DE69615201T2 - Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden - Google Patents

Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden

Info

Publication number
DE69615201T2
DE69615201T2 DE69615201T DE69615201T DE69615201T2 DE 69615201 T2 DE69615201 T2 DE 69615201T2 DE 69615201 T DE69615201 T DE 69615201T DE 69615201 T DE69615201 T DE 69615201T DE 69615201 T2 DE69615201 T2 DE 69615201T2
Authority
DE
Germany
Prior art keywords
regulatory sequences
genre
tire
cells
specifically expressed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69615201T
Other languages
English (en)
Other versions
DE69615201D1 (de
Inventor
David Klatzmann
Patrick Salmon
Olivier Boyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Pierre et Marie Curie Paris 6
Original Assignee
Universite Pierre et Marie Curie Paris 6
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Pierre et Marie Curie Paris 6 filed Critical Universite Pierre et Marie Curie Paris 6
Application granted granted Critical
Publication of DE69615201D1 publication Critical patent/DE69615201D1/de
Publication of DE69615201T2 publication Critical patent/DE69615201T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C12N9/1211—Thymidine kinase (2.7.1.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69615201T 1995-07-17 1996-07-17 Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden Expired - Lifetime DE69615201T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9508616A FR2736931B1 (fr) 1995-07-17 1995-07-17 Sequences regulatrices issues du gene cd4 et a expression specifique dans les lymphocytes t matures
PCT/FR1996/001122 WO1997004118A1 (fr) 1995-07-17 1996-07-17 Sequences regulatrices issues du gene cd4 et a expression specifique dans les lymphocytes t matures

Publications (2)

Publication Number Publication Date
DE69615201D1 DE69615201D1 (de) 2001-10-18
DE69615201T2 true DE69615201T2 (de) 2002-05-02

Family

ID=9481044

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69615201T Expired - Lifetime DE69615201T2 (de) 1995-07-17 1996-07-17 Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden

Country Status (9)

Country Link
US (1) US6333171B1 (de)
EP (1) EP0839206B1 (de)
JP (1) JPH11509415A (de)
AT (1) ATE205538T1 (de)
CA (1) CA2227035A1 (de)
DE (1) DE69615201T2 (de)
ES (1) ES2164907T3 (de)
FR (1) FR2736931B1 (de)
WO (1) WO1997004118A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9807935D0 (en) 1998-04-14 1998-06-10 Univ Edinburgh Lineage specific cells and progenitor cells
US7462485B2 (en) * 2005-10-07 2008-12-09 Glaser Lawrence F Modified erythrocytes and uses thereof
WO2009130208A1 (en) * 2008-04-22 2009-10-29 Vib Vzw Liver-specific nucleic acid regulatory elements and methods and use thereof
JP6273653B2 (ja) * 2015-10-23 2018-02-07 学校法人北里研究所 大腸炎又は大腸癌モデル非ヒト動物及びその利用
KR20220030205A (ko) * 2019-02-08 2022-03-10 디앤에이 투포인토 인크. 면역 세포의 트랜스포존 기반 변형

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008844A1 (fr) 1991-10-30 1993-05-13 Universite Pierre Et Marie Curie (Paris Vi) Cellules transformees pour la prevention ou le traitement de maladies induites par des virus, notamment retrovirus pathogenes
FR2683226B1 (fr) 1991-10-30 1995-06-09 Univ Paris Curie Cellules piegees a l'egard d'antigenes provoquant le dysfonctionnement du systeme immunitaire, medicaments pour la prevention ou le traitement de maladies induites par ces dysfonctionnements.
FR2699191B1 (fr) 1992-12-16 1995-02-10 Univ Paris Curie Nouveaux vecteurs rétroviraux, lignées cellulaires les contenant, et leur utilisation dans le traitement des tumeurs.
FR2716459B1 (fr) 1994-02-22 1996-05-10 Univ Paris Curie Système hôte-vecteur utilisable en thérapie génique.
JPH10503641A (ja) * 1994-05-02 1998-04-07 ユニバーシティ オブ ワシントン チミジンキナーゼ変異体

Also Published As

Publication number Publication date
ATE205538T1 (de) 2001-09-15
CA2227035A1 (fr) 1997-02-06
US6333171B1 (en) 2001-12-25
ES2164907T3 (es) 2002-03-01
EP0839206B1 (de) 2001-09-12
JPH11509415A (ja) 1999-08-24
WO1997004118A1 (fr) 1997-02-06
FR2736931B1 (fr) 1997-09-19
FR2736931A1 (fr) 1997-01-24
EP0839206A1 (de) 1998-05-06
DE69615201D1 (de) 2001-10-18

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