DE69530072D1 - System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung - Google Patents

System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung

Info

Publication number
DE69530072D1
DE69530072D1 DE69530072T DE69530072T DE69530072D1 DE 69530072 D1 DE69530072 D1 DE 69530072D1 DE 69530072 T DE69530072 T DE 69530072T DE 69530072 T DE69530072 T DE 69530072T DE 69530072 D1 DE69530072 D1 DE 69530072D1
Authority
DE
Germany
Prior art keywords
lens
imaging system
fluorescent imaging
macro scanning
macro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69530072T
Other languages
English (en)
Other versions
DE69530072T2 (de
Inventor
C Kain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Integenx Acquisition Corp
Original Assignee
Molecular Dynamics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Dynamics Inc filed Critical Molecular Dynamics Inc
Publication of DE69530072D1 publication Critical patent/DE69530072D1/de
Application granted granted Critical
Publication of DE69530072T2 publication Critical patent/DE69530072T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE69530072T 1994-12-08 1995-10-20 System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung Expired - Lifetime DE69530072T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35160394A 1994-12-08 1994-12-08
US351603 1994-12-08
PCT/US1995/013531 WO1996018205A1 (en) 1994-12-08 1995-10-20 Fluorescence imaging system employing a macro scanning objective

Publications (2)

Publication Number Publication Date
DE69530072D1 true DE69530072D1 (de) 2003-04-30
DE69530072T2 DE69530072T2 (de) 2004-03-04

Family

ID=23381580

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69530072T Expired - Lifetime DE69530072T2 (de) 1994-12-08 1995-10-20 System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung

Country Status (6)

Country Link
US (2) US5719391A (de)
EP (1) EP0746865B1 (de)
JP (1) JP3794703B2 (de)
AU (1) AU3963595A (de)
DE (1) DE69530072T2 (de)
WO (1) WO1996018205A1 (de)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6411377B1 (en) * 1991-04-02 2002-06-25 Hitachi, Ltd. Optical apparatus for defect and particle size inspection
US6741344B1 (en) * 1994-02-10 2004-05-25 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US6090555A (en) * 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US20030017081A1 (en) * 1994-02-10 2003-01-23 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US7215424B1 (en) 1998-03-03 2007-05-08 J.A. Woollam Co., Inc. Broadband ellipsometer or polarimeter system including at least one multiple element lens
US7518725B1 (en) 1995-09-20 2009-04-14 J.A. Woollam Co., Inc. Temperature controlled lens
WO1997038353A1 (en) * 1996-04-08 1997-10-16 Liberty Technologies, Inc. Storage phosphor erasure using yellow and/or infrared
WO1997043611A1 (en) * 1996-05-16 1997-11-20 Affymetrix, Inc. Systems and methods for detection of labeled materials
CN1609593B (zh) * 1996-08-16 2012-04-25 Ge保健尼亚加拉公司 用于分析井板、凝胶和斑点的数字成像系统
JP4323571B2 (ja) 1997-01-31 2009-09-02 エックスワイ， インコーポレイテッド 光学装置
US6124928A (en) * 1997-03-07 2000-09-26 Kaiser Optical Systems, Inc. Methods and apparatus for obtaining a selectively polarized induced emission
US6534308B1 (en) * 1997-03-27 2003-03-18 Oncosis, Llc Method and apparatus for selectively targeting specific cells within a mixed cell population
US5874266A (en) * 1997-03-27 1999-02-23 Palsson; Bernhard O. Targeted system for removing tumor cells from cell populations
US6753161B2 (en) * 1997-03-27 2004-06-22 Oncosis Llc Optoinjection methods
US6469311B1 (en) 1997-07-16 2002-10-22 Molecular Devices Corporation Detection device for light transmitted from a sensed volume
US6071748A (en) 1997-07-16 2000-06-06 Ljl Biosystems, Inc. Light detection device
US5943129A (en) * 1997-08-07 1999-08-24 Cambridge Research & Instrumentation Inc. Fluorescence imaging system
US6043506A (en) * 1997-08-13 2000-03-28 Bio-Rad Laboratories, Inc. Multi parameter scanner
US6326605B1 (en) 1998-02-20 2001-12-04 Ljl Biosystems, Inc. Broad range light detection system
US6576476B1 (en) 1998-09-02 2003-06-10 Ljl Biosystems, Inc. Chemiluminescence detection method and device
US6825921B1 (en) 1999-11-10 2004-11-30 Molecular Devices Corporation Multi-mode light detection system
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6051835A (en) * 1998-01-07 2000-04-18 Bio-Rad Laboratories, Inc. Spectral imaging apparatus and methodology
US6201639B1 (en) 1998-03-20 2001-03-13 James W. Overbeck Wide field of view and high speed scanning microscopy
US6510001B1 (en) 1998-02-19 2003-01-21 Leica Microsystems Heidelberg Gmbh Optical arrangement with a spectrally selective element
US6185030B1 (en) 1998-03-20 2001-02-06 James W. Overbeck Wide field of view and high speed scanning microscopy
US6642018B1 (en) 1998-03-27 2003-11-04 Oncosis Llc Method for inducing a response in one or more targeted cells
US6140653A (en) * 1998-03-27 2000-10-31 Vysis, Inc. Large-field fluorescence imaging apparatus
US6078390A (en) * 1998-05-04 2000-06-20 General Scanning, Inc. Scanning system and method of operation for automatically setting detection sensitivity
US6472671B1 (en) 2000-02-09 2002-10-29 Jean I. Montagu Quantified fluorescence microscopy
CA2328609A1 (en) * 1998-05-16 1999-11-25 Pe Corporation (Ny) Instrument for monitoring polymerase chain reaction of dna
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
US6818437B1 (en) 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
US6627446B1 (en) 1998-07-02 2003-09-30 Amersham Biosciences (Sv) Corp Robotic microchannel bioanalytical instrument
AU5667599A (en) 1998-07-27 2000-02-21 Ljl Biosystems, Inc. Apparatus and methods for time-resolved spectroscopic measurements
AU5223899A (en) 1998-07-27 2000-02-21 Ljl Biosystems, Inc. Apparatus and methods for spectroscopic measurements
EP1100534B1 (de) 1998-07-30 2008-01-16 XY, Inc. System zur künstlichen nicht-chirurgischen besamung von pferden
US6455861B1 (en) 1998-11-24 2002-09-24 Cambridge Research & Instrumentation, Inc. Fluorescence polarization assay system and method
AU3104500A (en) 1998-11-25 2000-06-13 Phormax Corporation Single-head phosphor screen scanning systems
AU3005400A (en) 1999-02-23 2000-09-14 Ljl Biosystems, Inc. Frequency-domain light detection device
US6355934B1 (en) 1999-02-26 2002-03-12 Packard Biochip Technologies Imaging system for an optical scanner
US6075613A (en) * 1999-02-26 2000-06-13 General Scanning, Inc. Optical scanner calibration device
US7423750B2 (en) * 2001-11-29 2008-09-09 Applera Corporation Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
US7387891B2 (en) * 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
US20050279949A1 (en) * 1999-05-17 2005-12-22 Applera Corporation Temperature control for light-emitting diode stabilization
US7410793B2 (en) * 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
DE19923822A1 (de) 1999-05-19 2000-11-23 Zeiss Carl Jena Gmbh Scannende Anordnung, vorzugsweise zur Erfassung von Fluoreszenzlicht
WO2001009592A1 (en) * 1999-07-30 2001-02-08 California Institute Of Technology System and method for monitoring cellular activity
DE19936999C2 (de) * 1999-08-02 2002-03-14 Jena Optronik Gmbh Anordnung zum Erfassen der Fluoreszenzstrahlung von matrixförmigen Probenträgern
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
AU785290B2 (en) 1999-11-30 2006-12-21 Intrexon Corporation Method and apparatus for selectively targeting specific cells within a cell population
NZ545311A (en) 2000-05-09 2008-03-28 Xy Inc Flow cytometer for high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa
US20040224421A1 (en) * 2000-06-15 2004-11-11 Deweerd Herman Bi-directional scanning method
DE10029680B4 (de) * 2000-06-23 2016-06-16 Leica Microsystems Cms Gmbh Mikroskop-Aufbau
US7158224B2 (en) 2000-06-25 2007-01-02 Affymetrix, Inc. Optically active substrates
AU2002232892B2 (en) 2000-10-24 2008-06-26 Intrexon Corporation Method and device for selectively targeting cells within a three -dimensional specimen
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
CA2822983C (en) 2000-11-29 2017-05-09 Xy, Llc System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
DE10127611C2 (de) * 2001-06-07 2003-08-07 Jena Optronik Gmbh Anordnung zum Anregen und Auslesen der Fluoreszenzstrahlung eines Probenträgers mit einer Vielzahl von Einzelproben
EP1428018B1 (de) 2001-09-06 2010-06-09 Straus Holdings Inc. Schneller und empfindlicher nachweis von molekülen
US7635588B2 (en) * 2001-11-29 2009-12-22 Applied Biosystems, Llc Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
CA2422224A1 (en) 2002-03-15 2003-09-15 Affymetrix, Inc. System, method, and product for scanning of biological materials
US20040002154A1 (en) * 2002-04-19 2004-01-01 Palsson Bernhard O. Methods for preparing libraries of unique tags and related screening methods
EP3312594B1 (de) 2002-05-17 2019-07-24 Life Technologies Corporation Vorrichtung zur differenzierung mehrerer fluoreszenzsignale nach anregungswellenlänge
FR2842407B1 (fr) * 2002-07-18 2005-05-06 Mauna Kea Technologies "procede et appareillage d'imagerie de fluorescence confocale fibree"
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
BRPI0313163B1 (pt) 2002-08-01 2015-11-17 Univ Colorado State sistema de separação de células espermáticas a baixa pressão
AU2003265471B2 (en) 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
WO2004025331A2 (en) * 2002-09-16 2004-03-25 Rensselaer Polytechnic Institute Microscope with extended field of vision
DK2305173T3 (en) 2003-03-28 2016-08-22 Inguran Llc Apparatus and method for providing sorted particles
WO2004102627A2 (en) * 2003-05-08 2004-11-25 Alara, Inc. Method and apparatus for radiation image erasure
US20060263829A1 (en) 2003-05-15 2006-11-23 Evans Kenneth M Efficient haploid cell sorting flow cytometer systems
TWI329208B (en) * 2003-06-03 2010-08-21 Oerlikon Trading Ag Optical substrate for enhanced detectability of fluorescence
US7285789B2 (en) * 2003-06-06 2007-10-23 Oc Oerlikon Balzers Ag Optical device for surface-generated fluorescence
DE10344060A1 (de) * 2003-09-23 2005-05-04 Zeiss Carl Jena Gmbh Konfokales Laser-Scanning-Mikroskop
US20050095578A1 (en) * 2003-10-31 2005-05-05 Koller Manfred R. Method and apparatus for cell permeabilization
US6940641B2 (en) * 2003-11-18 2005-09-06 Olympus Corporation Fluorescence observation apparatus
DE102004008762B4 (de) * 2004-02-23 2006-10-12 Erwin Kayser-Threde Gmbh Verfahren und Vorrichtung zur Detektion und zum Identifizieren von Biopartikeln
US7425426B2 (en) * 2004-03-15 2008-09-16 Cyntellect, Inc. Methods for purification of cells based on product secretion
AU2005229073B2 (en) 2004-03-29 2010-08-19 Inguran, Llc Sperm suspensions for use in insemination
US7833147B2 (en) 2004-07-22 2010-11-16 Inguran, LLC. Process for enriching a population of sperm cells
PL2884258T3 (pl) 2004-07-27 2017-04-28 Beckman Coulter, Inc. Poprawa zdolności dyskryminacji w cytometrii przepływowej przy użyciu transformacji geometrycznej realizowanej za pomocą komputera
US7682782B2 (en) * 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
ES2285578T3 (es) * 2005-01-18 2007-11-16 F. Hoffmann-La Roche Ag Visualizacion de señales de fluorescencia utilizando telecentricidad.
US7768638B2 (en) * 2005-03-18 2010-08-03 Illumina, Inc. Systems for and methods of facilitating focusing an optical scanner
US8351026B2 (en) 2005-04-22 2013-01-08 Affymetrix, Inc. Methods and devices for reading microarrays
US7397042B2 (en) * 2005-08-24 2008-07-08 Dr. Chip Biotechnology Incorporation Optical detection apparatus and method thereof
EP1937829A4 (de) * 2005-09-26 2011-08-03 Rapid Micro Biosystems Inc Kassette mit wachstumsmedium
US7329860B2 (en) 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
US8055098B2 (en) 2006-01-27 2011-11-08 Affymetrix, Inc. System, method, and product for imaging probe arrays with small feature sizes
US9445025B2 (en) 2006-01-27 2016-09-13 Affymetrix, Inc. System, method, and product for imaging probe arrays with small feature sizes
US7846391B2 (en) 2006-05-22 2010-12-07 Lumencor, Inc. Bioanalytical instrumentation using a light source subsystem
US9255348B2 (en) 2006-08-25 2016-02-09 The Trustees Of Columbia University In The City Of New York Systems and methods for biodosimetry with biochip using gene expression signatures
WO2008073168A2 (en) * 2006-08-25 2008-06-19 The Trustees Of Columbia University In The City Of New York Systems and methods for high-throughput radiation biodosimetry
US7791013B2 (en) * 2006-11-21 2010-09-07 Illumina, Inc. Biological microarray line scanning method and system
US7813013B2 (en) * 2006-11-21 2010-10-12 Illumina, Inc. Hexagonal site line scanning method and system
US8098375B2 (en) 2007-08-06 2012-01-17 Lumencor, Inc. Light emitting diode illumination system
US7988918B2 (en) 2007-11-01 2011-08-02 Complete Genomics, Inc. Structures for enhanced detection of fluorescence
US9551026B2 (en) 2007-12-03 2017-01-24 Complete Genomincs, Inc. Method for nucleic acid detection using voltage enhancement
CA2738317C (en) 2008-09-24 2020-01-14 Straus Holdings Inc. Imaging analyzer for testing analytes
US8374818B2 (en) * 2008-12-19 2013-02-12 Affymetrix, Inc. System, method and apparatus for calibrating inspection tools
WO2010081052A1 (en) * 2009-01-09 2010-07-15 Cyntellect, Inc. Genetic analysis of cells
JP2012514981A (ja) 2009-01-12 2012-07-05 イントレクソン コーポレイション 細胞コロニーのレーザーを介在したセクション化及び移行
US8242462B2 (en) 2009-01-23 2012-08-14 Lumencor, Inc. Lighting design of high quality biomedical devices
US9767342B2 (en) 2009-05-22 2017-09-19 Affymetrix, Inc. Methods and devices for reading microarrays
US9791313B2 (en) 2010-12-01 2017-10-17 MKS Technology Spectrometer
US8466436B2 (en) 2011-01-14 2013-06-18 Lumencor, Inc. System and method for metered dosage illumination in a bioanalysis or other system
US8389957B2 (en) 2011-01-14 2013-03-05 Lumencor, Inc. System and method for metered dosage illumination in a bioanalysis or other system
US10837879B2 (en) 2011-11-02 2020-11-17 Complete Genomics, Inc. Treatment for stabilizing nucleic acid arrays
MX368123B (es) 2011-11-07 2019-09-19 Rapid Micro Biosystems Inc Cassette para pruebas de esterilidad.
US8967846B2 (en) 2012-01-20 2015-03-03 Lumencor, Inc. Solid state continuous white light source
CN104364388B (zh) 2012-04-16 2017-12-19 快速微型生物系统公司 细胞培养装置
US9217561B2 (en) 2012-06-15 2015-12-22 Lumencor, Inc. Solid state light source for photocuring
DE102012111601A1 (de) * 2012-11-29 2014-03-13 Limo Patentverwaltung Gmbh & Co. Kg Scanvorrichtung zum Scannen eines Laserstrahls in einer Arbeitsebene
KR102044864B1 (ko) * 2012-12-13 2019-12-06 삼성디스플레이 주식회사 레이저 패터닝 검사장치
JP6590793B2 (ja) * 2013-05-31 2019-10-16 エムケイエス・テクノロジー，インコーポレーテッド 分光器、及び分光サンプルの表面全体に分光器の集束入射ビームを移動させる方法
CN206281782U (zh) 2013-08-28 2017-06-27 伊鲁米那股份有限公司 检查设备及光学检测装置
US10540783B2 (en) * 2013-11-01 2020-01-21 Illumina, Inc. Image analysis useful for patterned objects
CA2951118C (en) 2014-05-16 2024-01-09 Illumina, Inc. Nucleic acid synthesis techniques
WO2016057950A1 (en) 2014-10-09 2016-04-14 Illumina, Inc. Method and device for separating immiscible liquids to effectively isolate at least one of the liquids
TWI772752B (zh) * 2017-01-07 2022-08-01 美商伊路米納有限公司 光學偵測裝置以及方法
GB201701688D0 (en) 2017-02-01 2017-03-15 Illumia Inc System and method with fiducials in non-recliner layouts
GB201701691D0 (en) 2017-02-01 2017-03-15 Illumina Inc System and method with reflective fiducials
GB201701686D0 (en) 2017-02-01 2017-03-15 Illunina Inc System & method with fiducials having offset layouts
GB201701689D0 (en) 2017-02-01 2017-03-15 Illumia Inc System and method with fiducials of non-closed shapes
CN109414673B (zh) 2017-02-01 2021-09-07 伊鲁米那股份有限公司 具有响应于多个激发频率的基准的系统和方法
WO2018183745A1 (en) 2017-03-30 2018-10-04 Illumina, Inc. Genomic data analysis system and method
CN109444192B (zh) * 2018-11-27 2024-05-28 金华职业技术学院 一种脉冲激光加热的高压样品测试装置
NL2023310B1 (en) 2019-03-21 2020-09-28 Illumina Inc Training data generation for artificial intelligence-based sequencing
NL2023311B9 (en) 2019-03-21 2021-03-12 Illumina Inc Artificial intelligence-based generation of sequencing metadata
US11210554B2 (en) 2019-03-21 2021-12-28 Illumina, Inc. Artificial intelligence-based generation of sequencing metadata
NL2023314B1 (en) 2019-03-21 2020-09-28 Illumina Inc Artificial intelligence-based quality scoring
NL2023316B1 (en) 2019-03-21 2020-09-28 Illumina Inc Artificial intelligence-based sequencing
WO2020191390A2 (en) 2019-03-21 2020-09-24 Illumina, Inc. Artificial intelligence-based quality scoring
NL2023312B1 (en) 2019-03-21 2020-09-28 Illumina Inc Artificial intelligence-based base calling
US20210265018A1 (en) 2020-02-20 2021-08-26 Illumina, Inc. Knowledge Distillation and Gradient Pruning-Based Compression of Artificial Intelligence-Based Base Caller
US11188778B1 (en) 2020-05-05 2021-11-30 Illumina, Inc. Equalization-based image processing and spatial crosstalk attenuator
US20220414853A1 (en) 2021-06-25 2022-12-29 Illumina, Inc. Fiducials for use in registration of a patterned surface
WO2022269033A1 (en) 2021-06-25 2022-12-29 Illumina Cambridge Limited Linear fourier fiducial
US11455487B1 (en) 2021-10-26 2022-09-27 Illumina Software, Inc. Intensity extraction and crosstalk attenuation using interpolation and adaptation for base calling
WO2023003757A1 (en) 2021-07-19 2023-01-26 Illumina Software, Inc. Intensity extraction with interpolation and adaptation for base calling
US20230088338A1 (en) 2021-09-10 2023-03-23 Illumina, Inc. Sequencer focus quality metrics and focus tracking for periodically patterned surfaces
WO2023049212A2 (en) 2021-09-22 2023-03-30 Illumina, Inc. State-based base calling
WO2023183937A1 (en) 2022-03-25 2023-09-28 Illumina, Inc. Sequence-to-sequence base calling
US20230407386A1 (en) 2022-06-09 2023-12-21 Illumina, Inc. Dependence of base calling on flow cell tilt
WO2024025806A1 (en) 2022-07-27 2024-02-01 Illumina, Inc. Motion feedback using patterned flowcells
WO2024072799A1 (en) 2022-09-26 2024-04-04 Illumina, Inc. Flow cell based motion system calibration and control methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657537A (en) * 1970-04-03 1972-04-18 Bausch & Lomb Computerized slit-scan cyto-fluorometer for automated cell recognition
US4058732A (en) * 1975-06-30 1977-11-15 Analytical Radiation Corporation Method and apparatus for improved analytical fluorescent spectroscopy
JPS53135660A (en) * 1977-04-30 1978-11-27 Olympus Optical Co Ltd Fluorescent photometric microscope using laser light
DE3422143A1 (de) * 1984-06-14 1985-12-19 Josef Prof. Dr. Bille Geraet zur wafer-inspektion
US4877965A (en) * 1985-07-01 1989-10-31 Diatron Corporation Fluorometer
US5144477A (en) * 1988-04-11 1992-09-01 Medical Research Council Method of operating a scanning confocal imaging system
US4945287A (en) * 1988-06-13 1990-07-31 Eotron Corporation Multiple pentaprism scanning device and method
US5022757A (en) * 1989-01-23 1991-06-11 Modell Mark D Heterodyne system and method for sensing a target substance
GB9014263D0 (en) * 1990-06-27 1990-08-15 Dixon Arthur E Apparatus and method for spatially- and spectrally- resolvedmeasurements
US5260578A (en) * 1991-04-10 1993-11-09 Mayo Foundation For Medical Education And Research Confocal imaging system for visible and ultraviolet light
US5184012A (en) * 1991-12-26 1993-02-02 Olympus Optical Co., Ltd. Optical scanning apparatus with axis deviation correction
JPH05203878A (ja) * 1992-01-27 1993-08-13 Jeol Ltd 走査型レーザー顕微鏡
JP3292935B2 (ja) * 1993-05-18 2002-06-17 富士写真フイルム株式会社 蛍光分光画像計測装置
US5381224A (en) * 1993-08-30 1995-01-10 A. E. Dixon Scanning laser imaging system

Also Published As

Publication number Publication date
JP3794703B2 (ja) 2006-07-12
US5719391A (en) 1998-02-17
EP0746865A4 (de) 1999-09-01
DE69530072T2 (de) 2004-03-04
EP0746865A1 (de) 1996-12-11
WO1996018205A1 (en) 1996-06-13
US5672880A (en) 1997-09-30
EP0746865B1 (de) 2003-03-26
AU3963595A (en) 1996-06-26
JPH09509506A (ja) 1997-09-22

Similar Documents

Publication Publication Date Title
DE69530072D1 (de) System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung
DE69609096T2 (de) Bildabtastungssystem
DE69519220T2 (de) Einzeltafel-farbbildprojektionssystem mit verbesserter abtastung
DE69619320D1 (de) Bildverschiebung unter Verwendung einer Referenzstelle
DE69608069D1 (de) Optischer Abtaster mit verbesserter Seitendeckung eines Gegenstandes
DE69531483D1 (de) Optisches Abtastgerät
GB2300727B (en) Imaging lens for optical scanner
DE69527767D1 (de) Neuronales Netzwerk mit einbegriffenen direkten optischen Bildern
DE69933905D1 (de) Optischer Abtaster mit Belichtungssteuerung
DE69527386T2 (de) Mit Linse versehener Niveaufühler unter Verwendung eines optischen Punkts
DE69932793T8 (de) Optisches System zum Lichtabtasten und dessen Verwendung in einer Bilderzeugungsvorrichtung
DE69732865D1 (de) Kodierer mit Mitteln zur Ergänzung eines digitalen Bildes mit Bildelementen
DE69728483D1 (de) Lichtstrahlabtastgerät zur Verwendung mit Bilderzeugungsgerät
DE69533812D1 (de) Bildabtaster mit Bildkorrekturfunktion
DE69625867D1 (de) Optisches Abtastgerät
DE69600298D1 (de) Optisches Abtastgerät
DE69733682D1 (de) Mehrstrahllichtquelle und optisches Mehrstrahlabtastsystem unter Verwendung dieser Quelle
DE60022704D1 (de) Optisches Mehrstrahlabtastsystem und Bilderzeugungsgerät unter Verwendung desselben
DE69127963D1 (de) Optisches Abtastsystem
DE60120538D1 (de) Optisches System zum Lichtabtasten und Bilderzeugungsvorrichtung unter Verwendung desselben
DE60045655D1 (de) Optisches Mehrstrahlabtastsystem und Bilderzeugungsvorrichtung unter Verwendung desselben
DE69708208D1 (de) Abtastbelichtungsapparat mit System zur Detektion einer Oberflächenlage
DE69117552D1 (de) Optisches Dokumentabtastsystem
DE69604917T2 (de) Lichtsammelndes system zur digitalisierung von filmbildern
DE69735690D1 (de) Gerät zur Bilderzeugung unter Verwendung eines Zwischenübertragungselementes

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AMERSHAM BIOSCIENCES (SV) CORP. (N.D.GES.D. STAATE

8327 Change in the person/name/address of the patent owner

Owner name: GE HEALTHCARE )SV) CORP.(N.D.GES.D.STAATES DELAWAR