DE69621459D1 - Reagens und verfahren zur differentiellen bestimmung von leukozyten im blut - Google Patents

Reagens und verfahren zur differentiellen bestimmung von leukozyten im blut

Info

Publication number
DE69621459D1
DE69621459D1 DE69621459T DE69621459T DE69621459D1 DE 69621459 D1 DE69621459 D1 DE 69621459D1 DE 69621459 T DE69621459 T DE 69621459T DE 69621459 T DE69621459 T DE 69621459T DE 69621459 D1 DE69621459 D1 DE 69621459D1
Authority
DE
Germany
Prior art keywords
leucocytes
reagents
blood
differential determination
differential
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69621459T
Other languages
English (en)
Other versions
DE69621459T2 (de
Inventor
Yi Li
Carole Young
C Veulens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Coulter International Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter International Corp filed Critical Coulter International Corp
Publication of DE69621459D1 publication Critical patent/DE69621459D1/de
Application granted granted Critical
Publication of DE69621459T2 publication Critical patent/DE69621459T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69621459T 1995-12-18 1996-12-12 Reagens und verfahren zur differentiellen bestimmung von leukozyten im blut Expired - Fee Related DE69621459T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/573,768 US5817518A (en) 1995-12-18 1995-12-18 Reagent and method for differential determination of leukocytes in blood
PCT/US1996/019560 WO1997022878A2 (en) 1995-12-18 1996-12-12 Reagent and method for differential determination of leukocytes in blood

Publications (2)

Publication Number Publication Date
DE69621459D1 true DE69621459D1 (de) 2002-07-04
DE69621459T2 DE69621459T2 (de) 2003-01-09

Family

ID=24293323

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621459T Expired - Fee Related DE69621459T2 (de) 1995-12-18 1996-12-12 Reagens und verfahren zur differentiellen bestimmung von leukozyten im blut

Country Status (5)

Country Link
US (1) US5817518A (de)
EP (1) EP0874988B1 (de)
JP (1) JP3717939B2 (de)
DE (1) DE69621459T2 (de)
WO (1) WO1997022878A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509192B1 (en) * 1992-02-24 2003-01-21 Coulter International Corp. Quality control method
US5843608A (en) * 1995-06-08 1998-12-01 Coulter International Corp. Reagent and method for differential determination of leukocytes in blood
US5830701A (en) * 1997-03-28 1998-11-03 Tao Medical Electronics Co., Ltd. Method of detecting hematopoietic progenitor cells
US6210969B1 (en) 1999-04-28 2001-04-03 Coulter International Corp. Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood
US6214625B1 (en) 1999-04-28 2001-04-10 Coulter International Corp. Composition and method for differentiation of basophils and eosinophils in blood
WO2003012429A1 (en) 2001-07-27 2003-02-13 Coulter International Corp. Method for measurement of nucleated red blood cells
US6573102B2 (en) * 2001-07-27 2003-06-03 Coulter International Corp. Lytic reagent composition for determination of nucleated blood cells
US6472215B1 (en) * 2001-07-27 2002-10-29 Coulter International Corp. Method of analyzing nucleated red blood cells in a blood sample
EP1422509A1 (de) * 2002-11-01 2004-05-26 Streck Laboratories, Inc. Lysierungsreagenz und Verfahren zum Lysieren von Roten Blutkörperchen für die Hämatologie
US6869798B2 (en) * 2003-04-17 2005-03-22 Clinical Diagnostics Solutions, Inc. Lytic reagent composition for leukocyte differential analysis
US7658959B2 (en) 2003-06-12 2010-02-09 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
US7090882B2 (en) 2003-06-12 2006-08-15 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
US7588696B2 (en) 2003-06-12 2009-09-15 Cargill, Incorporated Antimicrobial water softener salt and solutions
US7883732B2 (en) 2003-06-12 2011-02-08 Cargill, Incorporated Antimicrobial salt solutions for cheese processing applications
JP2005043365A (ja) * 2003-07-21 2005-02-17 Bayer Corp 白血球を減少させた血液バンク製剤における残留白血球を分析するための試薬組成物
US8486472B2 (en) 2006-01-18 2013-07-16 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
CN101078720B (zh) * 2006-05-22 2010-12-01 深圳迈瑞生物医疗电子股份有限公司 一种改进的用于对白细胞进行分类的试剂及方法
CN101078721B (zh) * 2006-05-23 2010-12-22 深圳迈瑞生物医疗电子股份有限公司 对白细胞进行分类的试剂及方法
ES2336622T3 (es) 2006-06-06 2010-04-14 F. Hoffmann-La Roche Ag Recipiente de recogida de sangre total lista para usar.
CN101467036B (zh) 2006-06-06 2013-06-19 霍夫曼-拉罗奇有限公司 全血样品的差异溶血
US7449337B2 (en) * 2007-01-24 2008-11-11 Idexx Laboratories, Inc. Lytic reagent and method for leukocytes differential in whole blood
CA2677123A1 (en) * 2007-02-02 2008-08-07 Canadian Blood Services Method of detecting bacterial contamination using dynamic light scattering
CN101349644B (zh) 2007-07-20 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 一种白细胞分类试剂和其使用方法
US8102161B2 (en) * 2007-09-25 2012-01-24 Tdk Corporation Stable output in a switching power supply by smoothing the output of the secondary coil
CN101475754A (zh) 2008-01-04 2009-07-08 深圳迈瑞生物医疗电子股份有限公司 不对称菁类荧光染料,组合物及在生物样品染色中的用途
CN104965068B (zh) * 2008-05-09 2017-12-08 希森美康株式会社 血液分析装置，血液分析方法及溶血剂
CN101602762B (zh) 2008-06-10 2013-10-16 深圳迈瑞生物医疗电子股份有限公司 不对称菁类化合物、其制备方法及应用
CN101726579B (zh) 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
CN101750274B (zh) 2008-12-17 2014-06-25 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法
CN101988082B (zh) 2009-07-31 2015-04-08 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
WO2011143044A2 (en) * 2010-05-10 2011-11-17 Idexx Laboratories, Inc. A lytic reagent system for flow cytometric analysis of leukocytes based on morphology or immunophenotypes
US9091677B2 (en) 2010-08-09 2015-07-28 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2656508A (en) * 1949-08-27 1953-10-20 Wallace H Coulter Means for counting particles suspended in a fluid
US4298836A (en) * 1979-11-23 1981-11-03 Coulter Electronics, Inc. Particle shape determination
DE3004611A1 (de) * 1980-02-08 1981-08-13 Hoechst Ag, 6000 Frankfurt Hochkonzentrierte fuellstoffslurries
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US5155044A (en) * 1987-03-13 1992-10-13 Coulter Electronics, Inc. Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples
KR970007077B1 (ko) * 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 광산란 기술을 이용한 다중-부분식별 분석 방법
US5389549A (en) * 1987-05-29 1995-02-14 Toa Medical Electronics Co., Ltd. Method for classifying leukocytes and a reagent used therefor
JP2619900B2 (ja) * 1988-01-27 1997-06-11 東亜医用電子株式会社 血液中の白血球およびヘモグロビンの測定用試薬および方法
CA2016699C (en) * 1989-05-15 2003-11-18 Paul N. Marshall Lytic agents and uses thereof
FR2654744B1 (fr) * 1989-11-20 1992-03-13 Abx Sa Reactif et methode d'utilisation de celui-ci pour la determination automatique en cytometrie de flux d'au moins une sous-population leucocytaire a partir du sang total.
FR2658300B1 (fr) * 1990-02-13 1992-05-29 Abx Sa Reactif et methode d'utilisation de celui-ci pour la numeration automatique des leucocytes basophiles du sang en appareils de mesure par variation de resistivite.
DE69327775T2 (de) * 1992-11-19 2000-06-21 Sysmex Corp Verfahren zur Vorbehandlung für Blutanalyse
JP3467310B2 (ja) * 1994-04-21 2003-11-17 シスメックス株式会社 白血球分析用試薬及び白血球の分類方法
US5639630A (en) * 1995-05-16 1997-06-17 Bayer Corporation Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes
FR2735579B1 (fr) * 1995-06-13 1997-09-19 Hycel Groupe Lisabio Procede de discrimination et d'isolement de sous-populations de leucocytes a partir d'echantillons sanguins par traitement par du polyoxyethylene 9-lauryl ether, et reactif pour sa mise en oeuvre

Also Published As

Publication number Publication date
JP2000502187A (ja) 2000-02-22
EP0874988A2 (de) 1998-11-04
WO1997022878A2 (en) 1997-06-26
US5817518A (en) 1998-10-06
DE69621459T2 (de) 2003-01-09
JP3717939B2 (ja) 2005-11-16
WO1997022878A3 (en) 1997-07-24
WO1997022878A8 (en) 2002-10-10
EP0874988B1 (de) 2002-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee