DE69613783D1 - 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen - Google Patents

4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen

Info

Publication number
DE69613783D1
DE69613783D1 DE69613783T DE69613783T DE69613783D1 DE 69613783 D1 DE69613783 D1 DE 69613783D1 DE 69613783 T DE69613783 T DE 69613783T DE 69613783 T DE69613783 T DE 69613783T DE 69613783 D1 DE69613783 D1 DE 69613783D1
Authority
DE
Germany
Prior art keywords
pct
chromen
benzisoxazolyl
psychosis
schizophrenia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69613783T
Other languages
English (en)
Other versions
DE69613783T2 (de
Inventor
Rafael Foguet
Lluis Anglada
Jordi Bolos
A Ortiz
Aurelio Sacristan
M Castello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9500737A external-priority patent/ES2101646B1/es
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Publication of DE69613783D1 publication Critical patent/DE69613783D1/de
Application granted granted Critical
Publication of DE69613783T2 publication Critical patent/DE69613783T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69613783T 1995-04-12 1996-04-11 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen Expired - Lifetime DE69613783T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES9500737A ES2101646B1 (es) 1995-04-12 1995-04-12 Nuevo compuesto derivado del cromeno.
ES9600323A ES2103237B1 (es) 1995-04-12 1996-02-09 Nuevo compuesto derivado del cromeno.
PCT/EP1996/001551 WO1996032389A1 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety

Publications (2)

Publication Number Publication Date
DE69613783D1 true DE69613783D1 (de) 2001-08-16
DE69613783T2 DE69613783T2 (de) 2002-04-25

Family

ID=26154880

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69613783T Expired - Lifetime DE69613783T2 (de) 1995-04-12 1996-04-11 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen

Country Status (15)

Country Link
US (1) US5736558A (de)
EP (1) EP0765323B1 (de)
JP (1) JP3916662B2 (de)
AT (1) ATE203022T1 (de)
AU (1) AU696494B2 (de)
CA (1) CA2192596C (de)
DE (1) DE69613783T2 (de)
DK (1) DK0765323T3 (de)
GR (1) GR3036825T3 (de)
IL (1) IL117646A (de)
MX (1) MX9601163A (de)
NO (1) NO307517B1 (de)
NZ (1) NZ306447A (de)
PT (1) PT765323E (de)
WO (1) WO1996032389A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2144355B1 (es) * 1997-12-30 2001-01-01 Ferrer Int Compuestos derivados del cromeno.
AU7547100A (en) * 1999-09-09 2001-04-10 Egis Gyogyszergyar Rt. Alkylpiperidi nylbenzo [d] isoxazole derivatives having psychotropic activity, pharmaceutical compositions containing the same, and a process for the preparation of the active ingredient
HU225955B1 (en) * 2001-07-26 2008-01-28 Egis Gyogyszergyar Nyilvanosan Novel 2h-pyridazin-3-one derivatives, process for their preparation, their use and pharmaceutical compositions containing them
MX2007002384A (es) 2004-09-30 2007-05-11 Neurosearch As Nuevos derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina.
CN103694233B (zh) * 2013-12-10 2016-08-17 沈阳药科大学 苯并异噁唑类化合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4678787A (en) * 1985-01-30 1987-07-07 Warner-Lambert Company 4H-1-benzopyran-4-ones and their sulfur containing analogs
FR2654104B1 (fr) * 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
IL112764A0 (en) * 1994-03-18 1995-05-26 Ferrer Int New chromene derivatives

Also Published As

Publication number Publication date
AU696494B2 (en) 1998-09-10
WO1996032389A1 (en) 1996-10-17
IL117646A (en) 2000-06-01
NZ306447A (en) 1997-06-24
DE69613783T2 (de) 2002-04-25
NO307517B1 (no) 2000-04-17
CA2192596A1 (en) 1996-10-17
NO965300L (no) 1996-12-11
US5736558A (en) 1998-04-07
ATE203022T1 (de) 2001-07-15
MX9601163A (es) 1997-02-28
GR3036825T3 (en) 2002-01-31
JP3916662B2 (ja) 2007-05-16
CA2192596C (en) 2004-06-22
DK0765323T3 (da) 2001-09-24
NO965300D0 (no) 1996-12-11
EP0765323A1 (de) 1997-04-02
JPH10501557A (ja) 1998-02-10
PT765323E (pt) 2001-12-28
EP0765323B1 (de) 2001-07-11
IL117646A0 (en) 1996-07-23
AU5500496A (en) 1996-10-30

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DE69613783T2 (de) 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen
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Legal Events

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