DE69610331D1 - Neue gylcylanilid-derivate, deren herstellung und deren verwendung zur behandlung von hypercholesterolämie und atherosklerose - Google Patents

Neue gylcylanilid-derivate, deren herstellung und deren verwendung zur behandlung von hypercholesterolämie und atherosklerose

Info

Publication number
DE69610331D1
DE69610331D1 DE69610331T DE69610331T DE69610331D1 DE 69610331 D1 DE69610331 D1 DE 69610331D1 DE 69610331 T DE69610331 T DE 69610331T DE 69610331 T DE69610331 T DE 69610331T DE 69610331 D1 DE69610331 D1 DE 69610331D1
Authority
DE
Germany
Prior art keywords
derivatives
pct
atherosclerosis
treatment
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69610331T
Other languages
English (en)
Other versions
DE69610331T2 (de
Inventor
Jean-Francois Patoiseau
Jean-Marie Autin
Andre Delhon
Philippe Oms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of DE69610331D1 publication Critical patent/DE69610331D1/de
Application granted granted Critical
Publication of DE69610331T2 publication Critical patent/DE69610331T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69610331T 1995-01-19 1996-01-18 Neue gylcylanilid-derivate, deren herstellung und deren verwendung zur behandlung von hypercholesterolämie und atherosklerose Expired - Fee Related DE69610331T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9500577A FR2729665B1 (fr) 1995-01-19 1995-01-19 Nouveaux derives de glycylanilides, leur preparation et leur application en therapeutique
PCT/FR1996/000081 WO1996022279A1 (fr) 1995-01-19 1996-01-18 Nouveaux derives de glycylanilides, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
DE69610331D1 true DE69610331D1 (de) 2000-10-19
DE69610331T2 DE69610331T2 (de) 2001-04-12

Family

ID=9475280

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69610331T Expired - Fee Related DE69610331T2 (de) 1995-01-19 1996-01-18 Neue gylcylanilid-derivate, deren herstellung und deren verwendung zur behandlung von hypercholesterolämie und atherosklerose

Country Status (14)

Country Link
US (1) US5760087A (de)
EP (1) EP0871611B1 (de)
JP (1) JPH10512562A (de)
AT (1) ATE196289T1 (de)
AU (1) AU707456B2 (de)
CA (1) CA2211342A1 (de)
DE (1) DE69610331T2 (de)
DK (1) DK0871611T3 (de)
ES (1) ES2152009T3 (de)
FR (1) FR2729665B1 (de)
GR (1) GR3035010T3 (de)
NZ (1) NZ300640A (de)
PT (1) PT871611E (de)
WO (1) WO1996022279A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19958121A1 (de) 1999-12-02 2001-06-28 Max Planck Gesellschaft Tyrosin- und tryptophanhaltige Peptide als Antioxidantien

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
WO1992009572A1 (fr) * 1990-11-26 1992-06-11 Taisho Pharmaceutical Co., Ltd. Derive d'anilide
CA2105617A1 (en) * 1992-09-10 1994-03-11 Yoshikazu Iwasawa Substituted acetamide derivatives

Also Published As

Publication number Publication date
JPH10512562A (ja) 1998-12-02
US5760087A (en) 1998-06-02
FR2729665A1 (fr) 1996-07-26
FR2729665B1 (fr) 1997-04-18
GR3035010T3 (en) 2001-03-30
EP0871611B1 (de) 2000-09-13
EP0871611A1 (de) 1998-10-21
PT871611E (pt) 2001-03-30
AU4544096A (en) 1996-08-07
AU707456B2 (en) 1999-07-08
WO1996022279A1 (fr) 1996-07-25
NZ300640A (en) 2000-10-27
DK0871611T3 (da) 2000-12-27
DE69610331T2 (de) 2001-04-12
CA2211342A1 (fr) 1996-07-25
ES2152009T3 (es) 2001-01-16
ATE196289T1 (de) 2000-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee