DE69608862D1 - Verfahren zur Herstellung einer optisch aktiven 2-Hydroxy-4-Arylbuttersäure oder deren Ester und Zwischenprodukt dafür - Google Patents
Verfahren zur Herstellung einer optisch aktiven 2-Hydroxy-4-Arylbuttersäure oder deren Ester und Zwischenprodukt dafürInfo
- Publication number
- DE69608862D1 DE69608862D1 DE69608862T DE69608862T DE69608862D1 DE 69608862 D1 DE69608862 D1 DE 69608862D1 DE 69608862 T DE69608862 T DE 69608862T DE 69608862 T DE69608862 T DE 69608862T DE 69608862 D1 DE69608862 D1 DE 69608862D1
- Authority
- DE
- Germany
- Prior art keywords
- optically active
- acid
- hydroxy
- ester
- arylbutyric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21343195 | 1995-08-22 | ||
JP19264896A JP3915015B2 (ja) | 1995-08-22 | 1996-06-19 | 光学活性2−ヒドロキシ−4−アリール酪酸またはそのエステルの製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69608862D1 true DE69608862D1 (de) | 2000-07-20 |
DE69608862T2 DE69608862T2 (de) | 2001-02-22 |
Family
ID=26507445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69608862T Expired - Fee Related DE69608862T2 (de) | 1995-08-22 | 1996-08-20 | Verfahren zur Herstellung einer optisch aktiven 2-Hydroxy-4-Arylbuttersäure oder deren Ester und Zwischenprodukt dafür |
Country Status (6)
Country | Link |
---|---|
US (3) | US5959139A (de) |
EP (1) | EP0759424B1 (de) |
JP (1) | JP3915015B2 (de) |
AT (1) | ATE193882T1 (de) |
DE (1) | DE69608862T2 (de) |
ES (1) | ES2148689T3 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6508768B1 (en) * | 2000-11-22 | 2003-01-21 | University Of Kansas Medical Center | Ultrasonic elasticity imaging |
GB2375762B (en) | 2001-05-21 | 2003-10-01 | Fermenta Biotech Ltd | Stereospecific synthesis of 2-hydroxy-4-phenyl-butyric acid esters |
WO2004078761A1 (en) * | 2003-03-06 | 2004-09-16 | Ranbaxy Laboratories Limited | Enantiomerically pure cilazapril,process for preparation |
CN100335457C (zh) * | 2005-09-08 | 2007-09-05 | 上海交通大学 | 3-位手性羟基被保护的3,4-二羟基丁酸酯及其制备方法 |
US20090181723A1 (en) * | 2008-01-11 | 2009-07-16 | Koncelik Jr Lawrence J | Apparatus and method for providing audio signal and/or visual indications of cell phone signal quality or signal strength |
CN109929885B (zh) * | 2019-03-06 | 2022-07-15 | 江苏惠利生物科技有限公司 | 一种利用酶膜反应器耦合萃取制备r-2-羟基-4-苯基丁酸乙酯的方法 |
EP4313986A1 (de) | 2021-04-02 | 2024-02-07 | Genentech, Inc. | Verfahren zur herstellung von bicyclischen ketonverbindungen |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US329156A (en) | 1885-10-27 | Combination square and gage | ||
US4785089A (en) | 1985-06-13 | 1988-11-15 | Ciba-Geigy Corporation | Novel sulfonic acid esters and their preparation |
EP0280285B1 (de) * | 1987-02-26 | 1992-09-02 | Merrell Dow Pharmaceuticals Inc. | Verfahren zum Herstellen und Isolieren von Estern der (R)-2-Hydroxyphenylbuttersäure |
GB2210364A (en) * | 1987-09-29 | 1989-06-07 | Ici Plc | Cyclopropane ring-containing tertiary amine derivatives |
US4904822A (en) * | 1988-02-19 | 1990-02-27 | Kuraray Co., Ltd. | Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid |
JP2688528B2 (ja) * | 1989-12-28 | 1997-12-10 | ダイセル化学工業株式会社 | 光学活性2−ヒドロキシ−4−フェニル酪酸アルキルエステルの製造法 |
JPH0418050A (ja) | 1990-05-10 | 1992-01-22 | Yoshitomi Pharmaceut Ind Ltd | (r)―2―ヒドロキシ―4―フェニル―3―ブテン酸の製造法 |
US5225408A (en) | 1991-12-20 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Biphenyl oxadiazinone angiotensin II inhibitors |
SG42936A1 (en) | 1992-04-02 | 1997-10-17 | Ciba Geigy Ag | Ferrocenyl diphosphines as ligands for homogeneous catalysts |
JPH05286890A (ja) * | 1992-04-07 | 1993-11-02 | Toray Ind Inc | 2−ヒドロキシ−4−フェニル酪酸またはそのエステルの製造法 |
AT401513B (de) * | 1994-12-22 | 1996-09-25 | Chemie Linz Gmbh | Verfahren zur herstellung von 2-hydroxy-4-phenylbuttersäure |
-
1996
- 1996-06-19 JP JP19264896A patent/JP3915015B2/ja not_active Expired - Fee Related
- 1996-08-16 US US08/698,730 patent/US5959139A/en not_active Expired - Fee Related
- 1996-08-20 DE DE69608862T patent/DE69608862T2/de not_active Expired - Fee Related
- 1996-08-20 AT AT96306057T patent/ATE193882T1/de not_active IP Right Cessation
- 1996-08-20 EP EP96306057A patent/EP0759424B1/de not_active Expired - Lifetime
- 1996-08-20 ES ES96306057T patent/ES2148689T3/es not_active Expired - Lifetime
-
1999
- 1999-06-29 US US09/340,692 patent/US6087526A/en not_active Expired - Fee Related
-
2000
- 2000-01-05 US US09/477,740 patent/US6258975B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP3915015B2 (ja) | 2007-05-16 |
US6258975B1 (en) | 2001-07-10 |
JPH09118646A (ja) | 1997-05-06 |
US6087526A (en) | 2000-07-11 |
US5959139A (en) | 1999-09-28 |
DE69608862T2 (de) | 2001-02-22 |
EP0759424A1 (de) | 1997-02-26 |
ATE193882T1 (de) | 2000-06-15 |
EP0759424B1 (de) | 2000-06-14 |
ES2148689T3 (es) | 2000-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |