DE69534747D1 - Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure - Google Patents
Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäureInfo
- Publication number
- DE69534747D1 DE69534747D1 DE69534747T DE69534747T DE69534747D1 DE 69534747 D1 DE69534747 D1 DE 69534747D1 DE 69534747 T DE69534747 T DE 69534747T DE 69534747 T DE69534747 T DE 69534747T DE 69534747 D1 DE69534747 D1 DE 69534747D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- haemophilus influenzae
- pili
- relates
- adhesine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 241000606768 Haemophilus influenzae Species 0.000 title abstract 4
- 229940047650 haemophilus influenzae Drugs 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 108020004414 DNA Proteins 0.000 abstract 4
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US277231 | 1994-07-19 | ||
| US08/277,231 US5643725A (en) | 1994-07-19 | 1994-07-19 | Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable haemophilus influenzae |
| US08/477,326 US5968769A (en) | 1994-07-19 | 1995-06-07 | Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable Haemophilus influenzae |
| US08/473,750 US5834187A (en) | 1994-07-19 | 1995-06-07 | Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable Haemophilus influenzae |
| US477326 | 1995-06-07 | ||
| PCT/US1995/008789 WO1996002648A1 (en) | 1994-07-19 | 1995-07-13 | Lkp pilin structural genes and operon of nontypable haemophilus influenzae |
| US473750 | 1999-12-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69534747D1 true DE69534747D1 (de) | 2006-04-06 |
| DE69534747T2 DE69534747T2 (de) | 2006-07-06 |
Family
ID=27402882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69534747T Expired - Lifetime DE69534747T2 (de) | 1994-07-19 | 1995-07-13 | Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0771352B1 (de) |
| JP (2) | JP2001521361A (de) |
| KR (1) | KR100391483B1 (de) |
| AT (1) | ATE315648T1 (de) |
| AU (1) | AU706937B2 (de) |
| CA (1) | CA2195090C (de) |
| DE (1) | DE69534747T2 (de) |
| DK (1) | DK0771352T3 (de) |
| ES (1) | ES2257741T3 (de) |
| PT (1) | PT771352E (de) |
| WO (1) | WO1996002648A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0771352T3 (da) * | 1994-07-19 | 2006-03-06 | Wyeth Corp | Ikke-typebestemmelig Haemophilus influenzae-LKP-spids-adhesinprotein og nukleinsyre |
| US6001564A (en) * | 1994-09-12 | 1999-12-14 | Infectio Diagnostic, Inc. | Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories |
| US20020055101A1 (en) | 1995-09-11 | 2002-05-09 | Michel G. Bergeron | Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories |
| US5646259A (en) | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins |
| AU754024B2 (en) * | 1995-03-24 | 2002-10-31 | St. Louis University | Haemophilus adhesion proteins |
| US5750116A (en) * | 1995-06-02 | 1998-05-12 | Bactex, Inc. | Haemophilus influenzae pilus vaccines |
| US5994066A (en) * | 1995-09-11 | 1999-11-30 | Infectio Diagnostic, Inc. | Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories |
| US20030049636A1 (en) | 1999-05-03 | 2003-03-13 | Bergeron Michel G. | Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories |
| US20100267012A1 (en) | 1997-11-04 | 2010-10-21 | Bergeron Michel G | Highly conserved genes and their use to generate probes and primers for detection of microorganisms |
| US6335182B1 (en) * | 1999-03-16 | 2002-01-01 | Aventis Pasteur Limited | Recombinant Haemophilus influenzae adhesin proteins |
| US7785609B1 (en) | 1999-03-16 | 2010-08-31 | Sanofi Pasteur Limited | Recombinant Haemophilus influenzae adhesin proteins |
| CA2906516C (en) | 1999-09-28 | 2017-03-07 | Geneohm Sciences Canada Inc. | Nucleic acids and methods for the detection of streptococcus |
| DE602004026218D1 (de) * | 2003-12-23 | 2010-05-06 | Nationwide Childrens Hospital | Pili von haemophilus influenzae typ iv |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989012460A1 (en) * | 1988-06-16 | 1989-12-28 | Bactex, Inc. | Haemophilus influenzae pilus vaccines |
| GB9205704D0 (en) * | 1992-03-16 | 1992-04-29 | Connaught Lab | High molecular weight membrane proteins of non-typeable haemophilus |
| DK0771352T3 (da) * | 1994-07-19 | 2006-03-06 | Wyeth Corp | Ikke-typebestemmelig Haemophilus influenzae-LKP-spids-adhesinprotein og nukleinsyre |
-
1995
- 1995-07-13 DK DK95926676T patent/DK0771352T3/da active
- 1995-07-13 ES ES95926676T patent/ES2257741T3/es not_active Expired - Lifetime
- 1995-07-13 AU AU30972/95A patent/AU706937B2/en not_active Ceased
- 1995-07-13 JP JP50514296A patent/JP2001521361A/ja active Pending
- 1995-07-13 CA CA2195090A patent/CA2195090C/en not_active Expired - Fee Related
- 1995-07-13 AT AT95926676T patent/ATE315648T1/de not_active IP Right Cessation
- 1995-07-13 DE DE69534747T patent/DE69534747T2/de not_active Expired - Lifetime
- 1995-07-13 EP EP95926676A patent/EP0771352B1/de not_active Expired - Lifetime
- 1995-07-13 PT PT95926676T patent/PT771352E/pt unknown
- 1995-07-13 KR KR1019970700328A patent/KR100391483B1/ko not_active IP Right Cessation
- 1995-07-13 WO PCT/US1995/008789 patent/WO1996002648A1/en active IP Right Grant
-
2007
- 2007-09-26 JP JP2007249223A patent/JP2008067707A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK0771352T3 (da) | 2006-03-06 |
| DE69534747T2 (de) | 2006-07-06 |
| EP0771352A1 (de) | 1997-05-07 |
| JP2008067707A (ja) | 2008-03-27 |
| PT771352E (pt) | 2006-05-31 |
| ES2257741T3 (es) | 2006-08-01 |
| EP0771352B1 (de) | 2006-01-11 |
| CA2195090C (en) | 2011-04-19 |
| ATE315648T1 (de) | 2006-02-15 |
| AU3097295A (en) | 1996-02-16 |
| CA2195090A1 (en) | 1996-02-01 |
| KR100391483B1 (ko) | 2003-10-30 |
| JP2001521361A (ja) | 2001-11-06 |
| WO1996002648A1 (en) | 1996-02-01 |
| AU706937B2 (en) | 1999-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1340373C (en) | Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin | |
| KR860001515B1 (ko) | 사람의 전(前) 성장(pre-growth)호르몬의 아미노산 배열을 함유하는 단백질의 제조방법 | |
| Brusilow et al. | Organization and sequence of the genes coding for the proton-translocating ATPase of Bacillus megaterium | |
| ATE315648T1 (de) | Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure | |
| BRPI0511118A (pt) | polipeptìdeos de haemophilus influenzae não transcritos | |
| DK1005540T3 (da) | IKK-beta-proteiner, nukleinsyrer og fremgangsmåder | |
| DE69840387D1 (de) | Nik proteine, nukleinsäure sowie verfahren | |
| DE69841894D1 (de) | Äusseres Membranpolypeptid von Chlamydia pneumoniae sowie Fragmente davon und deren Verwendung, insbesondere zur Diagnose, Prävention und Behandlung einer Infektion | |
| HK1032981A1 (en) | Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection | |
| ATE327326T1 (de) | Fhit proteine und nukleinsäuren sowie darauf basierende verfahren | |
| HUP0004611A2 (hu) | APRIL, egy új növekedési hatású fehérje | |
| WO1998055606A3 (en) | Lactoferrin receptor genes of moraxella | |
| ATE338113T1 (de) | Transferrin-rezeptor gene von haemophilus | |
| EP0837130A3 (de) | M Protein-Analog von Streptococcus pneumoniae | |
| FI64187C (fi) | Foerfarande foer rening av en produkt bestaoende huvudsakligenav cdna-fragment med samma laengd vilka har en specifik n ukeotidsekvens och minst ett restriktionsstaelle och foer a nays av produktens renhet | |
| Kusumoto et al. | Identification of an insertion sequence, IS1203 variant, in a Shiga toxin 2 gene of Escherichia coli 0157: H7 | |
| EP0834568A3 (de) | Speichel-bindendes Protein von Streptococcus pneumoniae | |
| Bahrami et al. | Iron acquisition by Actinobacillus suis: identification and characterization of a single-component haemoglobin receptor and encoding gene | |
| EP0845535A3 (de) | Leader peptidase (lep) aus Streptococcus | |
| ATE278011T1 (de) | Human dnase ii | |
| US7015033B1 (en) | Co-expression of recombination proteins | |
| EP0816502A3 (de) | Mur A-1, ein UDP-N-Acetylglucosamine-Enolpyruvyltransferase, aus Streptococcus pneumoniae | |
| EP0846766A3 (de) | IgA Fc-bindendes Protein von Streptococcus pneumoniae | |
| AU2001256032A1 (en) | Co-expression of recombinant proteins | |
| AU2009230776B2 (en) | Neisseria meningitidis antigens and compositions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |