DE69611373D1 - Bestimmung eines analyten in einer flüssigkeit - Google Patents

Bestimmung eines analyten in einer flüssigkeit

Info

Publication number
DE69611373D1
DE69611373D1 DE69611373T DE69611373T DE69611373D1 DE 69611373 D1 DE69611373 D1 DE 69611373D1 DE 69611373 T DE69611373 T DE 69611373T DE 69611373 T DE69611373 T DE 69611373T DE 69611373 D1 DE69611373 D1 DE 69611373D1
Authority
DE
Germany
Prior art keywords
immobilized
probe
members
recognition pair
metal plates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69611373T
Other languages
English (en)
Other versions
DE69611373T2 (de
Inventor
Itamar Willner
Shlomo Levi
Yael Cohen
Eugenii Katz
Arie Dagan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Biosensor Applications Sweden AB
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of DE69611373D1 publication Critical patent/DE69611373D1/de
Application granted granted Critical
Publication of DE69611373T2 publication Critical patent/DE69611373T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
DE69611373T 1995-07-21 1996-07-16 Bestimmung eines analyten in einer flüssigkeit Expired - Lifetime DE69611373T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11469295A IL114692A (en) 1995-07-21 1995-07-21 Determination of an analyte in a liquid medium
PCT/IL1996/000049 WO1997004314A2 (en) 1995-07-21 1996-07-16 Determination of an analyte in a liquid medium

Publications (2)

Publication Number Publication Date
DE69611373D1 true DE69611373D1 (de) 2001-02-01
DE69611373T2 DE69611373T2 (de) 2001-08-16

Family

ID=11067798

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69611373T Expired - Lifetime DE69611373T2 (de) 1995-07-21 1996-07-16 Bestimmung eines analyten in einer flüssigkeit

Country Status (11)

Country Link
US (1) US6630309B2 (de)
EP (1) EP0843816B1 (de)
JP (1) JP3895379B2 (de)
AT (1) ATE198376T1 (de)
AU (1) AU6317896A (de)
CA (1) CA2227281C (de)
DE (1) DE69611373T2 (de)
DK (1) DK0843816T3 (de)
ES (1) ES2155190T3 (de)
IL (1) IL114692A (de)
WO (1) WO1997004314A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69724249T2 (de) * 1996-05-23 2004-06-09 Inverness Medical Switzerland Gmbh Verbesserungen in oder in bezug auf spezifische bindungsassays
SE9604575D0 (sv) * 1996-12-12 1996-12-12 Biacore Ab Method and system for analyte determination
IL120445A0 (en) * 1997-03-13 1997-07-13 Yissum Res Dev Co Biosensor for cells
SG81232A1 (en) * 1998-06-05 2001-06-19 Inst Materials Research & Eng Piezoelectric immunosensor
SE512994C2 (sv) * 1998-09-24 2000-06-12 Biosensor Applic Sweden Ab Biosensorcellanordning och dess användning
IL128212A (en) 1999-01-25 2004-06-20 Biosensor Applic Sweden Ab Detection of small molecules by use of a piezoelectric sensor
US7763475B2 (en) * 1999-04-22 2010-07-27 Inverness Medical Switzerland Gmbh Measurement and use of molecular interactions
GB9909308D0 (en) * 1999-04-22 1999-06-16 Univ Cambridge Tech Measurement and use of molecular interactions
SG93209A1 (en) * 1999-07-05 2002-12-17 Inst Of Molecular Agrobiology A novel immuno-diagnostic test method for veterinary disease
JP2004309416A (ja) * 2003-04-10 2004-11-04 Sony Corp センサ装置、センシング方法、生体物質のセンサ装置、生体物質のセンシング方法、分泌物のセンサ装置、分泌物のセンシング方法、感情センサ装置および感情センシング方法
US20050148065A1 (en) 2003-12-30 2005-07-07 Intel Corporation Biosensor utilizing a resonator having a functionalized surface
US8354066B2 (en) * 2004-03-24 2013-01-15 Technion Research & Development Foundation Ltd. Artificial receptors
EP1730531B1 (de) * 2004-03-24 2014-01-15 Technion Research and Development Foundation, Limited Elektrode
US7695681B2 (en) * 2005-03-31 2010-04-13 Intel Corporation Miniature chemical analysis system
US20080261323A1 (en) * 2005-09-06 2008-10-23 Dermot Diamond Photo-Swichable Surfaces with Controllable Physico-Chemical Properties
KR100722844B1 (ko) * 2006-05-30 2007-05-31 이화여자대학교 산학협력단 단일 측정 시스템에서 효소의 활성 및 양을 인 시투측정하기 위한 방법 및 키트
US8512947B2 (en) 2007-02-16 2013-08-20 Drexel University Detection of nucleic acids using a cantilever sensor
US7892759B2 (en) * 2007-02-16 2011-02-22 Drexel University Enhanced sensitivity of a cantilever sensor via specific bindings
JP5276655B2 (ja) * 2007-06-01 2013-08-28 アトノミックス アクティーゼルスカブ 標的検体の検出用のナノ粒子を用いた生体表面弾性波（ｓａｗ）共振器増幅
WO2010055959A1 (en) * 2008-11-11 2010-05-20 Korea Institute Of Science And Technology System for detecting biomolecule wi th high sensitivity using micro-cant i lever
US8349611B2 (en) * 2009-02-17 2013-01-08 Leversense Llc Resonant sensors and methods of use thereof for the determination of analytes
DK2630479T3 (da) 2010-10-20 2020-07-20 Qorvo Us Inc Anordning og fremgangsmåde til måling af bindingskinetik og koncentration med en resonanssensor
WO2016194879A1 (ja) * 2015-05-29 2016-12-08 京セラ株式会社 検出方法、および検出装置
US9464487B1 (en) 2015-07-22 2016-10-11 William Harrison Zurn Drill bit and cylinder body device, assemblies, systems and methods
IT201900007725A1 (it) * 2019-05-31 2020-12-01 Eye Pharma Spa Metodo per la diagnosi precoce del glaucoma

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242096A (en) 1977-11-14 1980-12-30 Minnesota Mining And Manufacturing Company Immunoassay for antigens
US4314821A (en) 1979-04-09 1982-02-09 Minnesota Mining And Manufacturing Company Sandwich immunoassay using piezoelectric oscillator
US4236893A (en) 1979-04-09 1980-12-02 Minnesota Mining And Manufacturing Company Method for the assay of classes of antigen-specific antibodies
US4735906A (en) 1984-11-28 1988-04-05 Texas A&M University Sensor having piezoelectric crystal for microgravimetric immunoassays
US5595908A (en) * 1985-09-26 1997-01-21 University Of Southern Mississipi Piezoelectric device for detection of polynucleotide hybridization
US5192507A (en) * 1987-06-05 1993-03-09 Arthur D. Little, Inc. Receptor-based biosensors
US4999284A (en) * 1988-04-06 1991-03-12 E. I. Du Pont De Nemours And Company Enzymatically amplified piezoelectric specific binding assay
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
US5235238A (en) * 1989-08-10 1993-08-10 Dainabot Company, Limited Electrode-separated piezoelectric crystal oscillator and method for measurement using the electrode-separated piezoelectric crystal oscillator
WO1991005261A1 (en) 1989-10-04 1991-04-18 E.I. Du Pont De Nemours And Company Assay method for biological target complexes on the surface of a biosensor
EP0650598B1 (de) * 1992-07-17 1997-04-02 E.I. Du Pont De Nemours And Company Nachweis eines Analyten mittels eines Analyt-sensitiven Polymers
US5552274A (en) * 1992-09-07 1996-09-03 Terumo Kabushiki Kaisha Method for detecting target sequences by oscillation frequency
US5527711A (en) * 1993-12-13 1996-06-18 Hewlett Packard Company Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques
IL108726A (en) * 1994-02-22 1999-12-31 Yissum Res Dev Co Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor
US5583432A (en) * 1994-04-11 1996-12-10 Sci-Nostics Limited Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood
US5705399A (en) * 1994-05-20 1998-01-06 The Cooper Union For Advancement Of Science And Art Sensor and method for detecting predetermined chemical species in solution
US5514501A (en) * 1994-06-07 1996-05-07 The United States Of America As Represented By The Secretary Of Commerce Process for UV-photopatterning of thiolate monolayers self-assembled on gold, silver and other substrates
US5852229A (en) * 1996-05-29 1998-12-22 Kimberly-Clark Worldwide, Inc. Piezoelectric resonator chemical sensing device

Also Published As

Publication number Publication date
AU6317896A (en) 1997-02-18
IL114692A (en) 1999-10-28
CA2227281C (en) 2008-09-23
JP3895379B2 (ja) 2007-03-22
DK0843816T3 (da) 2001-03-26
US6630309B2 (en) 2003-10-07
IL114692A0 (en) 1995-11-27
CA2227281A1 (en) 1997-02-06
ATE198376T1 (de) 2001-01-15
EP0843816B1 (de) 2000-12-27
WO1997004314A2 (en) 1997-02-06
JPH11510247A (ja) 1999-09-07
ES2155190T3 (es) 2001-05-01
US20020028440A1 (en) 2002-03-07
DE69611373T2 (de) 2001-08-16
EP0843816A2 (de) 1998-05-27
WO1997004314A3 (en) 1997-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW

Owner name: BIOSENSOR APPLICATIONS SWEDEN AB, SUNDBYBERG, SE