DE69620437T2 - Verfahren zur herstellung von optisch aktivem 2-substituiertem tetrahydropyran-4-on - Google Patents

Verfahren zur herstellung von optisch aktivem 2-substituiertem tetrahydropyran-4-on

Info

Publication number
DE69620437T2
DE69620437T2 DE69620437T DE69620437T DE69620437T2 DE 69620437 T2 DE69620437 T2 DE 69620437T2 DE 69620437 T DE69620437 T DE 69620437T DE 69620437 T DE69620437 T DE 69620437T DE 69620437 T2 DE69620437 T2 DE 69620437T2
Authority
DE
Germany
Prior art keywords
pct
optically active
date
substituted tetrahydropyran
producing optically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69620437T
Other languages
English (en)
Other versions
DE69620437D1 (de
Inventor
Antony Holt
Richard Rigby
David Waterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avecia Ltd
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Ltd filed Critical Avecia Ltd
Publication of DE69620437D1 publication Critical patent/DE69620437D1/de
Application granted granted Critical
Publication of DE69620437T2 publication Critical patent/DE69620437T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69620437T 1995-11-23 1996-11-19 Verfahren zur herstellung von optisch aktivem 2-substituiertem tetrahydropyran-4-on Expired - Fee Related DE69620437T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9523924.0A GB9523924D0 (en) 1995-11-23 1995-11-23 Production of optically active 2-substituted tetrahydropyran-4-ones
PCT/GB1996/002838 WO1997019185A1 (en) 1995-11-23 1996-11-19 Production of optically active 2-substituted tetrahydropyran-4-ones

Publications (2)

Publication Number Publication Date
DE69620437D1 DE69620437D1 (de) 2002-05-08
DE69620437T2 true DE69620437T2 (de) 2002-11-07

Family

ID=10784307

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69620437T Expired - Fee Related DE69620437T2 (de) 1995-11-23 1996-11-19 Verfahren zur herstellung von optisch aktivem 2-substituiertem tetrahydropyran-4-on

Country Status (12)

Country Link
US (1) US5962282A (de)
EP (1) EP0862646B1 (de)
JP (1) JP2000500344A (de)
AT (1) ATE215603T1 (de)
AU (1) AU7583696A (de)
CA (1) CA2238172A1 (de)
DE (1) DE69620437T2 (de)
DK (1) DK0862646T3 (de)
ES (1) ES2171740T3 (de)
GB (1) GB9523924D0 (de)
PT (1) PT862646E (de)
WO (1) WO1997019185A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258574B1 (en) * 1995-11-23 2001-07-10 Zeneca Limited Production of optically active 2-substituted tetrahydropyran-4-ones
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
EP1375493A1 (de) 2002-06-17 2004-01-02 Dsm N.V. Verfahren zur Herstellung von Dioxanessigsäureester

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3049403B2 (ja) * 1991-11-01 2000-06-05 チッソ株式会社 光学活性トランス−２−アリール−１−シクロヘキサノール誘導体およびその製造法
CA2118796A1 (en) * 1991-09-20 1993-04-01 John Crosby Pyranones
US5527916A (en) * 1991-09-20 1996-06-18 Zeneca Limited Pyranones

Also Published As

Publication number Publication date
DE69620437D1 (de) 2002-05-08
DK0862646T3 (da) 2002-07-22
WO1997019185A1 (en) 1997-05-29
EP0862646A1 (de) 1998-09-09
EP0862646B1 (de) 2002-04-03
JP2000500344A (ja) 2000-01-18
AU7583696A (en) 1997-06-11
PT862646E (pt) 2002-09-30
ES2171740T3 (es) 2002-09-16
ATE215603T1 (de) 2002-04-15
CA2238172A1 (en) 1997-05-29
GB9523924D0 (en) 1996-01-24
US5962282A (en) 1999-10-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee