DE69618080T2 - Epstein-Barr Viruspeptide, und Antikörper gegen diese Peptide - Google Patents

Epstein-Barr Viruspeptide, und Antikörper gegen diese Peptide

Info

Publication number
DE69618080T2
DE69618080T2 DE69618080T DE69618080T DE69618080T2 DE 69618080 T2 DE69618080 T2 DE 69618080T2 DE 69618080 T DE69618080 T DE 69618080T DE 69618080 T DE69618080 T DE 69618080T DE 69618080 T2 DE69618080 T2 DE 69618080T2
Authority
DE
Germany
Prior art keywords
peptides
ebv
epstein
barr virus
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69618080T
Other languages
English (en)
Other versions
DE69618080D1 (de
Inventor
Jaap Michiel Middeldorp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux BV
Original Assignee
Organon Teknika BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Teknika BV filed Critical Organon Teknika BV
Application granted granted Critical
Publication of DE69618080D1 publication Critical patent/DE69618080D1/de
Publication of DE69618080T2 publication Critical patent/DE69618080T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16211Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20Immunohistochemistry assay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811Peptides or proteins is immobilized on, or in, an inorganic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69618080T 1995-06-06 1996-05-28 Epstein-Barr Viruspeptide, und Antikörper gegen diese Peptide Expired - Lifetime DE69618080T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95201486 1995-06-06

Publications (2)

Publication Number Publication Date
DE69618080D1 DE69618080D1 (de) 2002-01-31
DE69618080T2 true DE69618080T2 (de) 2002-06-13

Family

ID=8220358

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69618080T Expired - Lifetime DE69618080T2 (de) 1995-06-06 1996-05-28 Epstein-Barr Viruspeptide, und Antikörper gegen diese Peptide

Country Status (13)

Country Link
US (2) US5843405A (de)
EP (1) EP0747481B1 (de)
JP (2) JP4319703B2 (de)
KR (1) KR100523972B1 (de)
AT (1) ATE211172T1 (de)
AU (1) AU707301B2 (de)
CA (1) CA2178057C (de)
DE (1) DE69618080T2 (de)
DK (1) DK0747481T3 (de)
ES (1) ES2170195T3 (de)
HK (1) HK1001164A1 (de)
PT (1) PT747481E (de)
ZA (1) ZA964683B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824912B1 (fr) * 2001-05-18 2004-10-29 Jacques Gregoire Dispositif de kit elisa, base sur un antigene : proteines m dbp, du virus ebv, particulierement destine au diagnostic serologique du cancer npc, et le procede de preparation de cette proteine
JP2005060314A (ja) * 2003-08-13 2005-03-10 Masao Tanihara 化粧料
JP5112076B2 (ja) 2004-11-15 2013-01-09 バイオセンス・ウエブスター・インコーポレーテツド 微細加工温度センサを備えたカテーテル
EP2101177A1 (de) * 2008-03-10 2009-09-16 Universite Joseph Fourier Verwendung eines synthetischen Peptids aus dem ZEBRA-Protein für die in-vitro-Diagnose von Epstein-Barr-Virus (EBV)-Reaktivierung
WO2013088114A1 (en) 2011-12-12 2013-06-20 Cell Medica Limited Process of expanding t cells
GB201121308D0 (en) 2011-12-12 2012-01-25 Cell Medica Ltd Process
DK3591047T3 (da) 2012-02-09 2022-10-24 Baylor College Medicine Peptidblandinger til generering af multivirale CTL¿er med bred specificitet
JP6999941B2 (ja) 2015-09-18 2022-02-10 ベイラー カレッジ オブ メディスン 病原体からの免疫原性抗原同定および臨床的有効性との相関
US10772914B1 (en) * 2019-04-18 2020-09-15 Baylor College Of Medicine EBV-specific immune cells
CN111574621B (zh) * 2020-04-30 2022-03-29 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一种中和eb病毒的单克隆抗体及其应用
CN111690056B (zh) * 2020-04-30 2021-12-21 清华大学 一种中和eb病毒的单克隆抗体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61257188A (ja) * 1984-08-23 1986-11-14 ハンス ヨツト ヴオルフ Ebvゲノムのdna配列、組換えdna分子、ならびにebv関連抗原および該抗原を含有する診断用組成物および製剤組成物の製造法
DE3583564D1 (de) * 1984-08-23 1991-08-29 Hans Joachim Wolf Dna-sequenzen des ebv-genoms, rekombinante dna-molekuele, verfahren zur herstellung von ebv-verwandten antigenen sowie diagnostische zusammensetzungen und pharmazeutische zusammensetzungen, die die genannten antigene enthalten.
US5256768A (en) * 1985-12-13 1993-10-26 The Johns Hopkins University Expression of antigenic Epstein-Barr virus polypeptides in bacteria and their use in diagnostics
US4761470A (en) * 1985-12-16 1988-08-02 Merck & Co., Inc. Immunogenic synthetic peptide capable of eliciting herpes simplex virus neutralizing antibody
US5087557A (en) * 1986-06-23 1992-02-11 Genetic Systems Corporation Human monoclonal antibody to lymphadenopathy-associated virus
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse

Also Published As

Publication number Publication date
JP2008188017A (ja) 2008-08-21
DE69618080D1 (de) 2002-01-31
US5843405A (en) 1998-12-01
US6143865A (en) 2000-11-07
JPH0925295A (ja) 1997-01-28
HK1001164A1 (en) 1998-05-29
ZA964683B (en) 1997-01-07
JP4319703B2 (ja) 2009-08-26
PT747481E (pt) 2002-05-31
EP0747481B1 (de) 2001-12-19
AU5479396A (en) 1996-12-19
CA2178057C (en) 2010-08-03
ES2170195T3 (es) 2002-08-01
AU707301B2 (en) 1999-07-08
ATE211172T1 (de) 2002-01-15
CA2178057A1 (en) 1996-12-07
KR100523972B1 (ko) 2006-04-14
DK0747481T3 (da) 2002-04-08
JP4612071B2 (ja) 2011-01-12
EP0747481A1 (de) 1996-12-11

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