboratories, L.L.C Gonadotropin releasing hormone antagonists
NZ574215A (en) * 2006-07-18 2012-07-27 Sanofi Aventis Antagonist antibody against epha2 for the treatment of cancer
US20110171191A1 (en) 2008-06-12 2011-07-14 Syntaxin Limited Suppression of neuroendocrine diseases
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872484A (en) * 1956-05-21 1959-02-03 American Cyanamid Co Preparation of tetraalkyl-isothioureas
US4431635A (en) * 1979-06-13 1984-02-14 Coy David Howard LH-RH Antagonists
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
US4504414A (en) * 1983-03-28 1985-03-12 Board Of Regents, The University Of Texas System Synthetic pyridyl-alanyl decapeptides having antiovulatory activity
US4530920A (en) * 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
US4652550A (en) * 1984-05-21 1987-03-24 The Salk Institute For Biological Studies GnRH antagonists VII
IL74827A (en) * 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
US4647653A (en) * 1984-08-23 1987-03-03 Tulane Educational Fund Therapeutic peptides
US4565804A (en) * 1984-09-07 1986-01-21 The Salk Institute For Biological Studies GnRH Antagonists VI
ZA862570B (en) * 1985-04-09 1986-12-30 Univ Tulane Therapeutic decapeptides
AU5638886A (en) * 1985-04-19 1986-10-23 Syntex (U.S.A.) Inc. Contraceptive methods for dogs using the decapeptide lhrh
EP0225746A3 (de) * 1985-11-14 1989-12-20 The Administrators of The Tulane Educational Fund Therapeutische Dekapeptide
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4851385A (en) * 1987-07-15 1989-07-25 Indiana University Foundation LHRH antagonist analogs having low histamine-release activity
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
DE68928278T2 (de) * 1988-02-10 1998-03-12 Tap Pharmaceuticals Inc Lhrh-analog
US5300492A (en) * 1988-02-10 1994-04-05 Tap Pharmaceuticals LHRH analogs
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists

Also Published As

Publication number Publication date
CA2219263A1 (en) 1996-10-31
JPH11504335A (ja) 1999-04-20
AU5667096A (en) 1996-11-18
ES2191753T3 (es) 2003-09-16
DE69626507D1 (de) 2003-04-10
US5656727A (en) 1997-08-12
WO1996033729A1 (en) 1996-10-31
EP0822827A1 (de) 1998-02-11
EP0822827A4 (de) 2001-07-11
DE69626507T2 (de) 2003-11-13
AU703400B2 (en) 1999-03-25
PT822827E (pt) 2003-07-31
EP0822827B1 (de) 2003-03-05

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