DE69602208T2 - Stabilisierte pharmazeutische zusammensetzungen enthaltend dobutamine - Google Patents
Stabilisierte pharmazeutische zusammensetzungen enthaltend dobutamineInfo
- Publication number
- DE69602208T2 DE69602208T2 DE69602208T DE69602208T DE69602208T2 DE 69602208 T2 DE69602208 T2 DE 69602208T2 DE 69602208 T DE69602208 T DE 69602208T DE 69602208 T DE69602208 T DE 69602208T DE 69602208 T2 DE69602208 T2 DE 69602208T2
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- stabilized pharmaceutical
- dobutamine
- containing dobutamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
- JRWZLRBJNMZMFE-UHFFFAOYSA-N Dobutamine Chemical compound C=1C=C(O)C(O)=CC=1CCNC(C)CCC1=CC=C(O)C=C1 JRWZLRBJNMZMFE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001089 dobutamine Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9512688A FR2740337B1 (fr) | 1995-10-27 | 1995-10-27 | Compositions pharmaceutiques stabilisees contenant un derive ayant une activite adrenergique |
| PCT/FR1996/001671 WO1997015329A1 (fr) | 1995-10-27 | 1996-10-25 | Compositions pharmaceutiques stabilisees contenant de la dobutamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69602208D1 DE69602208D1 (de) | 1999-05-27 |
| DE69602208T2 true DE69602208T2 (de) | 1999-09-02 |
Family
ID=9483984
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69602208T Revoked DE69602208T2 (de) | 1995-10-27 | 1996-10-25 | Stabilisierte pharmazeutische zusammensetzungen enthaltend dobutamine |
| DE0859635T Pending DE859635T1 (de) | 1995-10-27 | 1996-10-25 | Stabilisierte pharmazeutische zusammensetzungen enthaltend dobutamine |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE0859635T Pending DE859635T1 (de) | 1995-10-27 | 1996-10-25 | Stabilisierte pharmazeutische zusammensetzungen enthaltend dobutamine |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6017966A (de) |
| EP (1) | EP0859635B1 (de) |
| JP (1) | JPH11504344A (de) |
| AT (1) | ATE179075T1 (de) |
| AU (1) | AU7308296A (de) |
| CA (1) | CA2232419A1 (de) |
| DE (2) | DE69602208T2 (de) |
| ES (1) | ES2132964T3 (de) |
| FR (1) | FR2740337B1 (de) |
| GR (1) | GR3030026T3 (de) |
| WO (1) | WO1997015329A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19756758C1 (de) * | 1997-12-19 | 1999-08-05 | Solvay Pharm Gmbh | Stabilisierte pharmazeutische Zusammensetzung enthaltend Dopamin oder Dobutamin |
| CN112444497A (zh) * | 2020-10-23 | 2021-03-05 | 马鞍山丰原制药有限公司 | 一种盐酸多巴酚丁胺含量的检测方法 |
| CN114617844A (zh) * | 2022-04-20 | 2022-06-14 | 江苏吴中医药集团有限公司 | 一种盐酸多巴酚丁胺水针注射液的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3808317A (en) * | 1969-10-29 | 1974-04-30 | Alcon Labor Inc | Stabilized aqueous borate complexes of biologically active catechol amines |
| FR2231377B1 (de) * | 1973-05-29 | 1977-11-04 | Barnes Hind Pharm Inc | |
| US3966905A (en) * | 1973-05-29 | 1976-06-29 | Barnes-Hind Pharmaceuticals, Inc. | Stabilized catechol amine solutions |
| RO93391B (ro) * | 1984-12-20 | 1988-03-31 | Eli Lilly And Company | Procedeu pentru prepararea unor saruri de dobutamina |
| US4980159A (en) * | 1989-05-23 | 1990-12-25 | Bristol-Myers Squibb Company | Processes and compositions for the topical application of β-adrenergic agonists for pilomotor effects |
| AU5680994A (en) * | 1992-12-10 | 1994-07-04 | Abbott Laboratories | Stabilized catecholamine solutions |
-
1995
- 1995-10-27 FR FR9512688A patent/FR2740337B1/fr not_active Expired - Fee Related
-
1996
- 1996-10-25 DE DE69602208T patent/DE69602208T2/de not_active Revoked
- 1996-10-25 EP EP96934972A patent/EP0859635B1/de not_active Revoked
- 1996-10-25 ES ES96934972T patent/ES2132964T3/es not_active Expired - Lifetime
- 1996-10-25 JP JP9516367A patent/JPH11504344A/ja active Pending
- 1996-10-25 WO PCT/FR1996/001671 patent/WO1997015329A1/fr not_active Application Discontinuation
- 1996-10-25 CA CA002232419A patent/CA2232419A1/fr not_active Abandoned
- 1996-10-25 DE DE0859635T patent/DE859635T1/de active Pending
- 1996-10-25 AU AU73082/96A patent/AU7308296A/en not_active Abandoned
- 1996-10-25 AT AT96934972T patent/ATE179075T1/de active
-
1998
- 1998-04-24 US US09/066,528 patent/US6017966A/en not_active Expired - Fee Related
-
1999
- 1999-04-22 GR GR990400384T patent/GR3030026T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69602208D1 (de) | 1999-05-27 |
| GR3030026T3 (en) | 1999-07-30 |
| US6017966A (en) | 2000-01-25 |
| ES2132964T3 (es) | 1999-08-16 |
| WO1997015329A1 (fr) | 1997-05-01 |
| AU7308296A (en) | 1997-05-15 |
| JPH11504344A (ja) | 1999-04-20 |
| ATE179075T1 (de) | 1999-05-15 |
| FR2740337B1 (fr) | 1997-11-21 |
| CA2232419A1 (fr) | 1997-05-01 |
| EP0859635B1 (de) | 1999-04-21 |
| EP0859635A1 (de) | 1998-08-26 |
| FR2740337A1 (fr) | 1997-04-30 |
| DE859635T1 (de) | 1999-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent | ||
| 8331 | Complete revocation |